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Joseph Reddy
Joseph Reddy
Astellas Pharma US
E-mail confirmado em astellas.com
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Folate-targeted chemotherapy
CP Leamon, JA Reddy
Advanced drug delivery reviews 56 (8), 1127-1141, 2004
8042004
The folate receptor as a rational therapeutic target for personalized cancer treatment
YG Assaraf, CP Leamon, JA Reddy
Drug Resistance Updates 17 (4-6), 89-95, 2014
3792014
Folate-mediated targeting of therapeutic and imaging agents to cancers
JA Reddy, PS Low
Critical Reviews™ in Therapeutic Drug Carrier Systems 15 (6), 1998
3481998
Synthesis and biological evaluation of EC20: a new folate-derived, 99mTc-based radiopharmaceutical
CP Leamon, MA Parker, IR Vlahov, LC Xu, JA Reddy, M Vetzel, ...
Bioconjugate chemistry 13 (6), 1200-1210, 2002
3342002
Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery
CM Paulos, JA Reddy, CP Leamon, MJ Turk, PS Low
Molecular pharmacology 66 (6), 1406-1414, 2004
3072004
Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs
MJ Turk, JA Reddy, JA Chmielewski, PS Low
Biochimica et Biophysica Acta (BBA)-Biomembranes 1559 (1), 56-68, 2002
2452002
Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate
JA Reddy, R Dorton, E Westrick, A Dawson, T Smith, LC Xu, M Vetzel, ...
Cancer research 67 (9), 4434-4442, 2007
2312007
Folate-targeted, cationic liposome-mediated gene transfer into disseminated peritoneal tumors
JA Reddy, C Abburi, H Hofland, SJ Howard, I Vlahov, P Wils, CP Leamon
Gene therapy 9 (22), 1542-1550, 2002
2312002
Enhanced folate receptor mediated gene therapy using a novel pH-sensitive lipid formulation
JA Reddy, PS Low
Journal of Controlled Release 64 (1-3), 27-37, 2000
2192000
Targeting therapeutic and imaging agents to folate receptor positive tumors
JA Reddy, VM Allagadda, CP Leamon
Current pharmaceutical biotechnology 6 (2), 131-150, 2005
2072005
Folate-targeted gene transfer in vivo
HEJ Hofland, C Masson, S Iginla, I Osetinsky, JA Reddy, CP Leamon, ...
Molecular Therapy 5 (6), 739-744, 2002
1742002
Preclinical evaluation of 99mTc-EC20 for imaging folate receptor–positive tumors
JA Reddy, LC Xu, N Parker, M Vetzel, CP Leamon
Journal of Nuclear Medicine 45 (5), 857-866, 2004
1562004
Expression and Functional Characterization of the β-Isoform of the Folate Receptor on CD34+ Cells
JA Reddy, LS Haneline, EF Srour, AC Antony, DW Clapp, PS Low
Blood, The Journal of the American Society of Hematology 93 (11), 3940-3948, 1999
1501999
Vitamin receptor binding drug delivery conjugates
IR Vlahov, CP Leamon, MA Parker, SJ Howard, HK Santhapuram, ...
US Patent 7,601,332, 2009
1482009
Preclinical antitumor activity of a novel folate-targeted dual drug conjugate
CP Leamon, JA Reddy, IR Vlahov, E Westrick, A Dawson, R Dorton, ...
Molecular pharmaceutics 4 (5), 659-667, 2007
1442007
Optimization of folate-conjugated liposomal vectors for folate receptor-mediated gene therapy
JA Reddy, D Dean, MD Kennedy, PS Low
Journal of pharmaceutical sciences 88 (11), 1112-1118, 1999
1431999
Synthesis and biological evaluation of EC72: a new folate-targeted chemotherapeutic
CP Leamon, JA Reddy, IR Vlahov, M Vetzel, N Parker, JS Nicoson, LC Xu, ...
Bioconjugate chemistry 16 (4), 803-811, 2005
1392005
Comparative preclinical activity of the folate‐targeted Vinca alkaloid conjugates EC140 and EC145
CP Leamon, JA Reddy, IR Vlahov, E Westrick, N Parker, JS Nicoson, ...
International journal of cancer 121 (7), 1585-1592, 2007
1262007
Folate targeting enables durable and specific antitumor responses from a therapeutically null tubulysin B analogue
CP Leamon, JA Reddy, M Vetzel, R Dorton, E Westrick, N Parker, Y Wang, ...
Cancer research 68 (23), 9839-9844, 2008
1232008
Folate receptor–specific antitumor activity of EC131, a folate-maytansinoid conjugate
JA Reddy, E Westrick, HKR Santhapuram, SJ Howard, ML Miller, M Vetzel, ...
Cancer Research 67 (13), 6376-6382, 2007
1092007
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