| CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control JN Min, RA Whaley, NE Sharpless, P Lockyer, AL Portbury, C Patterson Molecular and cellular biology 28 (12), 4018-4025, 2008 | 292 | 2008 |
| Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins HH Li, MS Willis, P Lockyer, N Miller, H McDonough, DJ Glass, ... The Journal of clinical investigation 117 (11), 3211-3223, 2007 | 281 | 2007 |
| LRP1-dependent endocytic mechanism governs the signaling output of the bmp system in endothelial cells and in angiogenesis X Pi, CE Schmitt, L Xie, AL Portbury, Y Wu, P Lockyer, LA Dyer, M Moser, ... Circulation research 111 (5), 564-574, 2012 | 79 | 2012 |
| CHIP protects against cardiac pressure overload through regulation of AMPK JC Schisler, CE Rubel, C Zhang, P Lockyer, DM Cyr, C Patterson The Journal of clinical investigation 123 (8), 2013 | 78 | 2013 |
| The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun HH Li, J Du, YN Fan, ML Zhang, DP Liu, L Li, P Lockyer, EY Kang, ... The American journal of pathology 178 (3), 1043-1058, 2011 | 68 | 2011 |
| Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ H Mao, P Lockyer, L Li, CM Ballantyne, C Patterson, L Xie, X Pi Nature communications 8 (1), 14960, 2017 | 56 | 2017 |
| MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition L Xu, CC Yates, P Lockyer, L Xie, A Bevilacqua, J He, C Lander, ... Journal of molecular and cellular cardiology 77, 86-101, 2014 | 50 | 2014 |
| Carboxyl terminus of Hsp70‐interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise MS Willis, JN Min, S Wang, H McDonough, P Lockyer, KM Wadosky, ... Cell biochemistry and function 31 (8), 724-735, 2013 | 50 | 2013 |
| LRP1 regulates retinal angiogenesis by inhibiting PARP-1 activity and endothelial cell proliferation H Mao, P Lockyer, WHD Townley-Tilson, L Xie, X Pi Arteriosclerosis, thrombosis, and vascular biology 36 (2), 350-360, 2016 | 47 | 2016 |
| Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1‐mediated gene expression in vivo MS Willis, KM Wadosky, JE Rodríguez, JC Schisler, P Lockyer, EG Hilliard, ... Cell biochemistry and function 32 (1), 39-50, 2014 | 46 | 2014 |
| NADPH oxidase–generated reactive oxygen species are required for stromal cell–derived factor-1α–stimulated angiogenesis X Pi, L Xie, AL Portbury, S Kumar, P Lockyer, X Li, C Patterson Arteriosclerosis, Thrombosis, and Vascular Biology 34 (9), 2023-2032, 2014 | 44 | 2014 |
| Minireview: Won’t get fooled again: the nonmetabolic roles of peroxisome proliferator-activated receptors (PPARs) in the heart P Lockyer, JC Schisler, C Patterson, MS Willis Molecular Endocrinology 24 (6), 1111-1119, 2010 | 43 | 2010 |
| Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis X Pi, P Lockyer, LA Dyer, JC Schisler, B Russell, S Carey, DT Sweet, ... Arteriosclerosis, thrombosis, and vascular biology 32 (9), 2214-2222, 2012 | 41 | 2012 |
| BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice N Patel, P Masaratana, J Diaz-Castro, GO Latunde-Dada, A Qureshi, ... Journal of Biological Chemistry 287 (6), 4099-4106, 2012 | 35 | 2012 |
| LRP1-dependent BMPER signaling regulates lipopolysaccharide-induced vascular inflammation P Lockyer, H Mao, Q Fan, L Li, LY Yu-Lee, NT Eissa, C Patterson, L Xie, ... Arteriosclerosis, thrombosis, and vascular biology 37 (8), 1524-1535, 2017 | 30 | 2017 |
| Efficient In Vivo Selection of a Novel Tumor-Associated Peptide from a Phage Display Library AN Veleva, DB Nepal, CB Frederick, J Schwab, P Lockyer, H Yuan, ... Molecules 16 (1), 900-914, 2011 | 26 | 2011 |
| Development of a new positron emission tomography tracer for targeting tumor angiogenesis: Synthesis, small animal imaging, and radiation dosimetry C Patterson, CB Frederick, H Yuan, LA Dyer, P Lockyer, DS Lalush, ... Molecules 18 (5), 5594-5610, 2013 | 24 | 2013 |
| BMPER promotes epithelial-mesenchymal transition in the developing cardiac cushions L Dyer, P Lockyer, Y Wu, A Saha, C Cyr, M Moser, X Pi, C Patterson PLoS One 10 (9), e0139209, 2015 | 21 | 2015 |
| BMPER regulates cardiomyocyte size and vessel density in vivo MS Willis, LA Dyer, R Ren, P Lockyer, I Moreno-Miralles, JC Schisler, ... Cardiovascular Pathology 22 (3), 228-240, 2013 | 21 | 2013 |
| Recombinant human interleukin-11 treatment enhances collateral vessel growth after femoral artery ligation J Aitsebaomo, S Srivastava, H Zhang, S Jha, Z Wang, S Winnik, ... Arteriosclerosis, thrombosis, and vascular biology 31 (2), 306-312, 2011 | 19 | 2011 |
