Jonathon Winnay

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Marcelo A. MoriDepartment of Biochemistry and Tissue Biology - Institute of Biology - State University of CampinasE-mail confirmado em unicamp.br
Yu-Hua TsengJoslin Diabetes Center, Harvard Medical SchoolE-mail confirmado em joslin.harvard.edu
Jeremie BoucherAstraZeneca R&D Gothenburg, SwedenE-mail confirmado em astrazeneca.com
Mark A MagnusonVanderbilt UniversityE-mail confirmado em vanderbilt.edu
Jonathan M DreyfussJoslin Diabetes CenterE-mail confirmado em joslin.harvard.edu
Simeon I. TaylorProfessor of Medicine, University of Maryland School of MedicineE-mail confirmado em medicine.umaryland.edu
Lewis CantleyWeill Cornell Medical CollegeE-mail confirmado em med.cornell.edu
Ulupi JhalaUCSDE-mail confirmado em ucsd.edu
Weikang CaiNew York Institute of Technology, College of Osteopathic MedicineE-mail confirmado em nyit.edu
Kristy TownsendThe Ohio State UniversityE-mail confirmado em osumc.edu
gerard karsentyProfessor of Genetics and Development, Columbia University Medical CenterE-mail confirmado em columbia.edu
Morris F WhiteProfessor of Pediatrics, Harvard Medical SchoolE-mail confirmado em childrens.harvard.edu
Sarah E. RossUniversity of PittsburghE-mail confirmado em pitt.edu
Ormond MacDougaldJohn A Faulkner Collegiate Professor of Physiology. University of Michigan Medical CenterE-mail confirmado em umich.edu
Ercument DiriceResearch Associate at Joslin Diabetes Center - Instructor at Harvard Medical SchoolE-mail confirmado em joslin.harvard.edu
Franck Mauvais-JarvisDirector, Diabetes Discovery Research Laboratory - Price-Goldsmith Professor, Tulane UniversityE-mail confirmado em tulane.edu
Bert W. O'MalleyBaylor College of MedicineE-mail confirmado em bcm.edu
Mengyao Ella LiHarvard Medical SchoolE-mail confirmado em joslin.harvard.edu
Kevin LeeOhio UniversityE-mail confirmado em ohio.edu
Franco FolliUniversity of Milano, Department of Health Science; Endocrinology and Metabolism - ASST Santi PaoloE-mail confirmado em unimi.it

Jonathon Winnay

Joslin Diabetes Center, Harvard Medical School

E-mail confirmado em joslin.harvard.edu

Insulin Resistance Type 2 diabetes


Título Ordenar por citações Ordenar por ano Ordenar por título	Citado por Citado por	Ano
Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes RN Kulkarni, JC Brüning, JN Winnay, C Postic, MA Magnuson, CR Kahn Cell 96 (3), 329-339, 1999	1340	1999
A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance JC Brüning, MD Michael, JN Winnay, T Hayashi, D Hörsch, D Accili, ... Molecular cell 2 (5), 559-569, 1998	1258	1998
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure YH Tseng, E Kokkotou, TJ Schulz, TL Huang, JN Winnay, CM Taniguchi, ... Nature 454 (7207), 1000-1004, 2008	1087	2008
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure YH Tseng, E Kokkotou, TJ Schulz, TL Huang, JN Winnay, CM Taniguchi, ... Nature 454 (7207), 1000-1004, 2008	1087	2008
Adipose-derived circulating miRNAs regulate gene expression in other tissues T Thomou, MA Mori, JM Dreyfuss, M Konishi, M Sakaguchi, C Wolfrum, ... Nature 542 (7642), 450-455, 2017	691	2017
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles JC Brüning, J Winnay, S Bonner-Weir, SI Taylor, D Accili, CR Kahn Cell 88 (4), 561-572, 1997	654	1997
Altered function of insulin receptor substrate-1–deficient mouse islets and cultured β-cell lines RN Kulkarni, JN Winnay, M Daniels, JC Brüning, SN Flier, D Hanahan, ... The Journal of clinical investigation 104 (12), R69-R75, 1999	318	1999
PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance RN Kulkarni, US Jhala, JN Winnay, S Krajewski, M Montminy, CR Kahn The Journal of clinical investigation 114 (6), 828-836, 2004	286	2004
Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells. JC Brüning, J Winnay, B Cheatham, CR Kahn Molecular and cellular biology 17 (3), 1513-1521, 1997	276	1997
A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box–binding protein-1 to modulate the unfolded protein response JN Winnay, J Boucher, MA Mori, K Ueki, CR Kahn Nature medicine 16 (4), 438-445, 2010	185	2010
Phosphorylation of C/EBPα inhibits granulopoiesis SE Ross, HS Radomska, B Wu, P Zhang, JN Winnay, L Bajnok, ... Molecular and cellular biology 24 (2), 675-686, 2004	178	2004
Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2 A Assmann, K Ueki, JN Winnay, T Kadowaki, RN Kulkarni Molecular and cellular biology 29 (11), 3219-3228, 2009	151	2009
Specific roles of the p110α isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation VR Sopasakis, P Liu, R Suzuki, T Kondo, J Winnay, TT Tran, T Asano, ... Cell metabolism 11 (3), 220-230, 2010	140	2010
Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice RN Kulkarni, K Almind, HJ Goren, JN Winnay, K Ueki, T Okada, CR Kahn Diabetes 52 (6), 1528-1534, 2003	132	2003
The phosphoinositide 3-kinase regulatory subunit p85α can exert tumor suppressor properties through negative regulation of growth factor signaling CM Taniguchi, J Winnay, T Kondo, RT Bronson, AR Guimaraes, ... Cancer research 70 (13), 5305-5315, 2010	126	2010
Convergence of Wnt signaling and steroidogenic factor-1 (SF-1) on transcription of the rat inhibin α gene BM Gummow, JN Winnay, GD Hammer Journal of Biological Chemistry 278 (29), 26572-26579, 2003	107	2003
Micro RNA‐455 regulates brown adipogenesis via a novel HIF 1an‐AMPK‐PGC 1α signaling network H Zhang, M Guan, KL Townsend, TL Huang, D An, X Yan, R Xue, ... EMBO reports 16 (10), 1378-1393, 2015	104	2015
A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes. F Mauvais-Jarvis, A Virkamaki, MD Michael, JN Winnay, A Zisman, ... Diabetes 49 (12), 2126-2134, 2000	102	2000
SHORT syndrome with partial lipodystrophy due to impaired phosphatidylinositol 3 kinase signaling KK Chudasama, J Winnay, S Johansson, T Claudi, R König, I Haldorsen, ... The American Journal of Human Genetics 93 (1), 150-157, 2013	95	2013
Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5) J Palsgaard, B Emanuelli, JN Winnay, G Sumara, G Karsenty, CR Kahn Journal of Biological Chemistry 287 (15), 12016-12026, 2012	87	2012

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