James Ellis
James Ellis
The Hospital for Sick Children
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Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines
SJ Kattman, AD Witty, M Gagliardi, NC Dubois, M Niapour, A Hotta, J Ellis, ...
Cell stem cell 8 (2), 228-240, 2011
Correction of sickle cell disease in transgenic mouse models by gene therapy
R Pawliuk, KA Westerman, ME Fabry, E Payen, R Tighe, EE Bouhassira, ...
Science 294 (5550), 2368-2371, 2001
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
M Vedadi, D Barsyte-Lovejoy, F Liu, S Rival-Gervier, A Allali-Hassani, ...
Nature chemical biology 7 (8), 566-74, 2011
Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein
AP Wong, CE Bear, S Chin, P Pasceri, TO Thompson, LJ Huan, F Ratjen, ...
Nature biotechnology 30 (9), 876-82, 2012
Silencing and variegation of gammaretrovirus and lentivirus vectors
J Ellis
Human gene therapy 16 (11), 1241-1246, 2005
Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency
A Hotta, AYL Cheung, N Farra, K Vijayaragavan, CA Séguin, JS Draper, ...
Nature methods 6 (5), 370-376, 2009
MBNL proteins repress ES-cell-specific alternative splicing and reprogramming
H Han, M Irimia, PJ Ross, HK Sung, B Alipanahi, L David, A Golipour, ...
Nature 498 (7453), 241-5, 2013
Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation
AYL Cheung, LM Horvath, D Grafodatskaya, P Pasceri, R Weksberg, ...
Human molecular genetics 20 (11), 2103-2115, 2011
A dominant chromatin‐opening activity in 5′ hypersensitive site 3 of the human beta‐globin locus control region.
J Ellis, KC Tan‐Un, A Harper, D Michalovich, N Yannoutsos, S Philipsen, ...
The EMBO journal 15 (3), 562-568, 1996
A vertebrate Polycomb response element governs segmentation of the posterior hindbrain
A Sing, D Pannell, A Karaiskakis, K Sturgeon, M Djabali, J Ellis, ...
Cell 138 (5), 885-897, 2009
Silencing of gene expression: implications for design of retrovirus vectors
D Pannell, J Ellis
Reviews in medical virology 11 (4), 205-217, 2001
Retroviral vector silencing during iPS cell induction: an epigenetic beacon that signals distinct pluripotent states
A Hotta, J Ellis
Journal of cellular biochemistry 105 (4), 940-948, 2008
Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres
E Fussner, M Strauss, U Djuric, R Li, K Ahmed, M Hart, J Ellis, ...
European Molecular Biology Organization reports 13 (11), 92-6, 2012
Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code
D Pannell, CS Osborne, S Yao, T Sukonnik, P Pasceri, A Karaiskakis, ...
The EMBO journal, 2000
Constitutive heterochromatin reorganization during somatic cell reprogramming
E Fussner, U Djuric, M Strauss, A Hotta, C Perez‐Iratxeta, F Lanner, ...
The EMBO journal 30 (9), 1778-1789, 2011
Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications
S Yao, T Sukonnik, T Kean, RR Bharadwaj, P Pasceri, J Ellis
Molecular Therapy 10 (1), 27-36, 2004
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons
K Zaslavsky, WB Zhang, FP McCready, DC Rodrigues, E Deneault, C Loo, ...
Nature neuroscience 22 (4), 556-564, 2019
Synthetic human beta‐globin 5′ HS2 constructs function as locus control regions only in multicopy transgene concatamers.
J Ellis, D Talbot, N Dillon, F Grosveld
The EMBO journal 12 (1), 127-134, 1993
High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors
F Moreau-Gaudry, P Xia, G Jiang, NP Perelman, G Bauer, J Ellis, ...
Blood, The Journal of the American Society of Hematology 98 (9), 2664-2672, 2001
Complete disruption of autism-susceptibility genes by gene editing predominantly reduces functional connectivity of isogenic human neurons
E Deneault, SH White, DC Rodrigues, PJ Ross, M Faheem, K Zaslavsky, ...
Stem cell reports 11 (5), 1211-1225, 2018
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Artigos 1–20