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Alejandro San Martín
Alejandro San Martín
Centro de Estudios Científicos & Universidad San Sebastián
E-mail confirmado em cecs.cl - Página inicial
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In vivo evidence for a lactate gradient from astrocytes to neurons
P Mächler, MT Wyss, M Elsayed, J Stobart, R Gutierrez, ...
Cell metabolism 23 (1), 94-102, 2016
5192016
A genetically encoded FRET lactate sensor and its use to detect the Warburg effect in single cancer cells
A San Martín, S Ceballo, I Ruminot, R Lerchundi, WB Frommer, LF Barros
PloS one 8 (2), e57712, 2013
3702013
Channel-mediated lactate release by K+-stimulated astrocytes
T Sotelo-Hitschfeld, MI Niemeyer, P Mächler, I Ruminot, R Lerchundi, ...
Journal of Neuroscience 35 (10), 4168-4178, 2015
2012015
Imaging mitochondrial flux in single cells with a FRET sensor for pyruvate
A San Martín, S Ceballo, F Baeza-Lehnert, R Lerchundi, R Valdebenito, ...
PloS one 9 (1), e85780, 2014
1902014
Fast and reversible stimulation of astrocytic glycolysis by K+ and a delayed and persistent effect of glutamate
CX Bittner, R Valdebenito, I Ruminot, A Loaiza, V Larenas, ...
Journal of Neuroscience 31 (12), 4709-4713, 2011
1882011
Monocarboxylate transporter 4 (MCT4) is a high affinity transporter capable of exporting lactate in high-lactate microenvironments
Y Contreras-Baeza, PY Sandoval, R Alarcón, A Galaz, F Cortés-Molina, ...
Journal of Biological Chemistry 294 (52), 20135-20147, 2019
1392019
Aerobic glycolysis in the brain: Warburg and Crabtree contra Pasteur
LF Barros, I Ruminot, A San Martín, R Lerchundi, I Fernández-Moncada, ...
Neurochemical Research 46, 15-22, 2021
602021
Small is fast: astrocytic glucose and lactate metabolism at cellular resolution
LF Barros, A San Martín, T Sotelo-Hitschfeld, R Lerchundi, ...
Frontiers in cellular neuroscience 7, 27, 2013
572013
A highly responsive pyruvate sensor reveals pathway-regulatory role of the mitochondrial pyruvate carrier MPC
R Arce-Molina, F Cortés-Molina, PY Sandoval, A Galaz, K Alegría, ...
Elife 9, e53917, 2020
542020
Single-cell imaging tools for brain energy metabolism: a review
A San Martín, T Sotelo-Hitschfeld, R Lerchundi, I Fernández-Moncada, ...
Neurophotonics 1 (1), 011004-011004, 2014
542014
Nanomolar nitric oxide concentrations quickly and reversibly modulate astrocytic energy metabolism
A San Martín, R Arce-Molina, A Galaz, G Pérez-Guerra, LF Barros
Journal of Biological Chemistry 292 (22), 9432-9438, 2017
502017
Tacrolimus causes a blockage of protein secretion which reinforces its immunosuppressive activity and also explains some of its toxic side-effects
MC Rauch, A San Martín, D Ojeda, C Quezada, M Salas, JG Cárcamo, ...
Transplant Immunology 22 (1-2), 72-81, 2009
452009
Near‐critical GLUT1 and neurodegeneration
LF Barros, A San Martin, I Ruminot, PY Sandoval, I Fernández‐Moncada, ...
Journal of Neuroscience Research 95 (11), 2267-2274, 2017
382017
Fluid brain glycolysis: limits, speed, location, moonlighting, and the fates of glycogen and lactate
LF Barros, A San Martín, I Ruminot, PY Sandoval, F Baeza-Lehnert, ...
Neurochemical Research 45, 1328-1334, 2020
192020
Visualizing physiological parameters in cells and tissues using genetically encoded indicators for metabolites
A San Martín, R Arce-Molina, C Aburto, F Baeza-Lehnert, LF Barros, ...
Free Radical Biology and Medicine 182, 34-58, 2022
162022
MitoToxy assay: A novel cell-based method for the assessment of metabolic toxicity in a multiwell plate format using a lactate FRET nanosensor, Laconic
Y Contreras-Baeza, S Ceballo, R Arce-Molina, PY Sandoval, K Alegría, ...
PLoS One 14 (10), e0224527, 2019
152019
Imaging of the lactate/pyruvate ratio using a genetically encoded forster resonance energy transfer indicator
A Galaz, F Cortés-Molina, R Arce-Molina, I Romero-Gómez, GA Mardones, ...
Analytical Chemistry 92 (15), 10643-10650, 2020
112020
Single-fluorophore indicator to explore cellular and sub-cellular lactate dynamics
C Aburto, A Galaz, A Bernier, PY Sandoval, S Holtheuer-Gallardo, ...
ACS sensors 7 (11), 3278-3286, 2022
82022
Functional interaction between bicarbonate transporters and carbonic anhydrase modulates lactate uptake into mouse cardiomyocytes
J Peetz, LF Barros, A San Martín, HM Becker
Pflügers Archiv-European Journal of Physiology 467, 1469-1480, 2015
62015
Enlightening brain energy metabolism
LF Barros, I Ruminot, PY Sandoval, A San Martín
Neurobiology of Disease 184, 106211, 2023
32023
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