An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression RSJ Asis Palazon, Petros A. Tyrakis, David Macias, Pedro Velica, Helene ... Cancer Cell 32 (5), 669-683, 2017 | 410 | 2017 |
S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate PA Tyrakis, A Palazon, D Macias, KL Lee, AT Phan, P Veliça, J You, ... Nature 540 (7632), 236-241, 2016 | 358 | 2016 |
Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection AT Phan, AL Doedens, A Palazon, PA Tyrakis, KP Cheung, RS Johnson, ... Immunity 45 (5), 1024-1037, 2016 | 200 | 2016 |
A Late‐Stage Intermediate in Salinomycin Biosynthesis Is Revealed by Specific Mutation in the Biosynthetic Gene Cluster ME Yurkovich, PA Tyrakis, H Hong, Y Sun, M Samborskyy, K Kamiya, ... ChemBioChem 13 (1), 66-71, 2012 | 80 | 2012 |
Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects CF PA Tyrakis, ME Yurkovich, M Sciacovelli, EK Papachristou, HR Bridges, E ... Cell Reports 21 (4), 1036-1047, 2017 | 75 | 2017 |
The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia J Sim, AS Cowburn, A Palazon, B Madhu, PA Tyrakis, D Macías, ... Cell Metabolism 27 (4), 898-913. e7, 2018 | 73 | 2018 |
Mycobacterium tuberculosis dihydrofolate reductase reveals two conformational states and a possible low affinity mechanism to antifolate drugs MVB Dias, P Tyrakis, RR Domingues, AFP Leme, TL Blundell Structure 22 (1), 94-103, 2014 | 36 | 2014 |
Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis CE Evans, A Palazon, J Sim, PA Tyrakis, A Prodger, X Lu, S Chan, ... Biology Open, 2017 | 21 | 2017 |
Using a Fragment-Based Approach to Identify Alternative Chemical Scaffolds Targeting Dihydrofolate Reductase from Mycobacterium tuberculosis JA Ribeiro, A Hammer, GA Libreros-Zuniga, SM Chavez-Pacheco, ... ACS Infectious Diseases 6 (8), 2192-2201, 2020 | 16 | 2020 |
Using a fragment-based approach to identify novel chemical scaffolds targeting the dihydrofolate reductase (DHFR) from Mycobacterium tuberculosis JA Ribeiro, A Hammer, GAL Zuniga, SM Chavez-Pacheco, P Tyrakis, ... bioRxiv, 2020 | 1 | 2020 |
Methods Of T-Lymphocyte Expansion RS Johnson, A PALAZON, PA Tyrakis US Patent App. 15/772,782, 2019 | | 2019 |
Identification of new molecules that bind to the enzyme dihydrofolate reductase of Mycobacterium tuberculosis. GA Libreros-Zúñiga, JA Ribeiro, A Hammer, SM Chávez-Pacheco, ... Biomédica 39 (Suppl. 4), 28-29, 2019 | | 2019 |
Methods of t-lymphocyte expansion R Johnson, GFDA Palazon, PA TYRAKIS | | 2017 |