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Henrik Hammarén
Henrik Hammarén
Postdoc, EMBL Heidelberg
E-mail confirmado em embl.de
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A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties
JM Murphy, Q Zhang, SN Young, ML Reese, FP Bailey, PA Eyers, ...
Biochemical Journal 457 (2), 323-334, 2014
2712014
Anomalous and normal diffusion of proteins and lipids in crowded lipid membranes
M Javanainen, H Hammaren, L Monticelli, JH Jeon, MS Miettinen, ...
Faraday discussions 161, 397-417, 2013
2142013
Membrane proteins diffuse as dynamic complexes with lipids
PS Niemela, MS Miettinen, L Monticelli, H Hammaren, P Bjelkmar, ...
Journal of the American Chemical Society 132 (22), 7574-7575, 2010
1942010
The regulation of JAKs in cytokine signaling and its breakdown in disease
HM Hammarén, AT Virtanen, J Raivola, O Silvennoinen
Cytokine 118, 48-63, 2019
1932019
Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase
Y Shan, K Gnanasambandan, D Ungureanu, ET Kim, H Hammarén, ...
Nature structural & molecular biology 21 (7), 579-584, 2014
1542014
ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation
HM Hammarén, D Ungureanu, J Grisouard, RC Skoda, SR Hubbard, ...
Proceedings of the National Academy of Sciences 112 (15), 4642-4647, 2015
1062015
Enhancement of adhesion and promotion of osteogenic differentiation of human adipose stem cells by poled electroactive poly (vinylidene fluoride)
J Pärssinen, H Hammarén, R Rahikainen, V Sencadas, C Ribeiro, ...
Journal of Biomedical Materials Research Part A 103 (3), 919-928, 2015
952015
Structural and functional characterization of the JH2 pseudokinase domain of JAK family tyrosine kinase 2 (TYK2)
X Min, D Ungureanu, S Maxwell, H Hammarén, S Thibault, EK Hillert, ...
Journal of Biological Chemistry 290 (45), 27261-27270, 2015
882015
Control of protein stability by post-translational modifications
JM Lee, HM Hammarén, MM Savitski, SH Baek
Nature Communications 14 (1), 201, 2023
802023
New insights into the structure and function of the pseudokinase domain in JAK2
O Silvennoinen, D Ungureanu, Y Niranjan, H Hammaren, ...
Biochemical Society Transactions 41 (4), 1002-1007, 2013
532013
Nucleotide-binding mechanisms in pseudokinases
HM Hammarén, AT Virtanen, O Silvennoinen
Bioscience reports 36 (1), e00282, 2016
472016
Identification and characterization of JAK2 pseudokinase domain small molecule binders
DE Puleo, K Kucera, HM Hammarén, D Ungureanu, AS Newton, ...
ACS medicinal chemistry letters 8 (6), 618-621, 2017
442017
Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses
LN Varghese, D Ungureanu, NPD Liau, SN Young, A Laktyushin, ...
Biochemical Journal 458 (2), 395-405, 2014
392014
Connection between Absorption Properties and Conformational Changes in Deinococcus radiodurans Phytochrome
H Takala, H Lehtivuori, H Hammarén, VP Hytonen, JA Ihalainen
Biochemistry 53 (45), 7076-7085, 2014
352014
Janus kinase 2 activation mechanisms revealed by analysis of suppressing mutations
HM Hammarén, AT Virtanen, BG Abraham, H Peussa, SR Hubbard, ...
Journal of Allergy and Clinical Immunology 143 (4), 1549-1559. e6, 2019
282019
The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains
AS Sanz, Y Niranjan, H Hammarén, D Ungureanu, R Ruijtenbeek, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (10), 1835-1841, 2014
242014
Bifunctional avidin with covalently modifiable ligand binding site
J Leppiniemi, JAE Määttä, H Hammaren, M Soikkeli, M Laitaoja, J Jänis, ...
PLoS One 6 (1), e16576, 2011
242011
Glycolytic flux-signaling controls mouse embryo mesoderm development
H Miyazawa, MT Snaebjornsson, N Prior, E Kafkia, HM Hammarén, ...
Elife 11, e83299, 2022
182022
Hyperactivation of oncogenic JAK3 mutants depend on ATP binding to the pseudokinase domain
J Raivola, HM Hammarén, AT Virtanen, V Bulleeraz, AC Ward, ...
Frontiers in oncology 8, 560, 2018
152018
Thermal proteome profiling: Insights into protein modifications, associations, and functions
C Le Sueur, HM Hammarén, S Sridharan, MM Savitski
Current opinion in chemical biology 71, 102225, 2022
132022
O sistema não pode executar a operação agora. Tente novamente mais tarde.
Artigos 1–20