Recent Advances in the Synthesis of Spiro‐β‐Lactams and Spiro‐δ‐Lactams NA Guerreiro Alves, AJ dos Santos Alves, MI Lopes Soares, ... Advanced Synthesis & Catalysis, 2021 | 29 | 2021 |
Strategies and methodologies for the construction of spiro-γ-lactams: an update AJS Alves, NG Alves, MIL Soares, TMVDP e Melo Organic Chemistry Frontiers 8 (13), 3543-3593, 2021 | 24 | 2021 |
Synthesis and structure-activity relationships of new chiral spiro-β-lactams highly active against HIV-1 and Plasmodium NG Alves, I Bártolo, AJS Alves, D Fontinha, D Francisco, SMM Lopes, ... European Journal of Medicinal Chemistry 219, 113439, 2021 | 21 | 2021 |
Spiro-lactams as novel antimicrobial agents AJS Alves, NG Alves, CC Caratão, MIM Esteves, D Fontinha, I Bártolo, ... Current Topics in Medicinal Chemistry 20 (2), 140-152, 2020 | 21 | 2020 |
Hetero‐Diels–Alder and Ring‐Opening Reactions of Furans Applied to the Synthesis of Functionalized Heterocycles AJS Alves, SMM Lopes, MSC Henriques, JA Paixão, TMVD Pinho e Melo European Journal of Organic Chemistry 2017 (27), 4011-4025, 2017 | 21 | 2017 |
Spiro-β-lactam BSS-730A displays potent activity against HIV and Plasmodium I Bártolo, BS Santos, D Fontinha, M Machado, D Francisco, B Sepodes, ... ACS Infectious Diseases 7 (2), 421-434, 2021 | 15 | 2021 |
Synthesis of novel chiral spiroisoxazolidine‐β‐lactams from 6‐alkylidenepenicillanates: A 1, 3‐dipolar cycloaddition approach AJS Alves, TMVD Pinho e Melo European Journal of Organic Chemistry 2020 (39), 6259-6269, 2020 | 9 | 2020 |
Insights into the anticancer activity of chiral alkylidene-β-lactams and alkylidene-γ-lactams: Synthesis and biological investigation AJS Alves, NG Alves, M Laranjo, CSB Gomes, AC Gonçalves, ... Bioorganic & Medicinal Chemistry 63, 116738, 2022 | 4 | 2022 |
Unveiling a family of spiro-β-lactams with anti-HIV and antiplasmodial activity via phosphine-catalyzed [3+ 2] annulation of 6-alkylidene-penicillanates and allenoates AJS Alves, NG Alves, I Bártolo, D Fontinha, S Caetano, M Prudêncio, ... Frontiers in Chemistry 10, 1017250, 2022 | 3 | 2022 |
High instantaneous inhibitory potential of Bictegravir and the New Spiro-β-Lactam BSS-730A for HIV-2 isolates from RAL-naïve and RAL-failing patients I Bártolo, I Moranguinho, P Gonçalves, AR Diniz, P Borrego, F Martin, ... International Journal of Molecular Sciences 23 (22), 14300, 2022 | 2 | 2022 |
Synthesis of novel chiral spiro-β-lactams from nitrile oxides and 6-(Z)-(benzoylmethylene) penicillanate: batch, microwave-induced and continuous flow methodologies AJS Alves, JAD Silvestre, TMVDP e Melo RSC advances 12 (48), 30879-30891, 2022 | 2 | 2022 |
Furanos na síntese de novos compostos heterocíclicos AJS Alves | 1 | 2016 |
Novel spiro-lactams as new antimicrobial agents AJS Alves Novel spiro-lactams as new antimicrobial agents, 2023 | | 2023 |