‪Ernesto Lopes Pinheiro-Junior‬

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Eliane Candiani ArantesProfessora da Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São PauloVerified email at fcfrp.usp.br
Johara Boldrini FrançaSchool of Biochemistry, University of Bristol, Bristol, UKVerified email at uvv.br
Jan TytgatUniversity of Leuven (KU Leuven)Verified email at kuleuven.be
Steve PeigneurCatholic University Leuven (KU Leuven)Verified email at pharm.kuleuven.be
Manuela B. Pucca, Ph.DDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State UniversityVerified email at unesp.br
Fran CordeiroDoutoranda Verified email at fcfrp.usp.br
Karla de Castro Figueiredo BordonResearcher at University of São Paulo. MSc in Pharmaceutical Sciences, PhD in Sciences (Toxicology)Verified email at fcfrp.usp.br
Isadora Sousa de OliveiraPesquisadora de pós-doutorado na Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USPVerified email at alumni.usp.br
Gisele Adriano WiezelDoctor, University of São PauloVerified email at usp.br
Isabela Gobbo FerreiraUniversity of Sao PauloVerified email at alumni.usp.br
Marcos R M FontesSao Paulo State University - UNESPVerified email at ibb.unesp.br
Alexander VassilevskiHead of laboratory, Shemyakin-Ovchinnikov Institute of Bioorganic ChemistryVerified email at ibch.ru
Priscila Yumi Tanaka ShibaoPostdoc at University of BremenVerified email at uni-bremen.de
Lucija Peterlin MašičProffesor of medicinal chemistry and toxicologyVerified email at ffa.uni-lj.si
Tihomir TomasicUniversity of Ljubljana, Faculty of PharmacyVerified email at ffa.uni-lj.si
Lucia Helena FaccioliProfessor Titular de Imunologia, FCFRP - Universidade de São PauloVerified email at fcfrp.usp.br
Karina Furlani ZoccalFaculdade de Ciências Farmacêuticas, Universidade de São PauloVerified email at fcfrp.usp.br
Eduardo cilliInstituto de Química de Araraquara - UNESPVerified email at iq.unesp.br
Norival Alves Santos FilhoProfessor Assistente Doutor - Instituto de Química - UnespVerified email at unesp.br
Rafael Junqueira BorgesPostdoctorate Researcher of CQMED/UNICAMP (Campinas, São Paulo, Brazil)Verified email at unesp.br

Ernesto Lopes Pinheiro-Junior

Akkodis Belgium, Sanofi S.A.

Verified email at akkodis.com - Homepage

Drug development Biotechnology Electrophysiology PEGylation Recombinant proteins


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From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery KCF Bordon, CT Cologna, EC Fornari-Baldo, EL Pinheiro-Júnior, ... Frontiers in pharmacology, 1132, 2020	182	2020
Minor snake venom proteins: Structure, function and potential applications J Boldrini-França, CT Cologna, MB Pucca, KCF Bordon, FG Amorim, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4), 824-838, 2017	95	2017
Tityus serrulatus venom–A lethal cocktail MB Pucca, FA Cerni, ELP Junior, KCF Bordon, FG Amorim, FA Cordeiro, ... Toxicon 108, 272-284, 2015	85	2015
Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities J Boldrini-França, EL Pinheiro-Junior, S Peigneur, MB Pucca, FA Cerni, ... Scientific reports 10 (1), 1-11, 2020	35	2020
LmrBPP9: a synthetic bradykinin-potentiating peptide from Lachesis muta rhombeata venom that inhibits the angiotensin-converting enzyme activity in vitro and reduces the blood … EL Pinheiro-Junior, J Boldrini-França, LMP de Campos Araújo, ... Peptides 102, 1-7, 2018	21	2018
Kunitz-Type Peptides from the Sea Anemone Heteractis crispa Demonstrate Potassium Channel Blocking and Anti-Inflammatory Activities I Gladkikh, S Peigneur, O Sintsova, E Lopes Pinheiro-Junior, A Klimovich, ... Biomedicines 8 (11), 473, 2020	20	2020
Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors MB Pucca, FA Cerni, EL Pinheiro-Junior, KF Zoccal, KCF Bordon, ... Peptides 82, 44-51, 2016	17	2016
Functional and biological insights of rCollinein-1, a recombinant serine protease from Crotalus durissus collilineatus J Boldrini-França, EL Pinheiro-Junior, EC Arantes Journal of Venomous Animals and Toxins including Tropical Diseases 25, 2019	16	2019
Microbial production of toxins from the scorpion venom: properties and applications FG Amorim, FA Cordeiro, EL Pinheiro-Júnior, J Boldrini-França, ... Applied microbiology and biotechnology 102 (15), 6319-6331, 2018	14	2018
Apamin structure and pharmacology revisited AI Kuzmenkov, S Peigneur, JA Nasburg, KS Mineev, MV Nikolaev, ... Frontiers in Pharmacology 13, 977440, 2022	12	2022
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone ML Mitchell, MA Hossain, F Lin, EL Pinheiro-Junior, S Peigneur, DCC Wai, ... Biomolecules 11 (12), 1785, 2021	11	2021
Towards toxin PEGylation: The example of rCollinein-1, a snake venom thrombin-like enzyme, as a PEGylated biopharmaceutical prototype EL Pinheiro-Junior, J Boldrini-França, AAS Takeda, TR Costa, S Peigneur, ... International Journal of Biological Macromolecules 190, 564-573, 2021	10	2021
Tuning scorpion toxin selectivity: switching from KV1. 1 to KV1. 3 AM Gigolaev, AI Kuzmenkov, S Peigneur, VM Tabakmakher, ... Frontiers in Pharmacology 11, 551725, 2020	10	2020
Design of New Potent and Selective Thiophene-Based K_V1.3 Inhibitors and Their Potential for Anticancer Activity Š Gubič, LA Hendrickx, X Shi, Ž Toplak, Š Možina, KMV Theemsche, ... Cancers 14 (11), 2595, 2022	7	2022
Pioneering study on Rhopalurus crassicauda scorpion venom: isolation and characterization of the major toxin and hyaluronidase CB Abreu, KCF Bordon, FA Cerni, IS Oliveira, C Balenzuela, ... Frontiers in immunology 11, 560644, 2020	7	2020
A Tale of Toxin Promiscuity: The Versatile Pharmacological Effects of Hcr 1b-2 Sea Anemone Peptide on Voltage-Gated Ion Channels EL Pinheiro-Junior, R Kalina, I Gladkikh, E Leychenko, J Tytgat, ... Marine Drugs 20 (2), 147, 2022	6	2022
AsKC11, a Kunitz Peptide from Anemonia sulcata, Is a Novel Activator of G Protein-Coupled Inward-Rectifier Potassium Channels D An, EL Pinheiro-Junior, L Béress, I Gladkikh, E Leychenko, ... Marine Drugs 20 (2), 140, 2022	6	2022
Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica RS Kalina, IE Kasheverov, SG Koshelev, OV Sintsova, S Peigneur, ... Toxins 14 (10), 697, 2022	5	2022
Artificial Peptide Ligand of Potassium Channel KV 1.1 with High Selectivity VM Tabakmakher, AI Kuzmenkov, AM Gigolaev, EL Pinheiro-Junior, ... Journal of Evolutionary Biochemistry and Physiology 57 (2), 386-403, 2021	5	2021
New Diarylamine KV10. 1 Inhibitors and Their Anticancer Potential Š Gubič, Ž Toplak, X Shi, J Dernovšek, LA Hendrickx, EL Pinheiro-Junior, ... Pharmaceutics 14 (9), 1963, 2022	4	2022

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