| The evolution of high-throughput experimentation in pharmaceutical development and perspectives on the future SM Mennen, C Alhambra, CL Allen, M Barberis, S Berritt, TA Brandt, ... Organic Process Research & Development 23 (6), 1213-1242, 2019 | 335 | 2019 |
| Selective Hydrogen Atom Abstraction through Induced Bond Polarization: Direct α‐Arylation of Alcohols through Photoredox, HAT, and Nickel Catalysis J Twilton, M Christensen, DA DiRocco, RT Ruck, IW Davies, ... Angewandte Chemie International Edition 57 (19), 5369-5373, 2018 | 169 | 2018 |
| Data-science driven autonomous process optimization M Christensen, LPE Yunker, F Adedeji, F Häse, LM Roch, T Gensch, ... Communications Chemistry 4 (1), 112, 2021 | 145 | 2021 |
| Enantioselective synthesis of an HCV NS5a antagonist IK Mangion, C Chen, H Li, P Maligres, Y Chen, M Christensen, R Cohen, ... Organic letters 16 (9), 2310-2313, 2014 | 78 | 2014 |
| Olympus: a benchmarking framework for noisy optimization and experiment planning F Häse, M Aldeghi, RJ Hickman, LM Roch, M Christensen, E Liles, ... Machine Learning: Science and Technology 2 (3), 035021, 2021 | 76 | 2021 |
| Automation isn't automatic M Christensen, LPE Yunker, P Shiri, T Zepel, PL Prieto, S Grunert, F Bork, ... Chemical science 12 (47), 15473-15490, 2021 | 67 | 2021 |
| Expedited selection of NMR chiral solvating agents for determination of enantiopurity L Yang, T Wenzel, RT Williamson, M Christensen, W Schafer, CJ Welch ACS Central Science 2 (5), 332-340, 2016 | 62 | 2016 |
| Asymmetric synthesis of letermovir using a novel phase-transfer-catalyzed aza-Michael reaction GR Humphrey, SM Dalby, T Andreani, B Xiang, MR Luzung, ZJ Song, ... Organic Process Research & Development 20 (6), 1097-1103, 2016 | 57 | 2016 |
| Enantioselective Synthesis of α-Methyl-β-cyclopropyldihydrocinnamates M Christensen, A Nolting, M Shevlin, M Weisel, PE Maligres, J Lee, ... The Journal of Organic Chemistry 81 (3), 824-830, 2016 | 46 | 2016 |
| Development of an automated kinetic profiling system with online HPLC for reaction optimization M Christensen, F Adedeji, S Grosser, K Zawatzky, Y Ji, J Liu, JA Jurica, ... Reaction Chemistry & Engineering 4 (9), 1555-1558, 2019 | 42 | 2019 |
| Discovery of 2-pyridinone aminals: a prodrug strategy to advance a second generation of HIV-1 integrase strand transfer inhibitors IT Raheem, AM Walji, D Klein, JM Sanders, DA Powell, P Abeywickrema, ... Journal of medicinal chemistry 58 (20), 8154-8165, 2015 | 36 | 2015 |
| P2Et Phosphazene: A Mild, Functional Group Tolerant Base for Soluble, Room Temperature Pd-Catalyzed C–N, C–O, and C–C Cross-Coupling Reactions A Buitrago Santanilla, M Christensen, LC Campeau, IW Davies, ... Organic letters 17 (13), 3370-3373, 2015 | 35 | 2015 |
| P2Et Phosphazene: A Mild, Functional Group Tolerant Base for Soluble, Room Temperature Pd-Catalyzed CN, CO, and CC Cross-Coupling Reactions. AB Santanilla, M Christensen, LC Campeau, IW Davies, SD Dreher Org. Lett. 17 (13), 3370-3373, 2015 | 34 | 2015 |
| Selective functionalization of complex heterocycles via an automated strong base screening platform SB Boga, M Christensen, N Perrotto, SW Krska, S Dreher, MT Tudge, ... Reaction Chemistry & Engineering 2 (4), 446-450, 2017 | 33 | 2017 |
| Design and synthesis of novel, selective GPR40 AgoPAMs CW Plummer, MJ Clements, H Chen, M Rajagopalan, H Josien, ... ACS Medicinal Chemistry Letters 8 (2), 221-226, 2017 | 30 | 2017 |
| Metal-and acid-free C–H formylation of nitrogen heterocycles: using trioxane as an aldehyde equivalent enabled by an organic-soluble oxidant JM Ganley, M Christensen, Y Lam, Z Peng, AR Angeles, CS Yeung Organic letters 20 (18), 5752-5756, 2018 | 27 | 2018 |
| Electrochemical recycling of adenosine triphosphate in biocatalytic reaction cascades S Ruccolo, G Brito, M Christensen, T Itoh, K Mattern, K Stone, ... Journal of the American Chemical Society 144 (49), 22582-22588, 2022 | 20 | 2022 |
| Perspectives on the Past, Present, and Future of High-Throughput Experimentation S Berritt, M Christensen, MJ Johansson, SW Krska, SG Newman, ... The Power of High-Throughput Experimentation: General Topics and Enabling …, 2022 | 1 | 2022 |
| Dynamic sampling in autonomous process optimization M Christensen, Y Xu, EE Kwan, M Di Maso, Y Ji, M Reibarkh, A Sun, ... Chemical Science, 2024 | | 2024 |
| The development and applications of autonomous process optimization systems MD Christensen University of British Columbia, 2022 | | 2022 |
