| MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity E Giovannetti, N Funel, GJ Peters, M Del Chiaro, LA Erozenci, E Vasile, ... Cancer research 70 (11), 4528-4538, 2010 | 530 | 2010 |
| Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer JH Hwang, J Voortman, E Giovannetti, SM Steinberg, LG Leon, YT Kim, ... PloS one 5 (5), e10630, 2010 | 359 | 2010 |
| Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells C Granchi, S Roy, C Giacomelli, M Macchia, T Tuccinardi, A Martinelli, ... Journal of medicinal chemistry 54 (6), 1599-1612, 2011 | 254 | 2011 |
| Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia M Maftouh, A Avan, R Sciarrillo, C Granchi, LG Leon, R Rani, N Funel, ... British journal of cancer 110 (1), 172-182, 2014 | 173 | 2014 |
| High-Throughput MicroRNA (miRNAs) Arrays Unravel the Prognostic Role of MiR-211 in Pancreatic Cancer. PGJ Giovannetti E, van der Velde A, Funel N, Vasile E PloS One 7 (11), e49145, 2012 | 93 | 2012 |
| Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol EL Bonifazi, C Ríos-Luci, LG León, G Burton, JM Padrón, RI Misico Bioorganic & medicinal chemistry 18 (7), 2621-2630, 2010 | 93 | 2010 |
| Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer D Massihnia, A Avan, N Funel, M Maftouh, A Van Krieken, C Granchi, ... Journal of Hematology & Oncology 10, 1-17, 2017 | 86 | 2017 |
| Abietane diterpenoids from Salvia pachyphylla and S. clevelandii with cytotoxic activity against human cancer cell lines IC Guerrero, LS Andrés, LG León, RP Machín, JM Padrón, JG Luis, ... Journal of natural products 69 (12), 1803-1805, 2006 | 79 | 2006 |
| Development of bioluminescent chick chorioallantoic membrane (CAM) models for primary pancreatic cancer cells: A platform for drug testing M Rovithi, A Avan, N Funel, LG Leon, VE Gomez, T Wurdinger, ... Scientific reports 7 (1), 44686, 2017 | 78 | 2017 |
| Correlation of cytidine deaminase polymorphisms and activity with clinical outcome in gemcitabine-/platinum-treated advanced non-small-cell lung cancer patients C Tibaldi, E Giovannetti, M Tiseo, LG Leon, A D'incecco, N Loosekoot, ... Annals of oncology 23 (3), 670-677, 2012 | 66 | 2012 |
| Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol CR Pungitore, LG León, C García, VS Martín, CE Tonn, JM Padrón Bioorganic & medicinal chemistry letters 17 (5), 1332-1335, 2007 | 56 | 2007 |
| Heterometallic platinum (II) compounds with β-aminoethylferrocenes: synthesis, electrochemical behaviour and anticancer activity D Nieto, AM González-Vadillo, S Bruña, CJ Pastor, C Ríos-Luci, LG León, ... Dalton Transactions 41 (2), 432-441, 2012 | 55 | 2012 |
| Association between DNA-repair polymorphisms and survival in pancreatic cancer patients treated with combination chemotherapy E Giovannetti, P Pacetti, M Reni, LG Leon, A Mambrini, E Vasile, ... Pharmacogenomics 12 (12), 1641-1652, 2011 | 55 | 2011 |
| Preclinical emergence of vandetanib as a potent antitumour agent in mesothelioma: molecular mechanisms underlying its synergistic interaction with pemetrexed and carboplatin E Giovannetti, PA Zucali, YG Assaraf, LG Leon, K Smid, C Alecci, ... British journal of cancer 105 (10), 1542-1553, 2011 | 54 | 2011 |
| Molecular simplification in bioactive molecules: formal synthesis of (+)-muconin FR Pinacho Crisóstomo, R Carrillo, LG León, T Martín, JM Padrón, ... The Journal of Organic Chemistry 71 (6), 2339-2345, 2006 | 53 | 2006 |
| Antiproliferative and structure activity relationships of Amaryllidaceae alkaloids JC Cedrón, ÁG Ravelo, LG León, JM Padrón, A Estévez-Braun Molecules 20 (8), 13854-13863, 2015 | 52 | 2015 |
| β-Lapachone analogs with enhanced antiproliferative activity C Ríos-Luci, EL Bonifazi, LG Leon, JC Montero, G Burton, A Pandiella, ... European journal of medicinal chemistry 53, 264-274, 2012 | 50 | 2012 |
| Reactivity and Biological Properties of a Series of Cytotoxic PtI2(amine)2 Complexes, Either cis or trans Configured L Messori, L Cubo, C Gabbiani, A Alvarez-Valdes, E Michelucci, ... Inorganic Chemistry 51 (3), 1717-1726, 2012 | 48 | 2012 |
| NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor E Galvani, J Sun, LG Leon, R Sciarrillo, RS Narayan, RTT Sjin, K Lee, ... Oncotarget 6 (40), 42717, 2015 | 46 | 2015 |
| Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model LJA Toonen, M Overzier, MM Evers, LG Leon, SAJ van der Zeeuw, H Mei, ... Molecular Neurodegeneration 13, 1-18, 2018 | 45 | 2018 |
Elisa GiovannettiAssociate Professor - UHD - Amsterdam UMC (VUmc) & FPS, PisaVerified email at vumc.nl
