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Maxwell Mumbach
Maxwell Mumbach
Founding Scientist, Head of Discovery at Cartography Biosciences
E-mail confirmado em cartography.bio
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An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
MR Corces, AE Trevino, EG Hamilton, PG Greenside, ...
Nature methods 14 (10), 959-962, 2017
17912017
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5′ sites
S Schwartz, MR Mumbach, M Jovanovic, T Wang, K Maciag, GG Bushkin, ...
Cell reports 8 (1), 284-296, 2014
11322014
HiChIP: efficient and sensitive analysis of protein-directed genome architecture
MR Mumbach, AJ Rubin, RA Flynn, C Dai, PA Khavari, WJ Greenleaf, ...
Nature methods 13 (11), 919-922, 2016
9562016
The chromatin accessibility landscape of primary human cancers
MR Corces, JM Granja, S Shams, BH Louie, JA Seoane, W Zhou, ...
Science 362 (6413), eaav1898, 2018
9342018
Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA
S Schwartz, DA Bernstein, MR Mumbach, M Jovanovic, RH Herbst, ...
Cell 159 (1), 148-162, 2014
9042014
Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion
AT Satpathy, JM Granja, KE Yost, Y Qi, F Meschi, GP McDermott, ...
Nature biotechnology 37 (8), 925-936, 2019
6672019
High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis
S Schwartz, SD Agarwala, MR Mumbach, M Jovanovic, P Mertins, ...
Cell 155 (6), 1409-1421, 2013
6372013
Dynamic profiling of the protein life cycle in response to pathogens
M Jovanovic, MS Rooney, P Mertins, D Przybylski, N Chevrier, R Satija, ...
Science 347 (6226), 1259038, 2015
4902015
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements
MR Mumbach, AT Satpathy, EA Boyle, C Dai, BG Gowen, SW Cho, ...
Nature genetics 49 (11), 1602-1612, 2017
4482017
Promoter of lncRNA gene PVT1 is a tumor-suppressor DNA boundary element
SW Cho, J Xu, R Sun, MR Mumbach, AC Carter, YG Chen, KE Yost, J Kim, ...
Cell 173 (6), 1398-1412. e22, 2018
4092018
Transcriptome-Wide Mapping of 5-methylcytidine RNA Modifications in Bacteria, Archaea, and Yeast Reveals m5C within Archaeal mRNAs
S Edelheit, S Schwartz, MR Mumbach, O Wurtzel, R Sorek
PLoS genetics 9 (6), e1003602, 2013
3732013
Lineage-specific dynamic and pre-established enhancer–promoter contacts cooperate in terminal differentiation
AJ Rubin, BC Barajas, M Furlan-Magaril, V Lopez-Pajares, MR Mumbach, ...
Nature genetics 49 (10), 1522-1528, 2017
2872017
Discovery of stimulation-responsive immune enhancers with CRISPR activation
DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ...
Nature 549 (7670), 111-115, 2017
2782017
Coupled single-cell CRISPR screening and epigenomic profiling reveals causal gene regulatory networks
AJ Rubin, KR Parker, AT Satpathy, Y Qi, B Wu, AJ Ong, MR Mumbach, ...
Cell 176 (1), 361-376. e17, 2019
2402019
Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer’s and Parkinson’s diseases
MR Corces, A Shcherbina, S Kundu, MJ Gloudemans, L Frésard, ...
Nature genetics 52 (11), 1158-1168, 2020
2382020
Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE
RA Flynn, QC Zhang, RC Spitale, B Lee, MR Mumbach, HY Chang
Nature protocols 11 (2), 273-290, 2016
1562016
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
RA Flynn, JA Belk, Y Qi, Y Yasumoto, J Wei, MM Alfajaro, Q Shi, ...
Cell 184 (9), 2394-2411. e16, 2021
153*2021
Transcript-indexed ATAC-seq for precision immune profiling
AT Satpathy, N Saligrama, JD Buenrostro, Y Wei, B Wu, AJ Rubin, ...
Nature medicine 24 (5), 580-590, 2018
1232018
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
E López-Isac, M Acosta-Herrera, M Kerick, S Assassi, AT Satpathy, ...
Nature communications 10 (1), 4955, 2019
1182019
LeafJ: an ImageJ plugin for semi-automated leaf shape measurement
JN Maloof, K Nozue, MR Mumbach, CM Palmer
JoVE (Journal of Visualized Experiments), e50028, 2013
1092013
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