| Increased localization of APP‐C99 in mitochondria‐associated ER membranes causes mitochondrial dysfunction in Alzheimer disease M Pera, D Larrea, C Guardia‐Laguarta, J Montesinos, KR Velasco, ... The EMBO journal 36 (22), 3356-3371, 2017 | 198 | 2017 |
| The Alzheimer's disease‐associated C99 fragment of APP regulates cellular cholesterol trafficking J Montesinos, M Pera, D Larrea, C Guardia‐Laguarta, RR Agrawal, ... The EMBO journal 39 (20), e103791, 2020 | 90 | 2020 |
| MFN2 mutations in Charcot–Marie–Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics D Larrea, M Pera, A Gonnelli, R Quintana–Cabrera, HO Akman, ... Human molecular genetics 28 (11), 1782-1800, 2019 | 89 | 2019 |
| Functional dissection of the conjugative coupling protein TrwB HD De Paz, D Larrea, S Zunzunegui, C Dehio, F de la Cruz, M Llosa Journal of bacteriology 192 (11), 2655-2669, 2010 | 54 | 2010 |
| PPARγ deacetylation dissociates thiazolidinedione’s metabolic benefits from its adverse effects MJ Kraakman, Q Liu, J Postigo-Fernandez, R Ji, N Kon, D Larrea, ... The Journal of Clinical Investigation 128 (6), 2600-2612, 2018 | 44 | 2018 |
| APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice E Area-Gomez, D Larrea, M Pera, RR Agrawal, DN Guilfoyle, L Pirhaji, ... Scientific Reports 10 (1), 4277, 2020 | 40 | 2020 |
| Lipidomics study of plasma from patients suggest that ALS and PLS are part of a continuum of motor neuron disorders E Area-Gomez, D Larrea, T Yun, Y Xu, J Hupf, F Zandkarimi, RB Chan, ... Scientific reports 11 (1), 13562, 2021 | 39 | 2021 |
| A translocation motif in relaxase TrwC specifically affects recruitment by its conjugative type IV secretion system A Alperi, D Larrea, E Fernández-González, C Dehio, EL Zechner, M Llosa Journal of bacteriology 195 (22), 4999-5006, 2013 | 39 | 2013 |
| Role of E-cadherin in epithelial architecture maintenance MF Izaguirre, D Larrea, JF Adur, JE Diaz-Zamboni, NB Vicente, ... Cell communication & adhesion 17 (1), 1-12, 2010 | 32 | 2010 |
| The silence of the fats: A MAM’s story about Alzheimer RR Agrawal, J Montesinos, D Larrea, E Area-Gomez, M Pera Neurobiology of Disease 145, 105062, 2020 | 27 | 2020 |
| Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure J Fan, W Du, JY Kim-Muller, J Son, T Kuo, D Larrea, C Garcia, T Kitamoto, ... Molecular metabolism 34, 97-111, 2020 | 26 | 2020 |
| MAM and C99, key players in the pathogenesis of Alzheimer’s disease M Pera, J Montesinos, D Larrea, RR Agrawal, KR Velasco, ... International Review of Neurobiology 154, 235-278, 2020 | 16 | 2020 |
| Structural independence of conjugative coupling protein TrwB from its type IV secretion machinery D Larrea, HD De Paz, I Arechaga, F de la Cruz, M Llosa Plasmid 70 (1), 146-153, 2013 | 16 | 2013 |
| Assessing mitochondrial respiratory bioenergetics in whole cells and isolated organelles by microplate respirometry RR Agrawal, KA Tamucci, M Pera, D Larrea Methods in Cell Biology 155, 157-180, 2020 | 7 | 2020 |
| Substrate translocation involves specific lysine residues of the central channel of the conjugative coupling protein TrwB D Larrea, HD De Paz, I Matilla, DL Guzmán-Herrador, G Lasso, ... Molecular genetics and genomics 292 (5), 1037-1049, 2017 | 6 | 2017 |
| Alzheimer’s-associated upregulation of mitochondria-associated ER membranes after traumatic brain injury RR Agrawal, D Larrea, Y Xu, L Shi, H Zirpoli, LG Cummins, V Emmanuele, ... Cellular and Molecular Neurobiology 43 (5), 2219-2241, 2023 | 5 | 2023 |
| MFN2-dependent recruitment of ATAT1 coordinates mitochondria motility with alpha-tubulin acetylation and is disrupted in CMT2A A Kumar, D Larrea, ME Pero, P Infante, M Conenna, GJ Shin, WB Grueber, ... bioRxiv, 2023.03. 15.532838, 2023 | 1 | 2023 |
| The C99 fragment of APP regulates cholesterol trafficking: Molecular and cell biology/APP/Abeta/amyloid J Montesinos, M Pera, D Larrea, C Guardia‐Laguarta, E Area‐Gomez Alzheimer's & Dementia 16, e038479, 2020 | 1 | 2020 |
| APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice T Nuriel, D Larrea, DN Guilfoyle, L Pirhaji, K Shannon, H Arain, A Ashok, ... bioRxiv, 482422, 2018 | 1 | 2018 |
| La interfase molecular entre los sistemas de secreción tipo IV y sus sustratos D Larrea | 1 | 2013 |
