An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers TR Bomfim, L Forny-Germano, LB Sathler, J Brito-Moreira, JC Houzel, ... The Journal of clinical investigation 122 (4), 1339-1353, 2012 | 910 | 2012 |
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models MV Lourenco, RL Frozza, GB de Freitas, H Zhang, GC Kincheski, ... Nature medicine 25 (1), 165-175, 2019 | 686 | 2019 |
TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ... Cell metabolism 18 (6), 831-843, 2013 | 393 | 2013 |
Alzheimer's disease-like pathology induced by amyloid-β oligomers in nonhuman primates L Forny-Germano, NML e Silva, AF Batista, J Brito-Moreira, M Gralle, ... Journal of Neuroscience 34 (41), 13629-13643, 2014 | 229 | 2014 |
The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non‐human primate model of Alzheimer's disease AF Batista, L Forny‐Germano, JR Clarke, NM Lyra e Silva, J Brito‐Moreira, ... The Journal of pathology 245 (1), 85-100, 2018 | 204 | 2018 |
The role of leptin and adiponectin in obesity-associated cognitive decline and Alzheimer’s disease L Forny-Germano, FG De Felice, MNN Vieira Frontiers in neuroscience 12, 430286, 2019 | 200 | 2019 |
Soluble oligomers from a non‐disease related protein mimic Aβ‐induced tau hyperphosphorylation and neurodegeneration MNN Vieira, L Forny‐Germano, LM Saraiva, A Sebollela, AMB Martinez, ... Journal of neurochemistry 103 (2), 736-748, 2007 | 98 | 2007 |
Palmitate is increased in the cerebrospinal fluid of humans with obesity and induces memory impairment in mice via pro-inflammatory TNF-α HM Melo, GSS da Silva, MR Sant’Ana, CVL Teixeira, JR Clarke, ... Cell Reports 30 (7), 2180-2194. e8, 2020 | 89 | 2020 |
Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers AF Batista, T Rody, L Forny-Germano, S Cerdeiro, M Bellio, ST Ferreira, ... Journal of neuroinflammation 18, 1-15, 2021 | 47 | 2021 |
Lyra e Silva NM, Batista AF, Brito-Moreira J, Gralle M, Boehnke SE, et al. Alzheimer's disease-like pathology induced by amyloid-beta oligomers in nonhuman primates L Forny-Germano J Neurosci 34 (41), 13629-43, 2014 | 40 | 2014 |
Understanding the link between insulin resistance and Alzheimer’s disease: Insights from animal models NML e Silva, RA Gonçalves, SE Boehnke, L Forny-Germano, DP Munoz, ... Experimental Neurology 316, 1-11, 2019 | 32 | 2019 |
Alteration in the number of neuronal and non-neuronal cells in mouse models of obesity MM Andrade, C Fernandes, L Forny-Germano, RA Gonçalves, M Gomes, ... Brain Communications 5 (2), fcad059, 2023 | 8 | 2023 |
Leptin receptor reactivation restores brain function in early-life Lepr-deficient mice C Fernandes, L Forny-Germano, MM Andrade, NM Lyra E Silva, ... Brain, awae127, 2024 | | 2024 |
Reactivation of leptin receptor alleviate the deleterious consequences of absence of leptin signaling in obese mice brain C Fernandes, L Forny-Germano, M de Andrade, M Gomes, E Fonseca, ... JOURNAL OF NEUROCHEMISTRY 162, 83-84, 2022 | | 2022 |
Alzheimer's Disease-Like Pathology Induced by Amyloid-beta Oligomers in Nonhuman Primates (vol 34, pg 13629, 2014) L Forny-Germano, NM Lyra e Silva, AF Batista, J Brito-Moreira, M Gralle, ... JOURNAL OF NEUROSCIENCE 40 (42), 8204-8204, 2020 | | 2020 |
Palmitate is increased in the cerebrospinal fluid of obese humans and induces memory impairment in mice via pro-inflammatory TNF-α HM Melo, GSS da Silva, MR Sant'Ana, C Vieira, L Teixeira, JR Clarke, ... Cell Reports, 2020 | | 2020 |
Obesity impairs cognition and leads to morphological and neurogenic alterations CF da Silva, L Forny-Germano, J Houzel, S Ferreira, J Donato, ... IBRO Reports 6, S59, 2019 | | 2019 |
O3‐05‐01: AN INFLAMMATORY PATHWAY TOWARD SYNAPSE AND COGNITIVE IMPAIRMENT TRIGGERED BY AMYLOID‐BETA OLIGOMERS: NOVEL MOLECULAR LINKS BETWEEN ALZHEIMER'S DISEASE AND DIABETES MV Lourenco, J Clarke, RL Frozza, L Forny‐Germano, W Klein, ... Alzheimer's & Dementia 10, P217-P217, 2014 | | 2014 |
O2‐09‐03: Endoplasmic reticulum stress links impaired insulin signaling and Alzheimer's disease M Lourenço, C Silva, L Sathler, L Forny‐Germano, T Bomfim, S Araújo, ... Alzheimer's & Dementia 8 (4S_Part_7), P253-P253, 2012 | | 2012 |
A nonhuman primate model of Alzheimer's disease with tangles and synapse loss triggered by Aß oligomers L Forny-Germano, NML e Silva, J Brito-Moreira, AF Batista, S Martins, ... Alzheimer's & Dementia 8 (4), P203, 2012 | | 2012 |