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Marcelo Murai, PhD
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Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
J Grembecka, S He, A Shi, T Purohit, AG Muntean, RJ Sorenson, ...
Nature Chemical Biology 8 (3), 277-284, 2012
4232012
Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia
A Shi, MJ Murai, S He, G Lund, T Hartley, T Purohit, G Reddy, M Chruszcz, ...
Blood, The Journal of the American Society of Hematology 120 (23), 4461-4469, 2012
2072012
Crystal structure of menin reveals binding site for mixed lineage leukemia (MLL) protein
MJ Murai, M Chruszcz, G Reddy, J Grembecka, T Cierpicki
Journal of Biological Chemistry 286 (36), 31742-31748, 2011
952011
The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T cell development and leukemia
N Pinnell, R Yan, HJ Cho, T Keeley, MJ Murai, Y Liu, AS Alarcon, J Qin, ...
Immunity 43 (5), 870-883, 2015
652015
Periostin responds to mechanical stress and tension by activating the MTOR signaling pathway
LK Rosselli-Murai, LO Almeida, C Zagni, P Galindo-Moreno, ...
PloS one 8 (12), e83580, 2013
632013
The same site on the integrase-binding domain of lens epithelium–derived growth factor is a therapeutic target for MLL leukemia and HIV
MJ Murai, J Pollock, S He, H Miao, T Purohit, A Yokom, JL Hess, ...
Blood, The Journal of the American Society of Hematology 124 (25), 3730-3737, 2014
352014
Sequential eukaryotic translation initiation factor 5 (eIF5) binding to the charged disordered segments of eIF4G and eIF2β stabilizes the 48S preinitiation complex and promotes …
CR Singh, R Watanabe, W Chowdhury, H Hiraishi, MJ Murai, ...
Molecular and cellular biology 32 (19), 3978-3989, 2012
302012
The eukaryotic initiation factor (eIF) 4G HEAT domain promotes translation re-initiation in yeast both dependent on and independent of eIF4A mRNA helicase
R Watanabe, MJ Murai, CR Singh, S Fox, M Ii, K Asano
Journal of biological chemistry 285 (29), 21922-21933, 2010
282010
Detection of disordered regions in globular proteins using 13C‐detected NMR
FLV Gray, MJ Murai, J Grembecka, T Cierpicki
Protein Science 21 (12), 1954-1960, 2012
132012
Characterization of the C-terminal half of human juvenile myoclonic epilepsy protein EFHC1: dimer formation blocks Ca2+ and Mg2+ binding to its functional EF-hand
MJ Murai, RC Sassonia, AH Zamboni, FF Conte, D Martins-de-Souza, ...
Archives of biochemistry and biophysics 477 (1), 131-138, 2008
122008
Structural characterization of the H-NS protein from Xylella fastidiosa and its interaction with DNA
LK Rosselli-Murai, ML Sforça, RC Sassonia, AR Azzoni, MJ Murai, ...
Archives of biochemistry and biophysics 526 (1), 22-28, 2012
52012
The Machado–Joseph disease‐associated form of ataxin‐3 impacts dynamics of clathrin‐coated pits
LK Rosselli‐Murai, JG Joseph, I Lopes‐Cendes, AP Liu, MJ Murai
Cell Biology International 44 (5), 1252-1259, 2020
42020
Sequential eIF5 binding to the charged disordered segments of eIF4G and eIF2β stabilizes the 48S pre-initiation complex and promotes its shift to the initiation mode
CR Singh, R Watanabe, WQ Chowdhury, H Hiraishi, MJ Murai, ...
Molecular and Cellular Biology 32 (19), 3978-3989, 2012
42012
The Machado-Joseph disease-associated expanded form of ataxin-3: Overexpression, purification, and preliminary biophysical and structural characterization
MGG Contessotto, LK Rosselli-Murai, MCC Garcia, CLP Oliveira, ...
Protein expression and purification 152, 40-45, 2018
32018
LEDGF IBD domain represents therapeutic target for MLL leukemia and HIV
T Cierpicki, MJ Murai, J Pollock, T Purohit, S He, A Yokom, JL Hess, ...
Cancer Research 74 (19_Supplement), 3225-3225, 2014
22014
β-thalassemia intermedia in a Brazilian patient with-101 (C> T) and codon 39 (C> T) mutations
SM Sousa, L Kather, LA Peroni, K Miranda, MJ Murai, DM Albuquerque, ...
São Paulo Med J 121 (1), 28-30, 2003
22003
Inhibition of BCL10-MALT1 interaction to treat diffuse large B-cell lymphoma
H Kang, D Hu, M Murai, A Mady, B Chen, Z Nikolovska-Coleska, ...
Cancer Research 80 (16_Supplement), 3404-3404, 2020
12020
Targeting LEDGF Interactions in MLL Leukemia
T Cierpicki, S He, T Purohit, M Murai, T Hartley, J Grembecka
Blood, The Journal of the American Society of Hematology 118 (21), 2500-2500, 2011
12011
BLOCKING THE BCL10-MALT1 INTERACTION IN DIFFUSE LARGE B-CELL LYMPHOMA
L Maurer, H Kang, M Smyers, L Klei, J Cheng, M Trotta, D Hu, ...
PEDIATRIC BLOOD & CANCER 69, 2022
2022
Expressão e purificação de proteinas relacionadas a epilepsia
MJ Murai
http://www.bibliotecadigital.unicamp.br/document/?code=vtls000421581, 2007
2007
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