Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β LA Paige, DJ Christensen, H Grøn, JD Norris, EB Gottlin, KM Padilla, ... Proceedings of the National Academy of Sciences 96 (7), 3999-4004, 1999 | 537 | 1999 |
Peptide antagonists of the human estrogen receptor JD Norris, LA Paige, DJ Christensen, CY Chang, MR Huacani, D Fan, ... Science 285 (5428), 744-746, 1999 | 481 | 1999 |
Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors α and β C Chang, JD Norris, H Grøn, LA Paige, PT Hamilton, DJ Kenan, ... Molecular and cellular biology, 1999 | 465 | 1999 |
Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest A Puga, SJ Barnes, TP Dalton, C Chang, ES Knudsen, MA Maier Journal of Biological Chemistry 275 (4), 2943-2950, 2000 | 413 | 2000 |
Constitutive activation of the aromatic hydrocarbon receptor CY Chang, A Puga Molecular and cellular biology 18 (1), 525-535, 1998 | 312 | 1998 |
The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells AE Baek, YRA Yu, S He, SE Wardell, CY Chang, S Kwon, RV Pillai, ... Nature communications 8 (1), 864, 2017 | 311 | 2017 |
The homeodomain protein HOXB13 regulates the cellular response to androgens JD Norris, CY Chang, BM Wittmann, RS Kunder, H Cui, D Fan, JD Joseph, ... Molecular cell 36 (3), 405-416, 2009 | 255 | 2009 |
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation RD Michalek, VA Gerriets, AG Nichols, M Inoue, D Kazmin, CY Chang, ... Proceedings of the National Academy of Sciences 108 (45), 18348-18353, 2011 | 234 | 2011 |
Cholesterol and breast cancer pathophysiology ER Nelson, C Chang, DP McDonnell Trends in Endocrinology & Metabolism 25 (12), 649-655, 2014 | 212 | 2014 |
Estrogen-related receptor α is critical for the growth of estrogen receptor–negative breast cancer RA Stein, C Chang, DA Kazmin, J Way, T Schroeder, M Wergin, ... Cancer research 68 (21), 8805-8812, 2008 | 184 | 2008 |
Dioxin induces transcription of fos and jun genes by Ah receptor-dependent and-independent pathways A Hoffer, C Chang, A Puga Toxicology and applied pharmacology 141 (1), 238-247, 1996 | 178 | 1996 |
The metabolic regulator ERRα, a downstream target of HER2/IGF-1R, as a therapeutic target in breast cancer C Chang, D Kazmin, JS Jasper, R Kunder, WJ Zuercher, DP McDonnell Cancer cell 20 (4), 500-510, 2011 | 164 | 2011 |
WNT11 expression is induced by estrogen-related receptor α and β-catenin and acts in an autocrine manner to increase cancer cell migration MA Dwyer, JD Joseph, HE Wade, ML Eaton, RS Kunder, D Kazmin, ... Cancer research 70 (22), 9298-9308, 2010 | 163 | 2010 |
Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators DP McDonnell, CE Connor, A Wijayaratne, CY Chang, JD Norris Recent progress in hormone research 57, 295-316, 2002 | 152 | 2002 |
Activation of transcription factors activator protein-1 and nuclear factor-κB by 2,3,7,8-Tetrachlorodibenzo-p-dioxin A Puga, SJ Barnes, C Chang, H Zhu, KP Nephew, SA Khan, HG Shertzer Biochemical pharmacology 59 (8), 997-1005, 2000 | 143 | 2000 |
Ligand-specific dynamics of the androgen receptor at its response element in living cells TI Klokk, P Kurys, C Elbi, AK Nagaich, A Hendarwanto, T Slagsvold, ... Molecular and cellular biology 27 (5), 1823-1843, 2007 | 141 | 2007 |
Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer W Liu, B Chakraborty, R Safi, D Kazmin, C Chang, DP McDonnell Nature communications 12 (1), 5103, 2021 | 139 | 2021 |
ERRα-regulated lactate metabolism contributes to resistance to targeted therapies in breast cancer S Park, CY Chang, R Safi, X Liu, R Baldi, JS Jasper, GR Anderson, T Liu, ... Cell reports 15 (2), 323-335, 2016 | 135 | 2016 |
Ten nucleotide differences, five of which cause amino acid changes, are associated with the Ah receptor locus polymorphism of C57BL/6 and DBA/2 mice C Chang, DR Smith, VS Prasad, CL Sidman, DW Nebert, A Puga Pharmacogenetics and Genomics 3 (6), 312-321, 1993 | 128 | 1993 |
Obesity, cholesterol metabolism, and breast cancer pathogenesis DP McDonnell, S Park, MT Goulet, J Jasper, SE Wardell, C Chang, ... Cancer research 74 (18), 4976-4982, 2014 | 124 | 2014 |