| T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides M Harkiolaki, SL Holmes, P Svendsen, JW Gregersen, LT Jensen, ... Immunity 30 (3), 348-357, 2009 | 239 | 2009 |
| Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis MA Friese, KB Jakobsen, L Friis, R Etzensperger, MJ Craner, ... Nature medicine 14 (11), 1227-1235, 2008 | 235 | 2008 |
| P-glycoprotein inhibition: the past, the present and the future R AJ Darby, R Callaghan, R M McMahon Current drug metabolism 12 (8), 722-731, 2011 | 113 | 2011 |
| Disarming Burkholderia pseudomallei: Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo PM Ireland, RM McMahon, LE Marshall, M Halili, E Furlong, S Tay, ... Antioxidants & redox signaling 20 (4), 606-617, 2014 | 53 | 2014 |
| Four structural subclasses of the antivirulence drug target disulfide oxidoreductase DsbA provide a platform for design of subclass-specific inhibitors RM McMahon, L Premkumar, JL Martin Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (8), 1391-1401, 2014 | 50 | 2014 |
| Structure of HLA-A* 0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis RM McMahon, L Friis, C Siebold, MA Friese, L Fugger, EY Jones Acta Crystallographica Section D: Biological Crystallography 67 (5), 447-454, 2011 | 46 | 2011 |
| The central cavity of ABCB 1 undergoes alternating access during ATP hydrolysis JH van Wonderen, RM McMahon, ML O'Mara, CA McDevitt, AJ Thomson, ... The FEBS journal 281 (9), 2190-2201, 2014 | 45 | 2014 |
| The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment A Rothnie, J Storm, R McMahon, A Taylor, ID Kerr, R Callaghan FEBS letters 579 (18), 3984-3990, 2005 | 42 | 2005 |
| Dissection of the multiple sclerosis associated DR2 haplotype R Etzensperger, RM McMahon, EY Jones, L Fugger Journal of autoimmunity 31 (3), 201-207, 2008 | 33 | 2008 |
| An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1gene SV Ramagopalan, R McMahon, DA Dyment, AD Sadovnick, GC Ebers, ... BMC medical genetics 10, 1-12, 2009 | 26 | 2009 |
| Virtual screening of peptide and peptidomimetic fragments targeted to inhibit bacterial dithiol oxidase DsbA W Duprez, P Bachu, MJ Stoermer, S Tay, RM McMahon, DP Fairlie, ... PLoS One 10 (7), e0133805, 2015 | 20 | 2015 |
| Life inside and out: making and breaking protein disulfide bonds in Chlamydia S Christensen, RM McMahon, JL Martin, WM Huston Critical reviews in microbiology 45 (1), 33-50, 2019 | 19 | 2019 |
| Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1 B Mohanty, K Rimmer, RM McMahon, SJ Headey, M Vazirani, ... PLoS One 12 (3), e0173436, 2017 | 19 | 2017 |
| Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity MC Gor, B Vezina, RM McMahon, GJ King, S Panjikar, BHA Rehm, ... Scientific reports 10 (1), 17398, 2020 | 14 | 2020 |
| Virulence of the melioidosis pathogen Burkholderia pseudomallei requires the oxidoreductase membrane protein DsbB RM McMahon, PM Ireland, DS Sarovich, G Petit, CH Jenkins, ... Infection and immunity 86 (5), 10.1128/iai. 00938-17, 2018 | 14 | 2018 |
| Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase S Christensen, MK Grøftehauge, K Byriel, WM Huston, E Furlong, B Heras, ... PLoS One 11 (12), e0168485, 2016 | 13 | 2016 |
| Interrogating fragments using a protein thermal shift assay RM McMahon, MJ Scanlon, JL Martin Australian Journal of Chemistry 66 (12), 1502-1506, 2013 | 12 | 2013 |
| NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei S Nebl, WS Alwan, ML Williams, G Sharma, A Taylor, BC Doak, KL Wilde, ... Journal of Biomolecular NMR 74, 595-611, 2020 | 9 | 2020 |
| Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and … S Christensen, MA Halili, N Strange, GA Petit, WM Huston, JL Martin, ... PLoS One 14 (9), e0222595, 2019 | 7 | 2019 |
| Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility RM McMahon, M Coinçon, S Tay, B Heras, CJ Morton, MJ Scanlon, ... Acta Crystallographica Section D: Biological Crystallography 71 (12), 2386-2395, 2015 | 6 | 2015 |
