| Reversal of Neuromusclar Blockade and Simultaneous Increase in Plasma Rocuronium Concentration after the Intravenous Infusion of the Novel Reversal Agent Org 25970 O Epemolu, A Bom, F Hope, R Mason The Journal of the American Society of Anesthesiologists 99 (3), 632-637, 2003 | 208 | 2003 |
| Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition J Frost, C Galdeano, P Soares, MS Gadd, KM Grzes, L Ellis, O Epemolu, ... Nature communications 7 (1), 13312, 2016 | 197 | 2016 |
| Development of a novel lead that targets M. tuberculosis polyketide synthase 13 A Aggarwal, MK Parai, N Shetty, D Wallis, L Woolhiser, C Hastings, ... Cell 170 (2), 249-259. e25, 2017 | 149 | 2017 |
| Group-based optimization of potent and cell-active inhibitors of the von Hippel–Lindau (VHL) E3 ubiquitin ligase: structure–activity relationships leading to the chemical probe … P Soares, MS Gadd, J Frost, C Galdeano, L Ellis, O Epemolu, S Rocha, ... Journal of medicinal chemistry 61 (2), 599-618, 2018 | 137 | 2018 |
| The first potent and selective inhibitors of the glycine transporter type 2 WL Caulfield, IT Collie, RS Dickins, O Epemolu, R McGuire, DR Hill, ... Journal of medicinal chemistry 44 (17), 2679-2682, 2001 | 124 | 2001 |
| Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis Y Park, A Pacitto, T Bayliss, LAT Cleghorn, Z Wang, T Hartman, K Arora, ... ACS infectious diseases 3 (1), 18-33, 2017 | 85 | 2017 |
| Comparison of the platelet pro‐aggregatory effect of conventional unfractionated heparins and a low molecular weight heparin fraction (CY 222) MA Barradas, DP Mikhailidis, O Epemolu, JY Jeremy, V Fonseca, ... British journal of haematology 67 (4), 451-457, 1987 | 71 | 1987 |
| Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB LAT Cleghorn, PC Ray, J Odingo, A Kumar, H Wescott, A Korkegian, ... Journal of Medicinal Chemistry 61 (15), 6592-6608, 2018 | 56 | 2018 |
| 2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action … D Murugesan, PC Ray, T Bayliss, GA Prosser, JR Harrison, K Green, ... ACS infectious diseases 4 (6), 954-969, 2018 | 56 | 2018 |
| Liquid chromatography/mass spectrometric bioanalysis of a modified γ‐cyclodextrin (Org 25969) and Rocuronium bromide (Org 9426) in guinea pig plasma and urine: its application … O Epemolu, I Mayer, F Hope, P Scullion, P Desmond Rapid communications in mass spectrometry 16 (20), 1946-1952, 2002 | 50 | 2002 |
| Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi S Brand, EJ Ko, E Viayna, S Thompson, D Spinks, M Thomas, L Sandberg, ... Journal of medicinal chemistry 60 (17), 7284-7299, 2017 | 44 | 2017 |
| Selective relaxant binding agents for reversal of neuromuscular blockade A Bom, O Epemolu, F Hope, S Rutherford, K Thomson Current opinion in pharmacology 7 (3), 298-302, 2007 | 43 | 2007 |
| Lessons from preclinical and clinical studies with 1, 2-diethyl-3-hydroxypyridin-4-one, CP94 and related compounds JB Porter, S Singh, KP Hoyes, O Epemolu, RD Abeysinghe, RC Hider Progress in Iron Research, 361-370, 1994 | 42 | 1994 |
| Optimization of a “bump-and-hole” approach to allele-selective BET bromodomain inhibition AC Runcie, M Zengerle, KH Chan, A Testa, L Van Beurden, MGJ Baud, ... Chemical Science 9 (9), 2452-2468, 2018 | 40 | 2018 |
| Ethanol ingestion inhibits human whole blood platelet impedance aggregation DP Mikhailidis, MA Barradas, O Epemolu, P Dandona American journal of clinical pathology 88 (3), 342-345, 1987 | 39 | 1987 |
| Pharmacokinetics of β-lactam antibiotics: clues from the past to help discover long-acting oral drugs in the future PW Smith, F Zuccotto, RH Bates, MS Martinez-Martinez, KD Read, C Peet, ... ACS infectious diseases 4 (10), 1439-1447, 2018 | 36 | 2018 |
| Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors P Ray, J Wright, J Adam, J Bennett, S Boucharens, D Black, A Cook, ... Bioorganic & medicinal chemistry letters 21 (1), 97-101, 2011 | 35 | 2011 |
| Optimisation of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors P Ray, J Wright, J Adam, S Boucharens, D Black, AR Brown, O Epemolu, ... Bioorganic & medicinal chemistry letters 21 (4), 1084-1088, 2011 | 34 | 2011 |
| Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite … C McKenzie, OB Sutcliffe, KD Read, P Scullion, O Epemolu, D Fletcher, ... Forensic toxicology 36, 359-374, 2018 | 31 | 2018 |
| Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani LS Torrie, S Brand, DA Robinson, EJ Ko, L Stojanovski, FRC Simeons, ... ACS infectious diseases 3 (10), 718-727, 2017 | 28 | 2017 |
