The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment NM Ayoub, AB Siddique, HY Ebrahim, MM Mohyeldin, KA El Sayed European journal of pharmacology 810, 100-111, 2017 | 71 | 2017 |
Prodigiosins from a marine sponge-associated actinomycete attenuate HCl/ethanol-induced gastric lesion via antioxidant and anti-inflammatory mechanisms MS Abdelfattah, MIY Elmallah, HY Ebrahim, RS Almeer, RMA Eltanany, ... PLoS One 14 (6), e0216737, 2019 | 61 | 2019 |
Rutin as a novel c-Met inhibitory lead for the control of triple negative breast malignancies HE Elsayed, HY Ebrahim, MM Mohyeldin, AB Siddique, AM Kamal, ... Nutrition and cancer 69 (8), 1256-1271, 2017 | 57 | 2017 |
Norstictic Acid Inhibits Breast Cancer Cell Proliferation, Migration, Invasion, and In Vivo Invasive Growth Through Targeting C‐Met HY Ebrahim, HE Elsayed, MM Mohyeldin, MR Akl, J Bhattacharjee, ... Phytotherapy Research 30 (4), 557-566, 2016 | 55 | 2016 |
The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer … MS Mady, MM Mohyeldin, HY Ebrahim, HE Elsayed, WE Houssen, ... Bioorganic & medicinal chemistry 24 (2), 113-122, 2016 | 54 | 2016 |
Novel liquid-liquid extraction and self-emulsion methods for simplified isolation of extra-virgin olive oil phenolics with emphasis on (-)-oleocanthal and its oral anti-breast … AB Siddique, H Ebrahim, M Mohyeldin, M Qusa, Y Batarseh, A Fayyad, ... PloS one 14 (4), e0214798, 2019 | 49 | 2019 |
Araguspongine C induces autophagic death in breast cancer cells through suppression of c-Met and HER2 receptor tyrosine kinase signaling MR Akl, NM Ayoub, HY Ebrahim, MM Mohyeldin, KY Orabi, AI Foudah, ... Marine drugs 13 (1), 288-311, 2015 | 46 | 2015 |
PEGylated γ-tocotrienol isomer of vitamin E: Synthesis, characterization, in vitro cytotoxicity, and oral bioavailability A Abu-Fayyad, F Behery, AA Sallam, S Alqahtani, H Ebrahim, ... European Journal of Pharmaceutics and Biopharmaceutics 96, 185-195, 2015 | 32 | 2015 |
Discovery, optimization, and pharmacophore modeling of oleanolic acid and analogues as breast cancer cell migration and invasion inhibitors through targeting Brk/Paxillin/Rac1 axis HE Elsayed, MR Akl, HY Ebrahim, AA Sallam, EG Haggag, AM Kamal, ... Chemical biology & drug design 85 (2), 231-243, 2015 | 32 | 2015 |
3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells MR Akl, HE Elsayed, HY Ebrahim, EG Haggag, AM Kamal, KA El Sayed European Journal of Pharmacology 740, 209-217, 2014 | 32 | 2014 |
(−)-Oleocanthal combined with lapatinib treatment synergized against HER-2 positive breast cancer in vitro and in vivo AB Siddique, HY Ebrahim, MR Akl, NM Ayoub, AA Goda, MM Mohyeldin, ... Nutrients 11 (2), 412, 2019 | 30 | 2019 |
Synthesis, anticancer evaluation and molecular docking studies of new heterocycles linked to sulfonamide moiety as novel human topoisomerase types I and II poisons AH Halawa, WE Elgammal, SM Hassan, AH Hassan, HS Nassar, ... Bioorganic Chemistry 98, 103725, 2020 | 27 | 2020 |
Usnic acid benzylidene analogues as potent mechanistic target of rapamycin inhibitors for the control of breast malignancies HY Ebrahim, MR Akl, HE Elsayed, RA Hill, KA El Sayed Journal of natural products 80 (4), 932-952, 2017 | 26 | 2017 |
The marine-derived sipholenol A-4-O-3′, 4′-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling MR Akl, AI Foudah, HY Ebrahim, SA Meyer, KAE Sayed Marine drugs 12 (4), 2282-2304, 2014 | 24 | 2014 |
The oleocanthal-based homovanillyl sinapate as a novel c-Met inhibitor MM Mohyeldin, MR Akl, HY Ebrahim, AM Dragoi, S Dykes, JA Cardelli, ... Oncotarget 7 (22), 32247, 2016 | 22 | 2016 |
Rationally designed hecogenin thiosemicarbazone analogs as novel MEK inhibitors for the control of breast malignancies HE Elsayed, HY Ebrahim, EG Haggag, AM Kamal, KA El Sayed Bioorganic & Medicinal Chemistry 25 (24), 6297-6312, 2017 | 21 | 2017 |
The tobacco cembranoid (1S, 2E, 4S, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol as a novel angiogenesis inhibitory lead for the control of breast malignancies MM Hailat, HY Ebrahim, MM Mohyeldin, AA Goda, AB Siddique, ... Bioorganic & Medicinal Chemistry 25 (15), 3911-3921, 2017 | 20 | 2017 |
(1S,2E,4S,7E,11E)-2,7,11-Cembratriene-4,6-diol semisynthetic analogs as novel c-Met inhibitors for the control of c-Met-dependent breast malignancies HY Ebrahim, MM Mohyeldin, MM Hailat, KA El Sayed Bioorganic & medicinal chemistry 24 (22), 5748-5761, 2016 | 19 | 2016 |
Discovery of novel antiangiogenic marine natural product scaffolds HY Ebrahim, KA El Sayed Marine Drugs 14 (3), 57, 2016 | 18 | 2016 |
Growth inhibition and apoptotic effect of pine extract and abietic acid on MCF-7 breast cancer cells via alteration of multiple gene expressions using in vitro approach H Haffez, S Osman, HY Ebrahim, ZA Hassan Molecules 27 (1), 293, 2022 | 17 | 2022 |