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Andrea Cuconati
Andrea Cuconati
Arbutus Biopharma, Inc.
E-mail confirmado em arbutusbio.com
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DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
A Cuconati, C Mukherjee, D Perez, E White
Genes & development 17 (23), 2922-2932, 2003
4392003
Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection
A Cuconati, E White
Genes & development 16 (19), 2465-2478, 2002
3802002
Characterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formation
H Guo, D Jiang, T Zhou, A Cuconati, TM Block, JT Guo
Journal of virology 81 (22), 12472-12484, 2007
3562007
Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formation
D Cai, C Mills, W Yu, R Yan, CE Aldrich, JR Saputelli, WS Mason, X Xu, ...
Antimicrobial agents and chemotherapy 56 (8), 4277-4288, 2012
2602012
Inhibition of hepatitis B virus replication by the host zinc finger antiviral protein
R Mao, H Nie, D Cai, J Zhang, H Liu, R Yan, A Cuconati, TM Block, ...
PLoS pathogens 9 (7), e1003494, 2013
2452013
Interferon induction of IFITM proteins promotes infection by human coronavirus OC43
X Zhao, F Guo, F Liu, A Cuconati, J Chang, TM Block, JT Guo
Proceedings of the National Academy of Sciences 111 (18), 6756-6761, 2014
1902014
Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids
MR Campagna, F Liu, R Mao, C Mills, D Cai, F Guo, X Zhao, H Ye, ...
Journal of virology 87 (12), 6931-6942, 2013
1792013
Complete Protein Linkage Map of Poliovirus P3 Proteins: Interaction of Polymerase 3Dpol with VPg and with Genetic Variants of 3AB
W Xiang, A Cuconati, D Hope, K Kirkegaard, E Wimmer
Journal of virology 72 (8), 6732-6741, 1998
1691998
Tumor necrosis factor-α induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K
R Sundararajan, A Cuconati, D Nelson, E White
Journal of Biological Chemistry 276 (48), 45120-45127, 2001
1592001
Regulation of hepatitis B virus replication by the phosphatidylinositol 3-kinase-akt signal transduction pathway
H Guo, T Zhou, D Jiang, A Cuconati, GH Xiao, TM Block, JT Guo
Journal of virology 81 (18), 10072-10080, 2007
1532007
Activation of pattern recognition receptor-mediated innate immunity inhibits the replication of hepatitis B virus in human hepatocyte-derived cells
H Guo, D Jiang, D Ma, J Chang, AM Dougherty, A Cuconati, TM Block, ...
Journal of virology 83 (2), 847-858, 2009
1462009
Chronic hepatitis B: what should be the goal for new therapies?
TM Block, R Gish, H Guo, A Mehta, A Cuconati, WT London, JT Guo
Antiviral research 98 (1), 27-34, 2013
1452013
Design, synthesis, and biological evaluation of triazolo-pyrimidine derivatives as novel inhibitors of hepatitis B virus surface antigen (HBsAg) secretion
W Yu, C Goddard, E Clearfield, C Mills, T Xiao, H Guo, JD Morrey, ...
Journal of medicinal chemistry 54 (16), 5660-5670, 2011
1432011
Indoleamine 2, 3-dioxygenase mediates the antiviral effect of gamma interferon against hepatitis B virus in human hepatocyte-derived cells
R Mao, J Zhang, D Jiang, D Cai, JM Levy, A Cuconati, TM Block, JT Guo, ...
Journal of virology 85 (2), 1048-1057, 2011
1422011
Bak and Bax function to limit adenovirus replication through apoptosis induction
A Cuconati, K Degenhardt, R Sundararajan, A Anschel, E White
Journal of virology 76 (9), 4547-4558, 2002
1282002
HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways
F Guo, Q Zhao, M Sheraz, J Cheng, Y Qi, Q Su, A Cuconati, L Wei, Y Du, ...
PLoS pathogens 13 (9), e1006658, 2017
1252017
Molecular dissection of the multifunctional poliovirus RNA-binding protein 3AB.
W Xiang, A Cuconati, AV Paul, X Cao, E Wimmer
Rna 1 (9), 892-904, 1995
1191995
Hepatitis B virus e antigen production is dependent upon covalently closed circular (ccc) DNA in HepAD38 cell cultures and may serve as a cccDNA surrogate in antiviral …
T Zhou, H Guo, JT Guo, A Cuconati, A Mehta, TM Block
Antiviral research 72 (2), 116-124, 2006
1182006
A substituted tetrahydro-tetrazolo-pyrimidine is a specific and novel inhibitor of hepatitis B virus surface antigen secretion
AM Dougherty, H Guo, G Westby, Y Liu, E Simsek, JT Guo, A Mehta, ...
Antimicrobial agents and chemotherapy 51 (12), 4427-4437, 2007
1082007
Brefeldin A inhibits cell-free, de novo synthesis of poliovirus
A Cuconati, A Molla, E Wimmer
Journal of virology 72 (8), 6456-6464, 1998
981998
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