Rick Pearson

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Ross HannanProfessor Ross Hannan, Centenary Chair of Cancer Research, Deputy Dean of ResearchE-mail confirmado em anu.edu.au
Professor Rod HicksDepartment of Medicine, St Vincent's Hospital, the University of Melbourne and Department ofE-mail confirmado em mtic.net.au
Professor Tony PapenfussTheme Leader, Computational Biology, Walter and Eliza Hall Institute of MedicalE-mail confirmado em wehi.edu.au
Lawrence RothblumUniversity of Oklahoma College of medicineE-mail confirmado em ouhsc.edu
Megan AstleMonash UniversityE-mail confirmado em monash.edu
Amee J GeorgeAustralian National UniversityE-mail confirmado em anu.edu.au
Steven BozinovskiProfessor, RMIT UniversityE-mail confirmado em rmit.edu.au
Michael S. AnglesioAssistant Professor, Department of Obstetrics & Gynaecology, University of British ColumbiaE-mail confirmado em ubc.ca
Lee WongMonash UniversityE-mail confirmado em monash.edu
Joshy GeorgeDirector, Computational Sciences, Jackson Laboratory for Genomic Medicine, ConnecticutE-mail confirmado em jax.org
Nicholas VeldhuisMonash UniversityE-mail confirmado em monash.edu
Aimin XuDepartment of Medicine, Department of Pharmacology and Pharmacy, the University of Hong KongE-mail confirmado em hku.hk
Charbel DaridoGroup Leader, Peter MacCallum Cancer Centre. Senior Research Fellow, The Alfred Hospital - MonashE-mail confirmado em monash.edu
Professor Stephen JaneMonash UniversityE-mail confirmado em monash.edu
Theo MantamadiotisThe University of MelbourneE-mail confirmado em unimelb.edu.au
Cavanaugh AResearch Scientist II Weis Center for ResearchE-mail confirmado em geisinger.edu
Alexander DobrovicUniversity of Melbourne Department of SurgeryE-mail confirmado em unimelb.edu.au
Phillip J RobinsonChildren's Medical Research InstituteE-mail confirmado em cmri.org.au
Jim WoodgettSenior Scientist, Lunenfeld-Tanenbaum Research InstituteE-mail confirmado em lunenfeld.ca
Pier Paolo PandolfiDirector, Cancer Center and Cancer Research Institute, Beth Israel Deaconess Medical CenterE-mail confirmado em bidmc.harvard.edu

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Rick Pearson

Group Leader, Peter MacCallum Cancer Centre

E-mail confirmado em petermac.org

Cancer Biology


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[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations RB Pearson, BE Kemp Methods in enzymology 200, 62-81, 1991	1314	1991
Protein kinase recognition sequence motifs BE Kemp, RB Pearson Trends in biochemical sciences 15 (9), 342-346, 1990	1304	1990
Rapamycin suppresses 5′ TOP mRNA translation through inhibition of p70s6k HBJ Jefferies, S Fumagalli, PB Dennis, C Reinhard, RB Pearson, ... The EMBO journal, 1997	1211	1997
Mutation of the PIK3CA gene in ovarian and breast cancer IG Campbell, SE Russell, DYH Choong, KG Montgomery, ML Ciavarella, ... Cancer research 64 (21), 7678-7681, 2004	1168	2004
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. HC Cheng, BE Kemp, RB Pearson, AJ Smith, L Misconi, SM Van Patten, ... Journal of Biological Chemistry 261 (3), 989-992, 1986	656	1986
The Akt kinase signals directly to endothelial nitric oxide synthase BJ Michell, JE Griffiths, KI Mitchelhill, I Rodriguez-Crespo, T Tiganis, ... Current biology 9 (15), 845-848, 1999	620	1999
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53 MJ Bywater, G Poortinga, E Sanij, N Hein, A Peck, C Cullinane, M Wall, ... Cancer cell 22 (1), 51-65, 2012	593	2012
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar … KM Hannan, Y Brandenburger, A Jenkins, K Sharkey, A Cavanaugh, ... Molecular and cellular biology, 2003	587	2003
The principal target of rapamycin‐induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain. RB Pearson, PB Dennis, JW Han, NA Williamson, SC Kozma, ... The EMBO journal 14 (21), 5279-5287, 1995	556	1995
Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function K Jastrzebski, KM Hannan, EB Tchoubrieva, RD Hannan, RB Pearson Growth factors 25 (4), 209-226, 2007	318	2007
Response of BRAF-Mutant Melanoma to BRAF Inhibition Is Mediated by a Network of Transcriptional Regulators of Glycolysis TJ Parmenter, M Kleinschmidt, KM Kinross, ST Bond, J Li, MR Kaadige, ... Cancer discovery 4 (4), 423-433, 2014	304	2014
AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy MV Astle, KM Hannan, PY Ng, RS Lee, AJ George, AK Hsu, Y Haupt, ... Oncogene 31 (15), 1949-1962, 2012	294	2012
STIM1: a novel phosphoprotein located at the cell surface SSM Manji, NJ Parker, RT Williams, L Van Stekelenburg, RB Pearson, ... Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2000	293	2000
Targeting PI3 kinase/AKT/mTOR signaling in cancer K Sheppard, KM Kinross, B Solomon, RB Pearson, WA Phillips Critical Reviews™ in Oncogenesis 17 (1), 2012	291	2012
The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence. BE Kemp, RB Pearson, V Guerriero Jr, IC Bagchi, AR Means Journal of Biological Chemistry 262 (6), 2542-2548, 1987	287	1987
Substrate specificity of a multifunctional calmodulin-dependent protein kinase. RB Pearson, JR Woodgett, P Cohen, BE Kemp Journal of Biological Chemistry 260 (27), 14471-14476, 1985	284	1985
Targeting the nucleolus for cancer intervention JE Quin, JR Devlin, D Cameron, KM Hannan, RB Pearson, RD Hannan Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (6), 802-816, 2014	282	2014
Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy J Kang, N Brajanovski, KT Chan, J Xuan, RB Pearson, E Sanij Signal transduction and targeted therapy 6 (1), 323, 2021	268	2021
Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis C Darido, SR Georgy, T Wilanowski, S Dworkin, A Auden, Q Zhao, ... Cancer cell 20 (5), 635-648, 2011	263	2011
Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma O Kondrashova, M Topp, K Nesic, E Lieschke, GY Ho, MI Harrell, ... Nature communications 9 (1), 3970, 2018	255	2018

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