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Alexandra Nicaise
Alexandra Nicaise
E-mail confirmado em cam.ac.uk
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Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis
AM Nicaise, LJ Wagstaff, CM Willis, C Paisie, H Chandok, P Robson, ...
Proceedings of the National Academy of Sciences 116 (18), 9030-9039, 2019
1752019
The neural stem cell secretome and its role in brain repair
CM Willis, AM Nicaise, L Peruzzotti-Jametti, S Pluchino
Brain research 1729, 146615, 2020
972020
Astrocyte support for oligodendrocyte differentiation can be conveyed via extracellular vesicles but diminishes with age
CM Willis, AM Nicaise, ER Bongarzone, M Givogri, CR Reiter, O Heintz, ...
Scientific reports 10 (1), 828, 2020
642020
iPS-derived neural progenitor cells from PPMS patients reveal defect in myelin injury response
AM Nicaise, E Banda, RM Guzzo, K Russomanno, W Castro-Borrero, ...
Experimental neurology 288, 114-121, 2017
642017
Stem cells of the aging brain
AM Nicaise, CM Willis, SJ Crocker, S Pluchino
Frontiers in Aging Neuroscience 12, 247, 2020
602020
Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis
CM Willis, AM Nicaise, A Menoret, JK Ryu, AS Mendiola, ER Jellison, ...
Proceedings of the National Academy of Sciences 116 (21), 10488-10493, 2019
422019
TIMP-1 promotes oligodendrocyte differentiation through receptor-mediated signaling
AM Nicaise, KM Johnson, CM Willis, RM Guzzo, SJ Crocker
Molecular neurobiology 56, 3380-3392, 2019
392019
A refined bead-free method to identify astrocytic exosomes in primary glial cultures and blood plasma
CM Willis, A Ménoret, ER Jellison, AM Nicaise, AT Vella, SJ Crocker
Frontiers in neuroscience, 255266, 2017
362017
Harnessing the neural stem cell secretome for regenerative neuroimmunology
CM Willis, AM Nicaise, R Hamel, V Pappa, L Peruzzotti-Jametti, ...
Frontiers in cellular neuroscience 14, 590960, 2020
352020
Stem cell therapies for progressive multiple sclerosis
JA Smith, AM Nicaise, RB Ionescu, R Hamel, L Peruzzotti-Jametti, ...
Frontiers in cell and developmental biology 9, 696434, 2021
332021
Aberrant production of tenascin-C in globoid cell leukodystrophy alters psychosine-induced microglial functions
KI Claycomb, PN Winokur, KM Johnson, AM Nicaise, AW Giampetruzzi, ...
Journal of Neuropathology & Experimental Neurology 73 (10), 964-974, 2014
332014
The role of neural stem cells in regulating glial scar formation and repair
AM Nicaise, A D’Angelo, RB Ionescu, G Krzak, CM Willis, S Pluchino
Cell and Tissue Research, 1-16, 2022
312022
A microglial hypothesis of globoid cell leukodystrophy pathology
AM Nicaise, ER Bongarzone, SJ Crocker
Journal of neuroscience research 94 (11), 1049-1061, 2016
312016
Systemic TLR2 tolerance enhances central nervous system remyelination
NJ Wasko, MH Kulak, D Paul, AM Nicaise, ST Yeung, FC Nichols, ...
Journal of Neuroinflammation 16, 1-15, 2019
282019
Soluble factors influencing the neural stem cell niche in brain physiology, inflammation, and aging
CM Willis, AM Nicaise, G Krzak, RB Ionescu, V Pappa, A D'Angelo, ...
Experimental neurology 355, 114124, 2022
222022
NSCs: sentinel cells of the brain
S Pluchino, AM Nicaise
Cell Stem Cell 28 (2), 177-179, 2021
52021
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy
PA Sutter, A Ménoret, ER Jellison, AM Nicaise, AM Bradbury, AT Vella, ...
Journal of Experimental Medicine 220 (9), 2023
22023
Integrative transcriptomic and metabolic analyses of the mammalian hibernating brain identifies a key role for succinate dehydrogenase in ischemic tolerance
JD Bernstock, CM Willis, ME Garcia-Segura, E Gaude, D Anni, Y Lee, ...
bioRxiv, 2023.03. 29.534718, 2023
22023
Integrative single-cell analysis of neural stem/progenitor cells reveals epigenetically dysregulated interferon response in progressive multiple sclerosis
B Park, AM Nicaise, D Tsitsipatis, L Pirvan, P Prasad, ...
bioRxiv, 2024.02. 09.579648, 2024
12024
Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis
RB Ionescu, AM Nicaise, JA Reisz, EC Williams, P Prasad, ...
bioRxiv, 2024.01. 16.575826, 2024
12024
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