Daniel Bolon
Daniel Bolon
E-mail confirmado em umassmed.edu
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Enzyme-like proteins by computational design
DN Bolon, SL Mayo
Proceedings of the National Academy of Sciences 98 (25), 14274-14279, 2001
4862001
Sculpting the proteome with AAA+ proteases and disassembly machines
RT Sauer, DN Bolon, BM Burton, RE Burton, JM Flynn, RA Grant, ...
Cell 119 (1), 9-18, 2004
4582004
Experimental illumination of a fitness landscape
RT Hietpas, JD Jensen, DNA Bolon
Proceedings of the National Academy of Sciences 108 (19), 7896-7901, 2011
2572011
De novo design of biocatalysts
DN Bolon, CA Voigt, SL Mayo
Current opinion in chemical biology 6 (2), 125-129, 2002
1902002
Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: allosteric control of a protein machine
GL Hersch, RE Burton, DN Bolon, TA Baker, RT Sauer
Cell 121 (7), 1017-1027, 2005
1722005
Analyses of the effects of all ubiquitin point mutants on yeast growth rate
BP Roscoe, KM Thayer, KB Zeldovich, D Fushman, DNA Bolon
Journal of molecular biology 425 (8), 1363-1377, 2013
1712013
Specificity versus stability in computational protein design
DN Bolon, RA Grant, TA Baker, RT Sauer
Proceedings of the National Academy of Sciences 102 (36), 12724-12729, 2005
1492005
Dimerization of Hsp90 is required for in Vivo Function design and analysis of monomers and dimers
N Wayne, DN Bolon
Journal of Biological Chemistry 282 (48), 35386-35395, 2007
1042007
Flexible linkers leash the substrate binding domain of SspB to a peptide module that stabilizes delivery complexes with the AAA+ ClpXP protease
DA Wah, I Levchenko, GE Rieckhof, DN Bolon, TA Baker, RT Sauer
Molecular cell 12 (2), 355-363, 2003
1012003
Influenza virus drug resistance: a time-sampled population genetics perspective
M Foll, YP Poh, N Renzette, A Ferrer-Admetlla, C Bank, H Shim, ...
PLoS Genet 10 (2), e1004185, 2014
962014
Shifting fitness landscapes in response to altered environments
RT Hietpas, C Bank, JD Jensen, DNA Bolon
Evolution 67 (12), 3512-3522, 2013
962013
A systematic survey of an intragenic epistatic landscape
C Bank, RT Hietpas, JD Jensen, DNA Bolon
Molecular biology and evolution 32 (1), 229-238, 2015
922015
Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease
DN Bolon, RA Grant, TA Baker, RT Sauer
Molecular cell 16 (3), 343-350, 2004
842004
A Bayesian MCMC approach to assess the complete distribution of fitness effects of new mutations: uncovering the potential for adaptive walks in challenging environments
C Bank, RT Hietpas, A Wong, DN Bolon, JD Jensen
Genetics 196 (3), 841-852, 2014
802014
Latent effects of Hsp90 mutants revealed at reduced expression levels
L Jiang, P Mishra, RT Hietpas, KB Zeldovich, DNA Bolon
PLoS Genet 9 (6), e1003600, 2013
682013
Bivalent tethering of SspB to ClpXP is required for efficient substrate delivery: a protein-design study
DN Bolon, DA Wah, GL Hersch, TA Baker, RT Sauer
Molecular cell 13 (3), 443-449, 2004
652004
Fitness analyses of all possible point mutations for regions of genes in yeast
R Hietpas, B Roscoe, L Jiang, DNA Bolon
Nature protocols 7 (7), 1382-1396, 2012
642012
Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease
S Mittal, Y Cai, MNL Nalam, DNA Bolon, CA Schiffer
Journal of the American Chemical Society 134 (9), 4163-4168, 2012
612012
Hsp90 and client protein maturation
N Wayne, P Mishra, DN Bolon
Molecular Chaperones, 33-44, 2011
592011
Systematic mutant analyses elucidate general and client-specific aspects of Hsp90 function
P Mishra, JM Flynn, TN Starr, DNA Bolon
Cell reports 15 (3), 588-598, 2016
572016
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