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AJ van der Lely
AJ van der Lely
Hoogleraar Endocrinologie, Erasmus University MC
E-mail confirmado em erasmusmc.nl
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Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
AJ Van Der Lely, M Tschop, ML Heiman, E Ghigo
Endocrine reviews 25 (3), 426-457, 2004
16332004
Octreotide
SWJ Lamberts, AJ Van der Lely, WW de Herder, LJ Hofland
new england Journal of Medicine 334 (4), 246-254, 1996
14581996
The endocrinology of aging
SWJ Lamberts, AW Van den Beld, AJ Van Der Lely
Science 278 (5337), 419-424, 1997
13211997
Treatment of acromegaly with the growth hormone–receptor antagonist pegvisomant
PJ Trainer, WM Drake, L Katznelson, PU Freda, V Herman-Bonert, ...
New England Journal of Medicine 342 (16), 1171-1177, 2000
10152000
Ghrelin
TD Müller, R Nogueiras, ML Andermann, ZB Andrews, SD Anker, ...
Molecular metabolism 4 (6), 437-460, 2015
10102015
Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans
F Broglio, E Arvat, A Benso, C Gottero, G Muccioli, M Papotti, AJ Lely, ...
The Journal of Clinical Endocrinology & Metabolism 86 (10), 5083-5083, 2001
9872001
Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist
AJ Van Der Lely, RK Hutson, PJ Trainer, GM Besser, AL Barkan, ...
The Lancet 358 (9295), 1754-1759, 2001
7782001
A clinical prediction rule for the diagnosis of coronary artery disease: validation, updating, and extension
TSS Genders, EW Steyerberg, H Alkadhi, S Leschka, L Desbiolles, ...
European heart journal 32 (11), 1316-1330, 2011
6372011
Non-acylated ghrelin counteracts the metabolic but not the neuroendocrine response to acylated ghrelin in humans
F Broglio, C Gottero, F Prodam, C Gauna, G Muccioli, M Papotti, T Abribat, ...
The Journal of Clinical Endocrinology & Metabolism 89 (6), 3062-3065, 2004
4952004
Pasireotide versus octreotide in acromegaly: a head-to-head superiority study
A Colao, MD Bronstein, P Freda, F Gu, CC Shen, M Gadelha, M Fleseriu, ...
The Journal of Clinical Endocrinology & Metabolism 99 (3), 791-799, 2014
4442014
Long-acting somatostatin analog therapy of acromegaly: a meta-analysis
PU Freda, L Katznelson, AJ Van Der Lely, CM Reyes, S Zhao, ...
The journal of clinical endocrinology & metabolism 90 (8), 4465-4473, 2005
4342005
Expert consensus document: a consensus on the medical treatment of acromegaly
A Giustina, P Chanson, D Kleinberg, MD Bronstein, DR Clemmons, ...
Nature Reviews Endocrinology 10 (4), 243-248, 2014
4332014
Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes
C Gauna, PJD Delhanty, LJ Hofland, JA Janssen, F Broglio, RJM Ross, ...
The Journal of Clinical Endocrinology & Metabolism 90 (2), 1055-1060, 2005
3972005
Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity
C Gauna, FM Meyler, J Janssen, PJD Delhanty, T Abribat, ...
The Journal of Clinical Endocrinology & Metabolism 89 (10), 5035-5042, 2004
3452004
The endocrine response to ghrelin as a function of gender in humans in young and elderly subjects
F Broglio, A Benso, C Castiglioni, C Gottero, F Prodam, S Destefanis, ...
The Journal of Clinical Endocrinology & Metabolism 88 (4), 1537-1542, 2003
3152003
Long-term safety of pegvisomant in patients with acromegaly: comprehensive review of 1288 subjects in ACROSTUDY
AJ van der Lely, BMK Biller, T Brue, M Buchfelder, E Ghigo, R Gomez, ...
The Journal of Clinical Endocrinology 97 (5), 1589-1597, 2012
3012012
Pasireotide alone or with cabergoline and ketoconazole in Cushing's disease
RA Feelders, C de Bruin, AM Pereira, JA Romijn, RT Netea-Maier, ...
New England Journal of Medicine 362 (19), 1846-1848, 2010
2952010
A consensus on the diagnosis and treatment of acromegaly comorbidities: an update
A Giustina, A Barkan, A Beckers, N Biermasz, BMK Biller, C Boguszewski, ...
The Journal of Clinical Endocrinology & Metabolism 105 (4), e937-e946, 2020
2792020
The physiology of endocrine systems with ageing
AW van den Beld, JM Kaufman, MC Zillikens, SWJ Lamberts, JM Egan, ...
The Lancet Diabetes & Endocrinology 6 (8), 647-658, 2018
2792018
Efficacy and safety of lamotrigine as add-on treatment to lithium in bipolar depression: a multicenter, double-blind, placebo-controlled trial.
MLM van der Loos, PGH Mulder, EGTM Hartong, MBJ Blom, ...
Journal of Clinical Psychiatry 70 (2), 223, 2009
2772009
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