| Branched-chain amino acids in metabolic signalling and insulin resistance CJ Lynch, SH Adams Nature Reviews Endocrinology 10 (12), 723-736, 2014 | 1262 | 2014 |
| Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism P She, C Van Horn, T Reid, SM Hutson, RN Cooney, CJ Lynch American Journal of Physiology-Endocrinology and Metabolism 293 (6), E1552-E1563, 2007 | 532 | 2007 |
| Catabolic defect of branched-chain amino acids promotes heart failure H Sun, KC Olson, C Gao, DA Prosdocimo, M Zhou, Z Wang, D Jeyaraj, ... Circulation 133 (21), 2038-2049, 2016 | 439 | 2016 |
| Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels MA Herman, P She, OD Peroni, CJ Lynch, BB Kahn Journal of Biological Chemistry 285 (15), 11348-11356, 2010 | 403 | 2010 |
| Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle P She, TM Reid, SK Bronson, TC Vary, A Hajnal, CJ Lynch, SM Hutson Cell metabolism 6 (3), 181-194, 2007 | 391 | 2007 |
| Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity DE Lackey, CJ Lynch, KC Olson, R Mostaedi, M Ali, WH Smith, F Karpe, ... American Journal of Physiology-Endocrinology and Metabolism 304 (11), E1175 …, 2013 | 327 | 2013 |
| Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity J Li, C Romestaing, X Han, Y Li, X Hao, Y Wu, C Sun, X Liu, LS Jefferson, ... Cell metabolism 12 (2), 154-165, 2010 | 293 | 2010 |
| Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate. CJ Lynch, R Charest, SB Bocckino, JH Exton, PF Blackmore Journal of Biological Chemistry 260 (5), 2844-2851, 1985 | 262 | 1985 |
| Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue CJ Lynch, BJ Patson, J Anthony, A Vaval, LS Jefferson, TC Vary American Journal of Physiology-Endocrinology and Metabolism 283 (3), E503-E513, 2002 | 224 | 2002 |
| Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents VL Albaugh, CR Henry, NT Bello, A Hajnal, SL Lynch, B Halle, CJ Lynch Obesity 14 (1), 36-51, 2006 | 214 | 2006 |
| Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells G Lu, H Sun, P She, JY Youn, S Warburton, P Ping, TM Vondriska, H Cai, ... The Journal of clinical investigation 119 (6), 1678-1687, 2009 | 212 | 2009 |
| Role of leucine in the regulation of mTOR by amino acids: revelations from structure–activity studies CJ Lynch The Journal of nutrition 131 (3), 861S-865S, 2001 | 210 | 2001 |
| Regulation of amino acid–sensitive TOR signaling by leucine analogues in adipocytes CJ Lynch, HL Fox, TC Vary, LS Jefferson, SR Kimball Journal of cellular biochemistry 77 (2), 234-251, 2000 | 194 | 2000 |
| Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice NM Agostino, VM Chinchilli, CJ Lynch, A Koszyk-Szewczyk, R Gingrich, ... Journal of Oncology Pharmacy Practice 17 (3), 197-202, 2011 | 181 | 2011 |
| Leucine in food mediates some of the postprandial rise in plasma leptin concentrations CJ Lynch, B Gern, C Lloyd, SM Hutson, R Eicher, TC Vary American Journal of Physiology-Endocrinology and Metabolism 291 (3), E621-E630, 2006 | 172 | 2006 |
| Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats CJ Lynch, SM Hutson, BJ Patson, A Vaval, TC Vary American Journal of Physiology-Endocrinology and Metabolism 283 (4), E824-E835, 2002 | 172 | 2002 |
| Amino acids stimulate phosphorylation of p70 S6k and organization of rat adipocytes into multicellular clusters HL Fox, SR Kimball, LS Jefferson, CJ Lynch American Journal of Physiology-Cell Physiology 274 (1), C206-C213, 1998 | 162 | 1998 |
| Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism AC Shin, M Fasshauer, N Filatova, LA Grundell, E Zielinski, JY Zhou, ... Cell metabolism 20 (5), 898-909, 2014 | 154 | 2014 |
| Gastric bypass surgery alters behavioral and neural taste functions for sweet taste in obese rats A Hajnal, P Kovacs, T Ahmed, K Meirelles, CJ Lynch, RN Cooney American Journal of Physiology-Gastrointestinal and Liver Physiology 299 (4 …, 2010 | 151 | 2010 |
| Amino acid effects on translational repressor 4E-BP1 are mediated primarily by L-leucine in isolated adipocytes HL Fox, PT Pham, SR Kimball, LS Jefferson, CJ Lynch American Journal of Physiology-Cell Physiology 275 (5), C1232-C1238, 1998 | 151 | 1998 |
