Folate-targeted chemotherapy CP Leamon, JA Reddy Advanced drug delivery reviews 56 (8), 1127-1141, 2004 | 804 | 2004 |
The folate receptor as a rational therapeutic target for personalized cancer treatment YG Assaraf, CP Leamon, JA Reddy Drug Resistance Updates 17 (4-6), 89-95, 2014 | 379 | 2014 |
Folate-mediated targeting of therapeutic and imaging agents to cancers JA Reddy, PS Low Critical Reviews™ in Therapeutic Drug Carrier Systems 15 (6), 1998 | 348 | 1998 |
Synthesis and biological evaluation of EC20: a new folate-derived, 99mTc-based radiopharmaceutical CP Leamon, MA Parker, IR Vlahov, LC Xu, JA Reddy, M Vetzel, ... Bioconjugate chemistry 13 (6), 1200-1210, 2002 | 334 | 2002 |
Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery CM Paulos, JA Reddy, CP Leamon, MJ Turk, PS Low Molecular pharmacology 66 (6), 1406-1414, 2004 | 307 | 2004 |
Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs MJ Turk, JA Reddy, JA Chmielewski, PS Low Biochimica et Biophysica Acta (BBA)-Biomembranes 1559 (1), 56-68, 2002 | 245 | 2002 |
Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate JA Reddy, R Dorton, E Westrick, A Dawson, T Smith, LC Xu, M Vetzel, ... Cancer research 67 (9), 4434-4442, 2007 | 231 | 2007 |
Folate-targeted, cationic liposome-mediated gene transfer into disseminated peritoneal tumors JA Reddy, C Abburi, H Hofland, SJ Howard, I Vlahov, P Wils, CP Leamon Gene therapy 9 (22), 1542-1550, 2002 | 231 | 2002 |
Enhanced folate receptor mediated gene therapy using a novel pH-sensitive lipid formulation JA Reddy, PS Low Journal of Controlled Release 64 (1-3), 27-37, 2000 | 219 | 2000 |
Targeting therapeutic and imaging agents to folate receptor positive tumors JA Reddy, VM Allagadda, CP Leamon Current pharmaceutical biotechnology 6 (2), 131-150, 2005 | 207 | 2005 |
Folate-targeted gene transfer in vivo HEJ Hofland, C Masson, S Iginla, I Osetinsky, JA Reddy, CP Leamon, ... Molecular Therapy 5 (6), 739-744, 2002 | 174 | 2002 |
Preclinical evaluation of 99mTc-EC20 for imaging folate receptor–positive tumors JA Reddy, LC Xu, N Parker, M Vetzel, CP Leamon Journal of Nuclear Medicine 45 (5), 857-866, 2004 | 156 | 2004 |
Expression and Functional Characterization of the β-Isoform of the Folate Receptor on CD34+ Cells JA Reddy, LS Haneline, EF Srour, AC Antony, DW Clapp, PS Low Blood, The Journal of the American Society of Hematology 93 (11), 3940-3948, 1999 | 150 | 1999 |
Vitamin receptor binding drug delivery conjugates IR Vlahov, CP Leamon, MA Parker, SJ Howard, HK Santhapuram, ... US Patent 7,601,332, 2009 | 148 | 2009 |
Preclinical antitumor activity of a novel folate-targeted dual drug conjugate CP Leamon, JA Reddy, IR Vlahov, E Westrick, A Dawson, R Dorton, ... Molecular pharmaceutics 4 (5), 659-667, 2007 | 144 | 2007 |
Optimization of folate-conjugated liposomal vectors for folate receptor-mediated gene therapy JA Reddy, D Dean, MD Kennedy, PS Low Journal of pharmaceutical sciences 88 (11), 1112-1118, 1999 | 143 | 1999 |
Synthesis and biological evaluation of EC72: a new folate-targeted chemotherapeutic CP Leamon, JA Reddy, IR Vlahov, M Vetzel, N Parker, JS Nicoson, LC Xu, ... Bioconjugate chemistry 16 (4), 803-811, 2005 | 139 | 2005 |
Comparative preclinical activity of the folate‐targeted Vinca alkaloid conjugates EC140 and EC145 CP Leamon, JA Reddy, IR Vlahov, E Westrick, N Parker, JS Nicoson, ... International journal of cancer 121 (7), 1585-1592, 2007 | 126 | 2007 |
Folate targeting enables durable and specific antitumor responses from a therapeutically null tubulysin B analogue CP Leamon, JA Reddy, M Vetzel, R Dorton, E Westrick, N Parker, Y Wang, ... Cancer research 68 (23), 9839-9844, 2008 | 123 | 2008 |
Folate receptor–specific antitumor activity of EC131, a folate-maytansinoid conjugate JA Reddy, E Westrick, HKR Santhapuram, SJ Howard, ML Miller, M Vetzel, ... Cancer Research 67 (13), 6376-6382, 2007 | 109 | 2007 |