Johannes Schlachetzki
Johannes Schlachetzki
UCSD
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An environment-dependent transcriptional network specifies human microglia identity
D Gosselin, D Skola, NG Coufal, IR Holtman, JCM Schlachetzki, E Sajti, ...
Science 356 (6344), 2017
5362017
Frontotemporal dementia and its subtypes: a genome-wide association study
R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ...
The Lancet Neurology 13 (7), 686-699, 2014
2352014
Unbiased and mobile gait analysis detects motor impairment in Parkinson's disease
J Klucken, J Barth, P Kugler, J Schlachetzki, T Henze, F Marxreiter, Z Kohl, ...
PloS one 8 (2), e56956, 2013
1992013
Wearable sensors objectively measure gait parameters in Parkinson’s disease
JCM Schlachetzki, J Barth, F Marxreiter, J Gossler, Z Kohl, S Reinfelder, ...
PloS one 12 (10), e0183989, 2017
1512017
Brain cell type–specific enhancer–promoter interactome maps and disease-risk association
A Nott, IR Holtman, NG Coufal, JCM Schlachetzki, M Yu, R Hu, CZ Han, ...
Science 366 (6469), 1134-1139, 2019
1422019
Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity
W Xiang, JCM Schlachetzki, S Helling, JC Bussmann, M Berlinghof, ...
Molecular and Cellular Neuroscience 54, 71-83, 2013
1292013
Granulocyte‐colony stimulating factor is neuroprotective in a model of Parkinson's disease
K Meuer, C Pitzer, P Teismann, C Krüger, B Göricke, R Laage, P Lingor, ...
Journal of neurochemistry 97 (3), 675-686, 2006
1242006
Microglial activation in Alzheimer's disease
J Schlachetzki, M Hull
Current Alzheimer Research 6 (6), 554-563, 2009
962009
Microbiome–microglia connections via the gut–brain axis
R Abdel-Haq, JCM Schlachetzki, CK Glass, SK Mazmanian
Journal of Experimental Medicine 216 (1), 41-59, 2019
912019
Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain Kupffer cell identity
M Sakai, TD Troutman, JS Seidman, Z Ouyang, NJ Spann, Y Abe, KM Ego, ...
Immunity 51 (4), 655-670. e8, 2019
822019
Oligodendroglia and myelin in neurodegenerative diseases: more than just bystanders?
B Ettle, JCM Schlachetzki, J Winkler
Molecular neurobiology 53 (5), 3046-3062, 2016
792016
Studying neurodegenerative diseases in culture models
J Schlachetzki, SW Saliba, ACP Oliveira
Brazilian Journal of Psychiatry 35, S92-S100, 2013
742013
Alpha-synuclein activates BV2 microglia dependent on its aggregation state
A Hoffmann, B Ettle, A Bruno, A Kulinich, AC Hoffmann, J von Wittgenstein, ...
Biochemical and biophysical research communications 479 (4), 881-886, 2016
612016
Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia
ACP de Oliveira, E Candelario-Jalil, J Langbein, L Wendeburg, HS Bhatia, ...
Journal of neuroinflammation 9 (1), 1-8, 2012
562012
Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile
Y Kim, X Zheng, Z Ansari, MC Bunnell, JR Herdy, L Traxler, H Lee, ...
Cell reports 23 (9), 2550-2558, 2018
532018
α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy
B Ettle, BE Kerman, E Valera, C Gillmann, JCM Schlachetzki, S Reiprich, ...
Acta neuropathologica 132 (1), 59-75, 2016
452016
Both systemic and local application of granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy
T Frank, JCM Schlachetzki, B Göricke, K Meuer, G Rohde, GPH Dietz, ...
BMC neuroscience 10 (1), 1-10, 2009
402009
Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells
B Ettle, S Reiprich, J Deusser, JCM Schlachetzki, W Xiang, I Prots, ...
Molecular and Cellular Neuroscience 62, 68-78, 2014
362014
Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE 2 in primary rat microglia
JCM Schlachetzki, BL Fiebich, E Haake, ACP de Oliveira, ...
Journal of neuroinflammation 7 (1), 1-10, 2010
362010
Automatic recognition of Parkinson's disease using surface electromyography during standardized gait tests
P Kugler, C Jaremenko, J Schlachetzki, J Winkler, J Klucken, B Eskofier
2013 35th Annual International Conference of the IEEE Engineering in …, 2013
342013
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Artigos 1–20