| CD14 and toll-like receptors 2 and 4 are required for fibrillar Aβ-stimulated microglial activation EG Reed-Geaghan, JC Savage, AG Hise, GE Landreth Journal of Neuroscience 29 (38), 11982-11992, 2009 | 628 | 2009 |
| Microglia across the lifespan: from origin to function in brain development, plasticity and cognition TL Tay, JC Savage, CW Hui, K Bisht, MÈ Tremblay The Journal of physiology 595 (6), 1929-1945, 2017 | 523 | 2017 |
| Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry AM Bond, MJW VanGompel, EA Sametsky, MF Clark, JC Savage, ... Nature neuroscience 12 (8), 1020-1027, 2009 | 421 | 2009 |
| Evidence for impaired amyloid β clearance in Alzheimer's disease KR Wildsmith, M Holley, JC Savage, R Skerrett, GE Landreth Alzheimer's research & therapy 5, 1-6, 2013 | 265 | 2013 |
| Neuronal hyperactivity disturbs ATP microgradients, impairs microglial motility, and reduces phagocytic receptor expression triggering apoptosis/microglial phagocytosis uncoupling O Abiega, S Beccari, I Diaz-Aparicio, A Nadjar, S Layé, Q Leyrolle, ... PLoS biology 14 (5), e1002466, 2016 | 203 | 2016 |
| Morphology of microglia across contexts of health and disease JC Savage, M Carrier, MÈ Tremblay Microglia: methods and protocols, 13-26, 2019 | 150 | 2019 |
| Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease JC Savage, T Jay, E Goduni, C Quigley, MM Mariani, T Malm, ... Journal of Neuroscience 35 (16), 6532-6543, 2015 | 149 | 2015 |
| Ultrastructural evidence of microglial heterogeneity in Alzheimer’s disease amyloid pathology H El Hajj, JC Savage, K Bisht, M Parent, L Vallières, S Rivest, ... Journal of neuroinflammation 16, 1-19, 2019 | 86 | 2019 |
| A brief history of microglial ultrastructure: distinctive features, phenotypes, and functions discovered over the past 60 years by electron microscopy JC Savage, K Picard, F González-Ibáñez, MÈ Tremblay Frontiers in Immunology 9, 358783, 2018 | 76 | 2018 |
| Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses JL Bolton, AK Short, S Othy, CL Kooiker, M Shao, BG Gunn, J Beck, X Bai, ... Cell reports 38 (13), 2022 | 74 | 2022 |
| Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington’s disease pathology JC Savage, MK St-Pierre, M Carrier, H El Hajj, SW Novak, MG Sanchez, ... Journal of neuroinflammation 17, 1-18, 2020 | 70 | 2020 |
| Synaptic Loss in Alzheimer's Disease: Mechanistic Insights Provided by Two-Photon in vivo Imaging of Transgenic Mouse Models J Subramanian, JC Savage, MÈ Tremblay Frontiers in cellular neuroscience 14, 592607, 2020 | 69 | 2020 |
| Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells ME Tremblay, I Zhang, K Bisht, JC Savage, C Lecours, M Parent, ... Journal of Neuroinflammation 13, 1-18, 2016 | 63 | 2016 |
| Microglial and peripheral immune priming is partially sexually dimorphic in adolescent mouse offspring exposed to maternal high-fat diet M Bordeleau, C Lacabanne, L Fernández de Cossío, N Vernoux, ... Journal of Neuroinflammation 17, 1-28, 2020 | 58 | 2020 |
| Environmental stimuli shape microglial plasticity in glioma S Garofalo, A Porzia, F Mainiero, S Di Angelantonio, B Cortese, B Basilico, ... Elife 6, e33415, 2017 | 55 | 2017 |
| Microglial ultrastructure in the hippocampus of a lipopolysaccharide-induced sickness mouse model JC Savage, MK St-Pierre, CW Hui, ME Tremblay Frontiers in Neuroscience 13, 481363, 2019 | 47 | 2019 |
| Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice K Picard, K Bisht, S Poggini, S Garofalo, MT Golia, B Basilico, F Abdallah, ... Brain, behavior, and immunity 97, 423-439, 2021 | 38 | 2021 |
| Maternal high-fat diet modifies myelin organization, microglial interactions, and results in social memory and sensorimotor gating deficits in adolescent mouse offspring M Bordeleau, LF de Cossío, C Lacabanne, JC Savage, N Vernoux, ... Brain, Behavior, & Immunity-Health 15, 100281, 2021 | 32 | 2021 |
| Correlative light and electron microscopy to study microglial interactions with β-amyloid plaques K Bisht, H El Hajj, JC Savage, MG Sánchez, MÈ Tremblay JoVE (Journal of Visualized Experiments), e54060, 2016 | 32 | 2016 |
| Blocking immune cell infiltration of the central nervous system to tame Neuroinflammation in Amyotrophic lateral sclerosis S Garofalo, G Cocozza, G Bernardini, J Savage, M Raspa, E Aronica, ... Brain, behavior, and immunity 105, 1-14, 2022 | 27 | 2022 |
