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motoharu seiki
motoharu seiki
Div. Cancer Cell Research, Institute of Medical Science, University of Tokyo
Verified email at ims.u-tokyo.ac.jp - Homepage
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Year
A matrix metalloproteinase expressed on the surface of invasive tumour cells
H Sato, T Takino, Y Okada, J Cao, A Shinagawa, E Yamamoto, M Seiki
Nature 370 (6484), 61-65, 1994
32501994
Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA.
M Seiki, S Hattori, Y Hirayama, M Yoshida
Proceedings of the national academy of sciences 80 (12), 3618-3622, 1983
19371983
SRα promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus …
Y Takebe, M Seiki, JI Fujisawa, P Hoy, K Yokota, KI Arai, M Yoshida, ...
Molecular and cellular biology, 1988
17991988
Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules
E Ohuchi, K Imai, Y Fujii, H Sato, M Seiki, Y Okada
Journal of Biological Chemistry 272 (4), 2446-2451, 1997
12051997
Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease.
M Yoshida, M Seiki, K Yamaguchi, K Takatsuki
Proceedings of the National Academy of Sciences 81 (8), 2534-2537, 1984
10541984
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration
M Kajita, Y Itoh, T Chiba, H Mori, A Okada, H Kinoh, M Seiki
The Journal of cell biology 153 (5), 893-904, 2001
9282001
The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis
J Oh, R Takahashi, S Kondo, A Mizoguchi, E Adachi, RM Sasahara, ...
Cell 107 (6), 789-800, 2001
9172001
Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells.
H Sato, M Seiki
Oncogene 8 (2), 395-405, 1993
8691993
Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library: MT-MMPs form a unique membrane-type subclass in the MMP …
T Takino, H Sato, A Shinagawa, M Seiki
Journal of Biological Chemistry 270 (39), 23013-23020, 1995
6151995
Induction of interleukin 2 receptor gene expression by p40x encoded by human T‐cell leukemia virus type 1.
JL Inoue, M Seiki, T Taniguchi, S Tsuru, M Yoshida
The EMBO Journal 5 (11), 2883-2888, 1986
5941986
MT1‐MMP: a potent modifier of pericellular microenvironment
Y Itoh, M Seiki
Journal of cellular physiology 206 (1), 1-8, 2006
5702006
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion
H Nakahara, L Howard, EW Thompson, H Sato, M Seiki, Y Yeh, WT Chen
Proceedings of the National Academy of Sciences 94 (15), 7959-7964, 1997
5411997
Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion
M Seiki
Cancer letters 194 (1), 1-11, 2003
5262003
Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering
M Maruyama, H Shibuya, H Harada, M Hatakeyama, M Seiki, T Fujita, ...
Cell 48 (2), 343-350, 1987
5011987
Homophilic complex formation of MT1‐MMP facilitates proMMP‐2 activation on the cell surface and promotes tumor cell invasion
Y Itoh, A Takamura, N Ito, Y Maru, H Sato, N Suenaga, T Aoki, M Seiki
The EMBO journal, 2001
4972001
Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis
S Hiratsuka, Y Maru, A Okada, M Seiki, T Noda, M Shibuya
Cancer research 61 (3), 1207-1213, 2001
4902001
Activation of a recombinant membrane type 1‐matrix metalloproteinase (MT1‐MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)‐2
H Sato, T Kinoshita, T Takino, K Nakayama, M Seiki
FEBS letters 393 (1), 101-104, 1996
4781996
Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites …
R Gum, E Lengyel, J Juarez, JH Chen, H Sato, M Seiki, D Boyd
Journal of Biological Chemistry 271 (18), 10672-10680, 1996
4231996
Expression of membrane-type matrix metalloproteinase in human gastric carcinomas
H Nomura, H Sato, M Seiki, M Mai, Y Okada
Cancer Research 55 (15), 3263-3266, 1995
4211995
CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain
H Mori, T Tomari, N Koshikawa, M Kajita, Y Itoh, H Sato, H Tojo, I Yana, ...
The EMBO journal 21 (15), 3949-3959, 2002
4102002
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