| Discovery of a new isoxazole-3-hydroxamate-based histone deacetylase 6 inhibitor SS-208 with antitumor activity in syngeneic melanoma mouse models S Shen, M Hadley, K Ustinova, J Pavlicek, T Knox, S Noonepalle, ... Journal of medicinal chemistry 62 (18), 8557-8577, 2019 | 64 | 2019 |
| Brain penetrable histone deacetylase 6 inhibitor SW-100 ameliorates memory and learning impairments in a mouse model of fragile X syndrome AP Kozikowski, S Shen, M Pardo, MT Tavares, D Szarics, V Benoy, ... ACS chemical neuroscience 10 (3), 1679-1695, 2018 | 54 | 2018 |
| RPF101, a new capsaicin-like analogue, disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast … PL de-Sá-Júnior, KFM Pasqualoto, AK Ferreira, MT Tavares, ... Toxicology and applied pharmacology 266 (3), 385-398, 2013 | 51 | 2013 |
| Dillapiole as antileishmanial agent: discovery, cytotoxic activity and preliminary SAR studies of dillapiole analogues R Parise‐Filho, KFM Pasqualoto, FMM Magri, AK Ferreira, BAVG da Silva, ... Archiv der Pharmazie 345 (12), 934-944, 2012 | 46 | 2012 |
| Cytotoxic effects of dillapiole on MDA-MB-231 cells involve the induction of apoptosis through the mitochondrial pathway by inducing an oxidative stress while altering the … AK Ferreira, PL de-Sá-Júnior, KFM Pasqualoto, RA de Azevedo, ... Biochimie 99, 195-207, 2014 | 42 | 2014 |
| Synthesis and pharmacological evaluation of selective histone deacetylase 6 inhibitors in melanoma models MT Tavares, S Shen, T Knox, M Hadley, Z Kutil, C Bařinka, A Villagra, ... ACS medicinal chemistry letters 8 (10), 1031-1036, 2017 | 38 | 2017 |
| Evaluation of protein kinase inhibitors with PLK4 cross-over potential in a pre-clinical model of cancer A Suri, AW Bailey, MT Tavares, H Gunosewoyo, CP Dyer, ... International journal of molecular sciences 20 (9), 2112, 2019 | 37 | 2019 |
| Multi-spectroscopic and theoretical analysis on the interaction between human serum albumin and a capsaicin derivative—RPF101 OA Chaves, MT Tavares, MR Cunha, R Parise-Filho, CMR Sant’Anna, ... Biomolecules 8 (3), 78, 2018 | 36 | 2018 |
| Oleanolic acid (OA) as an antileishmanial agent: Biological evaluation and in silico mechanistic insights TS Melo, CR Gattass, DC Soares, MR Cunha, C Ferreira, MT Tavares, ... Parasitology international 65 (3), 227-237, 2016 | 36 | 2016 |
| Rational design of Suprastat: a novel selective histone deacetylase 6 inhibitor with the ability to potentiate immunotherapy in melanoma models S Noonepalle, S Shen, J Ptáček, MT Tavares, G Zhang, J Stránský, ... Journal of medicinal chemistry 63 (18), 10246-10262, 2020 | 35 | 2020 |
| Mercaptoacetamide: A promising zinc-binding group for the discovery of selective histone deacetylase 6 inhibitors MT Tavares, AP Kozikowski, S Shen European Journal of Medicinal Chemistry 209, 112887, 2021 | 31 | 2021 |
| Environmentally safe condition for the synthesis of aryl and alkyl sulfonyl hydrazones via one-pot reaction MR Cunha, MT Tavares, CF Carvalho, NAT Silva, ADF Souza, ... ACS Sustainable Chemistry & Engineering 4 (4), 1899-1905, 2016 | 30 | 2016 |
| Synthesis, Molecular Modeling, and Evaluation of Novel Sulfonylhydrazones as Acetylcholinesterase Inhibitors for Alzheimer's Disease TB Fernandes, MR Cunha, RP Sakata, TM Candido, AR Baby, ... Archiv der Pharmazie 350 (11), 1700163, 2017 | 25 | 2017 |
| Novel Capsaicin Analogues as Potential Anticancer Agents: Synthesis, Biological Evaluation, and In Silico Approach MC Damião, KFM Pasqualoto, AK Ferreira, SF Teixeira, RA Azevedo, ... Archiv der Pharmazie 347 (12), 885-895, 2014 | 25 | 2014 |
| Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling GJV Pereira, MT Tavares, RA Azevedo, BB Martins, MR Cunha, ... Bioorganic & medicinal chemistry 27 (13), 2893-2904, 2019 | 23 | 2019 |
| RPF151, a novel capsaicin-like analogue: in vitro studies and in vivo preclinical antitumor evaluation in a breast cancer model AK Ferreira, MT Tavares, KFM Pasqualoto, RA de Azevedo, SF Teixeira, ... Tumor Biology 36, 7251-7267, 2015 | 23 | 2015 |
| Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot–Marie–Tooth Type 2A Mouse Model S Shen, C Picci, K Ustinova, V Benoy, Z Kutil, G Zhang, MT Tavares, ... Journal of Medicinal Chemistry 64 (8), 4810-4840, 2021 | 18 | 2021 |
| Using an in silico approach to teach 3D pharmacodynamics of the drug–target interaction process focusing on selective COX2 inhibition by Celecoxib MT Tavares, MC Primi, NATF Silva, CF Carvalho, MR Cunha, ... Journal of Chemical Education 94 (3), 380-387, 2017 | 14 | 2017 |
| Antiophidic activity of the secondary metabolite lupeol isolated from Zanthoxylum monogynum BM Dos Santos, GM Ferreira, MT Tavares, JC De Bona, MH Hirata, ... Toxicon 193, 38-47, 2021 | 12 | 2021 |
| Crystal structure of GenD2, an NAD-dependent oxidoreductase involved in the biosynthesis of gentamicin NC de Araújo, PS Bury, MT Tavares, F Huang, R Parise-Filho, P Leadlay, ... ACS chemical biology 14 (5), 925-933, 2019 | 11 | 2019 |
Roberto Parise FilhoProfessor of Medicinal Chemistry, University of Sao PauloE-mail confirmado em usp.br
