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Laura Esther Abelleira-Hervas
Laura Esther Abelleira-Hervas
E-mail confirmado em ic.ac.uk
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Recapitulation of human retinal development from human pluripotent stem cells generates transplantable populations of cone photoreceptors
A Gonzalez-Cordero, K Kruczek, A Naeem, M Fernando, M Kloc, J Ribeiro, ...
Stem cell reports 9 (3), 820-837, 2017
2252017
Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65
A Georgiadis, Y Duran, J Ribeiro, L Abelleira-Hervas, SJ Robbie, ...
Gene therapy 23 (12), 857-862, 2016
862016
Prevention of photoreceptor cell loss in a Cln6nclf mouse model of Batten disease requires CLN6 gene transfer to bipolar cells
SM kleine Holthaus, J Ribeiro, L Abelleira-Hervas, RA Pearson, Y Duran, ...
Molecular Therapy 26 (5), 1343-1353, 2018
472018
Cd59a deficiency in mice leads to preferential innate immune activation in the retinal pigment epithelium–choroid with age
P Herrmann, JA Cowing, E Cristante, SE Liyanage, J Ribeiro, Y Duran, ...
Neurobiology of Aging 36 (9), 2637-2648, 2015
212015
Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization
P Villacampa, KE Menger, L Abelleira, J Ribeiro, Y Duran, AJ Smith, ...
PloS one 12 (6), e0179759, 2017
182017
Stabilization of myeloid-derived HIFs promotes vascular regeneration in retinal ischemia
P Villacampa, SE Liyanage, IP Klaska, E Cristante, KE Menger, ...
Angiogenesis 23, 83-90, 2020
162020
Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision
EZ Aldunate, V Di Foggia, F Di Marco, LA Hervas, JC Ribeiro, DL Holder, ...
Scientific Reports 9 (1), 2314, 2019
92019
Intravitreal administration of recombinant human opticin protects against hyperoxia-induced pre-retinal neovascularization
IP Klaska, A White, P Villacampa, J Hoke, L Abelleira-Hervas, ...
Experimental Eye Research 215, 108908, 2022
32022
Correction: Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65
A Georgiadis, Y Duran, J Ribeiro, L Abelleira-Hervas, SJ Robbie, ...
Gene Therapy 25 (6), 450, 2018
22018
Nanomechanics of Neurotoxic Proteins: Insights at the Start of the Neurodegeneration Cascade
R Hervás, C Fernández-Ramírez, LE Abelleira, DV Laurents, ...
Bio-nanoimaging, 57-68, 2014
12014
Efficacy assessment and pre-clinical toxicology of AAV2/8-hCARp. hCNGB3, a CNGB3 gene therapy vector
J Telfer, A Georgiadis, Y Duran, J Ribeiro, L Abelleira, S Naylor, AJ Smith, ...
HUMAN GENE THERAPY 28 (12), A76-A77, 2017
2017
Transplantation of mouse ESC-derived photoreceptor precursors into AIPL1 (-/-) mouse model of retinal degeneration
J Ribeiro, M Kloc, D Goh, RD Sampson, L Abelleira, JD Hoke, AJ Smith, ...
HUMAN GENE THERAPY 28 (12), A81-A81, 2017
2017
Pre-clinical toxicology of AAV2/5-OPTIRPE65, an optimised RPE65 gene therapy vector
A Georgiadis13
HUMAN GENE THERAPY 28 (12), A77-A77, 2017
2017
AAV-mediated transduction of bipolar cells is essential to prolong photoreceptor survival in Cln6nclf mice
SK Holthaus, J Ribeiro, LA Hervas, RA Pearson, Y Duran, RD Sampson, ...
Annual Conference of the British-Society-for-Gene-and-Cell-Therapy/Joint UK …, 2017
2017
Human opticin reduces pathological preretinal neovascularization in the mouse model of oxygen-induced retinopathy.
IP Klaska, C Orr, A White, PV Alcubierre, LA Hervás, J Hoke, CV Bunce, ...
Investigative Ophthalmology & Visual Science 58 (8), 4063-4063, 2017
2017
Retinal degeneration in Cln6nclf mice, a model for vision loss in transmembrane neuronal ceroid lipofuscinoses (NCL), amenable to AAV mediated gene therapy targeting the inner …
SMK Holthaus, UF Luhmann, SA Azam, LA Hervas, Y Duran, RA Pearson, ...
HUMAN GENE THERAPY 26 (10), A8-A9, 2015
2015
Estudio neuroquímico y comportamental del efecto de la separación materna en la respuesta a un estrés agudo en la adolescencia, en ratas Wistar de ambos sexos
LEA Hervás
2012
King’s Research Portal
A Gonzalez-Cordero, K Kruczek, A Naeem, M Fernando, M Kloc, J Ribeiro, ...
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