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Matheus de Freitas Silva
Matheus de Freitas Silva
Universidade Federal de Alfenas
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The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones
M de Freitas Silva, L Pruccoli, F Morroni, G Sita, F Seghetti, C Viegas Jr, ...
Molecules 23 (7), 1803, 2018
892018
Multi-target directed drugs as a modern approach for drug design towards Alzheimer's disease: an update
M de Freitas Silva, KST Dias, VS Gontijo, CJC Ortiz, J Viegas
Current medicinal chemistry 25 (29), 3491-3525, 2018
832018
Molecular hybridization as a tool in the design of multi-target directed drug candidates for neurodegenerative diseases
VS Gontijo, FPD Viegas, CJC Ortiz, M de Freitas Silva, CM Damasio, ...
Current neuropharmacology 18 (5), 348-407, 2020
792020
Donepezil: an important prototype to the design of new drug candidates for Alzheimer’s disease
M Cecilia Rodrigues Simoes, F Pereira Dias Viegas, M Soares Moreira, ...
Mini reviews in medicinal chemistry 14 (1), 2-19, 2014
732014
Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer …
FPD Viegas, M de Freitas Silva, MD da Rocha, MR Castelli, MM Riquiel, ...
European journal of medicinal chemistry 147, 48-65, 2018
562018
Synthetic resveratrol-curcumin hybrid derivative inhibits mitosis progression in estrogen positive MCF-7 breast cancer cells
M de Freitas Silva, LF Coelho, IM Guirelli, RM Pereira, GÁ Ferreira-Silva, ...
Toxicology in Vitro 50, 75-85, 2018
402018
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer’s Disease
M de Freitas Silva, E Tardelli Lima, L Pruccoli, NG Castro, ...
Molecules 25 (14), 3165, 2020
152020
Design of Multi-target Directed Ligands as a Modern Approach for the Development of Innovative Drug Candidates for Alzheimer’s Disease
CJC Ortiz, M de Freitas Silva, VS Gontijo, FPD Viegas, KST Dias, ...
Humana Press, 2018
92018
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease
SM Vaz, M de Freitas Silva, GRR Franco, MJR Guimarães, FMR da Silva, ...
Bioorganic & Medicinal Chemistry 71, 116952, 2022
62022
Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation
CC Ortiz, M de Freitas Silva, L Pruccoli, NF Nadur, LL de Azevedo, ...
RSC Medicinal Chemistry, 2022
32022
New multifunctional AChE inhibitor drug prototypes protect against Aβ-induced memory deficit
PMQ Bellozi, AC Campos, FPD Viegas, MF Silva, RP Machado, SM Vaz, ...
Neurological Sciences 41 (2), 451-455, 2020
12020
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