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Lowenna Holt
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Grb10 and Grb14: enigmatic regulators of insulin action–and more?
LJ Holt, K Siddle
Biochemical Journal 388 (2), 393-406, 2005
2062005
Mice with a Disruption of the Imprinted Grb10 Gene Exhibit Altered Body Composition, Glucose Homeostasis, and Insulin Signaling during Postnatal Life
FM Smith, LJ Holt, AS Garfield, M Charalambous, F Koumanov, M Perry, ...
Molecular and cellular biology 27 (16), 5871-5886, 2007
1592007
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
RS Depetris, J Hu, I Gimpelevich, LJ Holt, RJ Daly, SR Hubbard
Molecular cell 20 (2), 325-333, 2005
1232005
Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells
JS Berg, KK Lin, C Sonnet, NC Boles, DC Weksberg, H Nguyen, LJ Holt, ...
PloS one 6 (10), e26410, 2011
792011
Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis
LJ Holt, RJ Lyons, AS Ryan, SM Beale, A Ward, GJ Cooney, RJ Daly
Molecular endocrinology 23 (9), 1406-1414, 2009
722009
Hydrophilic and cationic latex particles for the specific extraction of nucleic acids
A Elaissari, L Holt, F Meunier, C Voisset, C Pichot, B Mandrand, C Mabilat
Journal of Biomaterials Science, Polymer Edition 10 (4), 403-420, 1999
671999
Grb10 regulates the development of fiber number in skeletal muscle
LJ Holt, N Turner, N Mokbel, S Trefely, T Kanzleiter, W Kaplan, ...
The FASEB Journal 26 (9), 3658-3669, 2012
442012
Extracellular ATP-dependent suppression of proliferation and induction of differentiation of human HL-60 leukemia cells by distinct mechanisms
AD Conigrave, L van der Weyden, L Holt, L Jiang, P Wilson, ...
Biochemical pharmacology 60 (11), 1585-1591, 2000
432000
Molecular determinants of Grb14-mediated inhibition of insulin signaling
D Goenaga, C Hampe, N Carre, K Cailliau, E Browaeys-Poly, ...
Molecular endocrinology 23 (7), 1043-1051, 2009
352009
Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation
A Rajala, RJ Daly, M Tanito, DT Allen, LJ Holt, ES Lobanova, ...
Biochemistry 48 (24), 5563-5572, 2009
332009
Adapter protein connections: the MRL and Grb7 protein families
LJ Holt, RJ Daly
Growth Factors 23 (3), 193-201, 2005
332005
Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation
N Mokbel, NJ Hoffman, CM Girgis, L Small, N Turner, RJ Daly, GJ Cooney, ...
Journal of cellular physiology 229 (11), 1753-1764, 2014
292014
Ablation of Grb10 specifically in muscle impacts muscle size and glucose metabolism in mice
LJ Holt, AE Brandon, L Small, E Suryana, E Preston, D Wilks, N Mokbel, ...
Endocrinology 159 (3), 1339-1351, 2018
212018
Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post …
K Moorwood, FM Smith, AS Garfield, M Cowley, LJ Holt, RJ Daly, A Ward
bioRxiv, 2024.01. 31.578179, 2024
2024
Analysis of the molecular mode of action of Grb14 on insulin signaling
D Goenaga, C Hampe, N Carre, K Cailliau, E Browaeys-Poly, ...
DIABETES & METABOLISM 35, A13-A14, 2009
2009
O51 Analyse moléculaire du mode d’action de Grb14 sur la signalisation de l’insuline
D Goenaga, C Hampe, N Carré, K Cailliau, E Browaeys-Poly, ...
Diabetes & Metabolism 35, A13-A14, 2009
2009
Consequences of Grb14 expression on the differentiation of adipocytary metabolism
D Goenaga, M Moldes, L Holt, J Girard, AF Burnol
DIABETES & METABOLISM 34, A27-A27, 2008
2008
O56 Conséquences de l’expression de Grb14 sur la différenciation et le métabolisme adipocytaires
D Goenaga, M Moldes, L Holt, J Girard, AF Burnol
Diabetes & Metabolism 34, H27, 2008
2008
The role of Grb10 in insulin receptor signalling
LJ Holt
University of Cambridge, 2003
2003
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Artículos 1–19