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Tong Zhang
Tong Zhang
Bioinformatics Scientist
E-mail confirmado em e.ntu.edu.sg
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Ano
Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates
Y Simoni, E Becht, M Fehlings, CY Loh, SL Koo, KWW Teng, JPS Yeong, ...
Nature 557 (7706), 575-579, 2018
11112018
Amyloid β protein and Alzheimer’s disease: When computer simulations complement experimental studies
J Nasica-Labouze, PH Nguyen, F Sterpone, O Berthoumieu, NV Buchete, ...
Chemical reviews 115 (9), 3518-3563, 2015
6162015
In vivo mapping of eukaryotic RNA interactomes reveals principles of higher-order organization and regulation
JGA Aw, Y Shen, A Wilm, M Sun, XN Lim, KL Boon, S Tapsin, YS Chan, ...
Molecular cell 62 (4), 603-617, 2016
3202016
Molecular Mechanism of the Inhibition of EGCG on the Alzheimer Aβ1–42 Dimer
T Zhang, J Zhang, P Derreumaux, Y Mu
The journal of physical chemistry B 117 (15), 3993-4002, 2013
2282013
Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing
R Nahar, W Zhai, T Zhang, A Takano, AJ Khng, YY Lee, X Liu, CH Lim, ...
Nature communications 9 (1), 216, 2018
1612018
The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma
W Zhai, TKH Lim, T Zhang, ST Phang, Z Tiang, P Guan, MH Ng, JQ Lim, ...
Nature communications 8, 4565, 2017
1392017
Structures of Aβ17–42 trimers in isolation and with five small-molecule drugs using a hierarchical computational procedure
Y Chebaro, P Jiang, T Zang, Y Mu, PH Nguyen, N Mousseau, ...
The Journal of Physical Chemistry B 116 (29), 8412-8422, 2012
1112012
Atomic and Dynamic Insights into the Beneficial Effect of the 1,4-Naphthoquinon-2-yl-l-tryptophan Inhibitor on Alzheimer’s Aβ1–42 Dimer in Terms of Aggregation …
T Zhang, W Xu, Y Mu, P Derreumaux
ACS Chemical Neuroscience 5 (2), 148-159, 2014
782014
Comprehensive mapping of SARS-CoV-2 interactions in vivo reveals functional virus-host interactions
SL Yang, L DeFalco, DE Anderson, Y Zhang, JGA Aw, SY Lim, XN Lim, ...
Nature Communications 12 (1), 5113, 2021
702021
Folding atomistic proteins in explicit solvent using simulated tempering
T Zhang, PH Nguyen, J Nasica-Labouze, Y Mu, P Derreumaux
The Journal of Physical Chemistry B 119 (23), 6941-6951, 2015
422015
Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care
SL Kong, X Liu, NAM Suhaimi, KJH Koh, M Hu, DY San Lee, I Cima, ...
Oncotarget 8 (40), 68026, 2017
242017
A conserved tetrameric interaction of cry toxin helix α3 suggests a functional role for toxin oligomerization
X Lin, K Parthasarathy, W Surya, T Zhang, Y Mu, J Torres
Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (7), 1777-1784, 2014
182014
Genome-wide RNA structure changes during human neurogenesis modulate gene regulatory networks
J Wang, T Zhang, Z Yu, WT Tan, M Wen, Y Shen, FRP Lambert, RG Huber, ...
Molecular Cell 81 (23), 4942-4953. e8, 2021
162021
S100A9 induces aggregation-prone conformation in Abeta peptides: a combined experimental and simulation study
LN Zhao, T Zhang, C Zhang, C Wang, LA Morozova-Roche, LY Chew, ...
RSC advances 3 (46), 24081-24089, 2013
122013
Initial Binding of Ions to the Interhelical Loops of Divalent Ion Transporter CorA: Replica Exchange Molecular Dynamics Simulation Study
T Zhang, Y Mu
PloS one 7 (8), e43872, 2012
62012
Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing. Nat Commun. 2018; 9: 216
R Nahar, W Zhai, T Zhang, A Takano, AJ Khng, YY Lee, X Liu, CH Lim, ...
Journal of Thoracic Disease. All rights reserved. http://dx. doi. org/10 …, 0
5
Serial Passaging of Seasonal H3N2 Influenza A/Singapore/G2-31.1/2014 Virus in MDCK-SIAT1 Cells and Primary Chick Embryo Cells Generates HA D457G Mutation and Other Variants in …
DZH Aw, KK Heng, JYH Heok, XY Kong, H Chen, T Zhang, W Zhai, ...
International Journal of Molecular Sciences 23 (20), 12408, 2022
32022
The fibroblast growth factor system in cognitive disorders and dementia
W Zhai, T Zhang, Y Jin, S Huang, M Xu, J Pan
Frontiers in Neuroscience 17, 1136266, 2023
22023
Multiregion Whole Exome and Transcriptome Sequencing Defines the Genomic Spectrum of EGFR plus NSCLC and Reveals Novel Mechanisms of TKI Resistance
DSW Tan, R Nahar, A Takano, A Khng, T Zhang, TPT Koh, A Gogna, ...
JOURNAL OF THORACIC ONCOLOGY 10 (9), S796-S796, 2015
22015
Comparing genomic landscape of early stage, treatment naïve and late stage, drug resistant EGFR-mutant lung adenocarcinomas
R Nahar, YY Lee, AJ Khng, T Zhang, A Takano, X Liu, JJS Alvarez, ...
Canadian Journal of Biotechnology 1 (Special), 246, 2017
2017
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