| Diffusible, nonfibrillar ligands derived from Aβ1–42 are potent central nervous system neurotoxins MP Lambert, AK Barlow, BA Chromy, C Edwards, R Freed, M Liosatos, ... Proceedings of the National Academy of Sciences 95 (11), 6448-6453, 1998 | 4593 | 1998 |
| Aβ oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease PN Lacor, MC Buniel, PW Furlow, AS Clemente, PT Velasco, M Wood, ... Journal of Neuroscience 27 (4), 796-807, 2007 | 1514 | 2007 |
| Alzheimer's disease-affected brain: presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss Y Gong, L Chang, KL Viola, PN Lacor, MP Lambert, CE Finch, GA Krafft, ... Proceedings of the National Academy of Sciences 100 (18), 10417-10422, 2003 | 1421 | 2003 |
| Synaptic targeting by Alzheimer's-related amyloid β oligomers PN Lacor, MC Buniel, L Chang, SJ Fernandez, Y Gong, KL Viola, ... Journal of Neuroscience 24 (45), 10191-10200, 2004 | 1245 | 2004 |
| Aβ oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine FG De Felice, PT Velasco, MP Lambert, K Viola, SJ Fernandez, ... Journal of Biological Chemistry 282 (15), 11590-11601, 2007 | 1083 | 2007 |
| Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Aβ oligomers FG De Felice, MNN Vieira, TR Bomfim, H Decker, PT Velasco, ... Proceedings of the National Academy of Sciences 106 (6), 1971-1976, 2009 | 774 | 2009 |
| Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus HW Wang, JF Pasternak, H Kuo, H Ristic, MP Lambert, B Chromy, ... Brain research 924 (2), 133-140, 2002 | 770 | 2002 |
| The amyloid-β oligomer hypothesis: beginning of the third decade EN Cline, MA Bicca, KL Viola, WL Klein Journal of Alzheimer's Disease 64 (s1), S567-S610, 2018 | 747 | 2018 |
| Self-Assembly of Aβ1-42 into Globular Neurotoxins BA Chromy, RJ Nowak, MP Lambert, KL Viola, L Chang, PT Velasco, ... Biochemistry 42 (44), 12749-12760, 2003 | 685 | 2003 |
| Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis KL Viola, WL Klein Acta neuropathologica 129, 183-206, 2015 | 649 | 2015 |
| Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies MP Lambert, KL Viola, BA Chromy, L Chang, TE Morgan, J Yu, DL Venton, ... Journal of neurochemistry 79 (3), 595-605, 2001 | 489 | 2001 |
| Monoclonal antibodies that target pathological assemblies of Aβ MP Lambert, PT Velasco, L Chang, KL Viola, S Fernandez, PN Lacor, ... Journal of neurochemistry 100 (1), 23-35, 2007 | 434 | 2007 |
| Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease KL Viola, J Sbarboro, R Sureka, M De, MA Bicca, J Wang, S Vasavada, ... Nature nanotechnology 10 (1), 91-98, 2015 | 180 | 2015 |
| Anti-ADDL antibodies and uses thereof W Klein, G Krafft, M Lambert, K Viola, B Chromy, Y Gong, L Chang, ... US Patent App. 10/166,856, 2003 | 136 | 2003 |
| Why Alzheimer's is a disease of memory: The attack on synapses by Aß oligomers (ADDLs) KL Viola, PT Velasco, WL Klein The Journal of nutrition, health and aging 12, S51-S57, 2008 | 122 | 2008 |
| Anti-ADDL antibodies and uses thereof P Acton, Z An, AJ Bett, R Breese, L Chang, EC Dodson, G Kinney, W Klein, ... US Patent 7,780,963, 2010 | 93 | 2010 |
| Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers J Pitt, KC Wilcox, V Tortelli, LP Diniz, MS Oliveira, C Dobbins, XW Yu, ... Molecular Biology of the Cell 28 (20), 2623-2636, 2017 | 77 | 2017 |
| Brain transit and ameliorative effects of intranasally delivered anti-amyloid-β oligomer antibody in 5XFAD mice C Xiao, FJ Davis, BC Chauhan, KL Viola, PN Lacor, PT Velasco, WL Klein, ... Journal of Alzheimer's Disease 35 (4), 777-788, 2013 | 72 | 2013 |
| Amyloid beta oligomers target to extracellular and intracellular neuronal synaptic proteins in Alzheimer's disease Y Ding, J Zhao, X Zhang, S Wang, KL Viola, FE Chow, Y Zhang, C Lippa, ... Frontiers in neurology 10, 1140, 2019 | 60 | 2019 |
| Synapse-binding subpopulations of Aβ oligomers sensitive to peptide assembly blockers and scFv antibodies PT Velasco, MC Heffern, A Sebollela, IA Popova, PN Lacor, KB Lee, ... ACS chemical neuroscience 3 (11), 972-981, 2012 | 58 | 2012 |
