Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds F Oesch Xenobiotica 3 (5), 305-340, 1973 | 1066 | 1973 |
A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide F Oesch, DM Jerina, J Daly Biochimica et Biophysica Acta (BBA)-Enzymology 227 (3), 685-691, 1971 | 541 | 1971 |
Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations—many questions, some answers R Landsiedel, MD Kapp, M Schulz, K Wiench, F Oesch Mutation Research/Reviews in Mutation Research 681 (2-3), 241-258, 2009 | 465 | 2009 |
A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathioneS-transferase GSTM1 and GSTT1 polymorphisms M Arand, R Mühlbauer, J Hengstler, E Jäger, J Fuchs, L Winkler, F Oesch Analytical biochemistry 236 (1), 184-186, 1996 | 449 | 1996 |
Immunoselection in vivo: independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma E Jäger, M Ringhoffer, M Altmannsberger, M Arand, J Karbach, D Jäger, ... International journal of cancer 71 (2), 142-147, 1997 | 409 | 1997 |
Hepatic epoxide hydrase. Structure-activity relations for substrates and inhibitors F Oesch, N Kaubisch, DM Jerina, JW Daly Biochemistry 10 (26), 4858-4866, 1971 | 394 | 1971 |
Granulocyte‐macrophage‐colony‐stimulating factor enhances immune responses to melanoma‐associated peptides in vivo E Jäger, M Ringhoffer, HP Dienes, M Arand, J Karbach, D Jäger, ... International journal of cancer 67 (1), 54-62, 1996 | 376 | 1996 |
Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron T Efferth, A Benakis, MR Romero, M Tomicic, R Rauh, D Steinbach, ... Free Radical Biology and Medicine 37 (7), 998-1009, 2004 | 372 | 2004 |
Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic‐T‐cell responses: Evidence for immunoselection of antigen … E Jäger, M Ringhoffer, J Karbach, M Arand, F Oesch, A Knuth International Journal of Cancer 66 (4), 470-476, 1996 | 352 | 1996 |
Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction JANG HENGSTLER, D Utesch, P Steinberg, KL Platt, B Diener, M Ringel, ... Drug metabolism reviews 32 (1), 81-118, 2000 | 345 | 2000 |
Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected JG Hengstler, U Bolm-Audorff, A Faldum, K Janssen, M Reifenrath, ... Carcinogenesis 24 (1), 63-73, 2003 | 341 | 2003 |
New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures R Gebhardt, JG Hengstler, D Müller, R Glöckner, P Buenning, B Laube, ... Drug metabolism reviews 35 (2-3), 145-213, 2003 | 329 | 2003 |
Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 325 | 2017 |
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility JG Hengstler, M Arand, ME Herrero, F Oesch Genes and environment in cancer, 47-85, 1998 | 307 | 1998 |
Of mice and models: improved animal models for biomedical research E Bockamp, M Maringer, C Spangenberg, S Fees, S Fraser, L Eshkind, ... Physiological genomics 11 (3), 115-132, 2002 | 258 | 2002 |
Structure of Aspergillus niger epoxide hydrolase at 1.8 Å resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases J Zou, BM Hallberg, T Bergfors, F Oesch, M Arand, SL Mowbray, TA Jones Structure 8 (2), 111-122, 2000 | 238 | 2000 |
Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways B Oesch-Bartlomowicz, A Huelster, O Wiss, P Antoniou-Lipfert, C Dietrich, ... Proceedings of the National Academy of Sciences 102 (26), 9218-9223, 2005 | 227 | 2005 |
Drug-metabolizing enzymes in the skin of man, rat, and pig F Oesch, E Fabian, B Oesch-Bartlomowicz, C Werner, R Landsiedel Drug metabolism reviews 39 (4), 659-698, 2007 | 225 | 2007 |
Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins: implication for the potential catalytic mechanism of … M Arand, DF Grant, JK Beetham, T Friedberg, F Oesch, BD Hammock FEBS letters 338 (3), 251-256, 1994 | 223 | 1994 |
Toxico-/biokinetics of nanomaterials R Landsiedel, E Fabian, L Ma-Hock, W Wohlleben, K Wiench, F Oesch, ... Archives of toxicology 86, 1021-1060, 2012 | 212 | 2012 |