Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial SE Kasner, B Swaminathan, P Lavados, M Sharma, K Muir, R Veltkamp, ... The Lancet Neurology 17 (12), 1053-1060, 2018 | 183 | 2018 |
Probing the aurone scaffold against Plasmodium falciparum: Design, synthesis and antimalarial activity MP Carrasco, AS Newton, L Gonçalves, A Góis, M Machado, J Gut, ... European journal of medicinal chemistry 80, 523-534, 2014 | 86 | 2014 |
A review of antimalarial plants used in traditional medicine in communities in Portuguese-speaking countries: Brazil, Mozambique, Cape Verde, Guinea-Bissau, São Tomé and … JRA Silva, AS Ramos, M Machado, DF de Moura, Z Neto, ... Memorias do Instituto Oswaldo Cruz 106, 142-158, 2011 | 76 | 2011 |
Alkaloids from Narcissus poeticus cv. Pink Parasol of various structural types and their biological activity M Šafratová, A Hošťálková, D Hulcová, K Breiterová, V Hrabcová, ... Archives of pharmacal research 41, 208-218, 2018 | 69 | 2018 |
Inhibition of Plasmodium liver infection by ivermectin AM Mendes, IS Albuquerque, M Machado, J Pissarra, P Meireles, ... Antimicrobial Agents and Chemotherapy 61 (2), 10.1128/aac. 02005-16, 2017 | 66 | 2017 |
Primaquine–pyrimidine hybrids: synthesis and dual-stage antiplasmodial activity H Kaur, M Machado, C de Kock, P Smith, K Chibale, M Prudencio, ... European journal of medicinal chemistry 101, 266-273, 2015 | 56 | 2015 |
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in … K Singh, J Okombo, C Brunschwig, F Ndubi, L Barnard, C Wilkinson, ... Journal of medicinal chemistry 60 (4), 1432-1448, 2017 | 52 | 2017 |
Primaquine hybrids as promising antimycobacterial and antimalarial agents K Pavić, I Perković, Š Pospíšilová, M Machado, D Fontinha, M Prudêncio, ... European journal of medicinal chemistry 143, 769-779, 2018 | 45 | 2018 |
Evaluation of artemether-lumefantrine efficacy in the treatment of uncomplicated malaria and its association with pfmdr1, pfatpase6 and K13-propeller … K Kiaco, J Teixeira, M Machado, V do Rosário, D Lopes Malaria journal 14, 1-10, 2015 | 41 | 2015 |
An extended DNA-free intranuclear compartment organizes centrosome microtubules in malaria parasites CS Simon, C Funaya, J Bauer, Y Voβ, M Machado, A Penning, ... Life science alliance 4 (11), 2021 | 40 | 2021 |
Enantiopure Indolizinoindolones with in vitro activity against blood‐and liver‐stage malaria parasites NAL Pereira, Â Monteiro, M Machado, J Gut, E Molins, MJ Perry, ... ChemMedChem 10 (12), 2080-2089, 2015 | 38 | 2015 |
Primaquine-based ionic liquids as a novel class of antimalarial hits R Ferraz, J Noronha, F Murtinheira, F Nogueira, M Machado, M Prudêncio, ... RSC advances 6 (61), 56134-56138, 2016 | 33 | 2016 |
Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability R Capela, J Magalhaes, D Miranda, M Machado, M Sanches-Vaz, ... European Journal of Medicinal Chemistry 149, 69-78, 2018 | 32 | 2018 |
Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents TS Macedo, L Colina-Vegas, M Da Paixao, M Navarro, BC Barreto, ... Parasitology 143 (12), 1543-1556, 2016 | 32 | 2016 |
Treatment of Plasmodium chabaudi Parasites with Curcumin in Combination with Antimalarial Drugs: Drug Interactions and Implications on the Ubiquitin … Z Neto, M Machado, A Lindeza, V do Rosário, ML Gazarini, D Lopes Journal of parasitology research 2013, 2013 | 32 | 2013 |
Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection F Arez, SP Rebelo, D Fontinha, D Simão, TR Martins, M Machado, ... ACS infectious diseases 5 (11), 1831-1842, 2019 | 31 | 2019 |
A Plasmodium berghei sporozoite-based vaccination platform against human malaria AM Mendes, M Machado, N Gonçalves-Rosa, IJ Reuling, L Foquet, ... npj Vaccines 3 (1), 33, 2018 | 31 | 2018 |
Bioluminescence Method for In Vitro Screening of Plasmodium Transmission-Blocking Compounds R Azevedo, M Markovic, M Machado, B Franke-Fayard, AM Mendes, ... Antimicrobial Agents and Chemotherapy 61 (6), 10.1128/aac. 02699-16, 2017 | 31 | 2017 |
Reinvestigating old pharmacophores: are 4-aminoquinolines and tetraoxanes potential two-stage antimalarials? N Terzic, J Konstantinović, M Tot, J Burojevic, O Djurkovic-Djakovic, ... Journal of Medicinal Chemistry 59 (1), 264-281, 2016 | 31 | 2016 |
Platinum(ii)–chloroquine complexes are antimalarial agents against blood and liver stages by impairing mitochondrial function TS Macedo, W Villarreal, CC Couto, DRM Moreira, M Navarro, ... Metallomics 9 (11), 1548-1561, 2017 | 29 | 2017 |