Pierre Hainaut
Pierre Hainaut
Professor, Cancer Biology, University Grenoble Alpes and Director, Institute for Advanced
E-mail confirmado em univ-grenoble-alpes.fr - Página inicial
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Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database
A Petitjean, E Mathe, S Kato, C Ishioka, SV Tavtigian, P Hainaut, M Olivier
Human mutation 28 (6), 622-629, 2007
18052007
TP53 mutations in human cancers: origins, consequences, and clinical use
M Olivier, M Hollstein, P Hainaut
Cold Spring Harbor perspectives in biology 2 (1), a001008, 2010
15822010
The IARC TP53 database: new online mutation analysis and recommendations to users
M Olivier, R Eeles, M Hollstein, MA Khan, CC Harris, P Hainaut
Human mutation 19 (6), 607-614, 2002
14072002
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
RJ Hung, JD McKay, V Gaborieau, P Boffetta, M Hashibe, D Zaridze, ...
Nature 452 (7187), 633-637, 2008
13632008
p53 and human cancer: the first ten thousand mutations
P Hainaut, M Hollstein
Advances in cancer research 77, 81-137, 1999
12581999
Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers
GP Pfeifer, MF Denissenko, M Olivier, N Tretyakova, SS Hecht, P Hainaut
Oncogene 21 (48), 7435-7451, 2002
11902002
A global view of hepatocellular carcinoma: trends, risk, prevention and management
JD Yang, P Hainaut, GJ Gores, A Amadou, A Plymoth, LR Roberts
Nature reviews Gastroenterology & hepatology 16 (10), 589-604, 2019
11022019
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes
A Petitjean, MIW Achatz, AL Borresen-Dale, P Hainaut, M Olivier
Oncogene 26 (15), 2157-2165, 2007
9362007
Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype
M Olivier, DE Goldgar, N Sodha, H Ohgaki, P Kleihues, P Hainaut, ...
Cancer research 63 (20), 6643-6650, 2003
5762003
The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer.
M Olivier, A Langer, P Carrieri, J Bergh, S Klaar, J Eyfjord, C Theillet, ...
Clinical cancer research 12 (4), 1157-1167, 2006
5652006
IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools
P Hainaut, T Hernandez, A Robinson, P Rodriguez-Tome, T Flores, ...
Nucleic acids research 26 (1), 205-213, 1998
5471998
Circulating free DNA in plasma or serum as biomarker of carcinogenesis: practical aspects and biological significance
E Gormally, E Caboux, P Vineis, P Hainaut
Mutation Research/Reviews in Mutation Research 635 (2-3), 105-117, 2007
5182007
Redox modulation of p53 conformation and sequence-specific DNA binding in vitro
P Hainaut, J Milner
Cancer research 53 (19), 4469-4473, 1993
5071993
WHO classification tumor of the digestive system
SR Hamilton
Tumours of the Oesophagus, 2000
5032000
Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations: a nested case-control study
M Jenab, HB Bueno-de-Mesquita, P Ferrari, FJB van Duijnhoven, T Norat, ...
Bmj 340, 2010
4962010
PRIMA-1 reactivates mutant p53 by covalent binding to the core domain
JMR Lambert, P Gorzov, DB Veprintsev, M Söderqvist, D Segerbäck, ...
Cancer cell 15 (5), 376-388, 2009
4912009
Patterns of p53 G→ T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke
P Hainaut, GP Pfeifer
Carcinogenesis 22 (3), 367-374, 2001
4832001
NAFLD in Asia—as common and important as in the West
GC Farrell, VWS Wong, S Chitturi
Nature reviews Gastroenterology & hepatology 10 (5), 307-318, 2013
4362013
Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective study
P Vineis, L Airoldi, F Veglia, L Olgiati, R Pastorelli, H Autrup, A Dunning, ...
Bmj 330 (7486), 277, 2005
3962005
Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects
P Hainaut, T Soussi, B Shomer, M Hollstein, M Greenblatt, E Hovig, ...
Nucleic acids research 25 (1), 151-157, 1997
3891997
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