| Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP K Rittinger, PA Walker, JF Eccleston, K Nurmahomed, D Owen, E Laue, ... Nature 388 (6643), 693-697, 1997 | 364 | 1997 |
| The biochemistry of ras p21. RJ Grand, D Owen Biochemical Journal 279 (Pt 3), 609, 1991 | 257 | 1991 |
| Structure of Cdc42 bound to the GTPase binding domain of PAK A Morreale, M Venkatesan, HR Mott, D Owen, D Nietlispach, PN Lowe, ... Nature structural biology 7 (5), 384-388, 2000 | 247 | 2000 |
| Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK HR Mott, D Owen, D Nietlispach, PN Lowe, E Manser, L Lim, ED Laue Nature 399 (6734), 384-388, 1999 | 225 | 1999 |
| Delineation of the Cdc42/Rac-binding domain of p21-activated kinase G Thompson, D Owen, PA Chalk, PN Lowe Biochemistry 37 (21), 7885-7891, 1998 | 195 | 1998 |
| Structure of the cyclin-dependent kinase inhibitor p19Ink4d FY Luh, SJ Archer, PJ Domaille, BO Smith, D Owen, DH Brotherton, ... Nature 389 (6654), 999-1003, 1997 | 125 | 1997 |
| The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes D Owen, LJ Campbell, K Littlefield, KA Evetts, Z Li, DB Sacks, PN Lowe, ... Journal of Biological Chemistry 283 (3), 1692-1704, 2008 | 95 | 2008 |
| Residues in Cdc42 that specify binding to individual CRIB effector proteins D Owen, HR Mott, ED Laue, PN Lowe Biochemistry 39 (6), 1243-1250, 2000 | 94 | 2000 |
| Structures of Ras superfamily effector complexes: What have we learnt in two decades? HR Mott, D Owen Critical reviews in biochemistry and molecular biology 50 (2), 85-133, 2015 | 85 | 2015 |
| A novel protein expressed in mammalian cells undergoing apoptosis RJA Grand, AE Milner, T Mustoe, GD Johnson, D Owen, ML Grant, ... Experimental cell research 218 (2), 439-451, 1995 | 84 | 1995 |
| Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1) D Owen, PN Lowe, D Nietlispach, CE Brosnan, DY Chirgadze, PJ Parker, ... Journal of Biological Chemistry 278 (50), 50578-50587, 2003 | 68 | 2003 |
| The Rac1 Polybasic Region Is Required for Interaction with Its Effector PRK1*♦ R Modha, LJ Campbell, D Nietlispach, HR Buhecha, D Owen, HR Mott Journal of biological chemistry 283 (3), 1492-1500, 2008 | 67 | 2008 |
| DNA sequence analysis of the imp UV protection and mutation operon of the plasmid TP110: identification of a third gene D Lodwick, D Owen, P Strike Nucleic acids research 18 (17), 5045-5050, 1990 | 65 | 1990 |
| Structure of the sterile α motif (SAM) domain of the Saccharomyces cerevisiae mitogen-activated protein kinase pathway-modulating protein Ste50 and analysis of its interaction … SJ Grimshaw, HR Mott, KM Stott, PR Nielsen, KA Evetts, LJ Hopkins, ... Journal of Biological Chemistry 279 (3), 2192-2201, 2004 | 55 | 2004 |
| Structural Analysis of the SH3 Domain of β-PIX and Its Interaction with α-p21 Activated Kinase (PAK), HR Mott, D Nietlispach, KA Evetts, D Owen Biochemistry 44 (33), 10977-10983, 2005 | 50 | 2005 |
| Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding RB Fenwick, S Prasannan, LJ Campbell, D Nietlispach, KA Evetts, ... Biochemistry 48 (10), 2192-2206, 2009 | 48 | 2009 |
| Cdc42 in actin dynamics: An ordered pathway governed by complex equilibria and directional effector handover JR Watson, D Owen, HR Mott Small GTPases 8 (4), 237-244, 2017 | 47 | 2017 |
| The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction RB Fenwick, LJ Campbell, K Rajasekar, S Prasannan, D Nietlispach, ... Structure 18 (8), 985-995, 2010 | 44 | 2010 |
| Differential binding of RhoA, RhoB, and RhoC to protein kinase C-related kinase (PRK) isoforms PRK1, PRK2, and PRK3: PRKs have the highest affinity for RhoB CL Hutchinson, PN Lowe, SH McLaughlin, HR Mott, D Owen Biochemistry 52 (45), 7999-8011, 2013 | 43 | 2013 |
| Class IA PI3K regulatory subunits: p110-independent roles and structures M Fox, HR Mott, D Owen Biochemical Society Transactions 48 (4), 1397-1417, 2020 | 42 | 2020 |
