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Eric Hajduch
Eric Hajduch
Chargé de Recherche INSERM
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Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCζ-dependent mechanism
DJ Powell, E Hajduch, G Kular, HS Hundal
Molecular and cellular biology 23 (21), 7794-7808, 2003
4422003
Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen …
E Hajduch, DR Alessi, BA Hemmings, HS Hundal
Diabetes 47 (7), 1006-1013, 1998
4261998
Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes
M Daval, F Diot-Dupuy, R Bazin, I Hainault, B Viollet, S Vaulont, ...
Journal of Biological Chemistry 280 (26), 25250-25257, 2005
4212005
Protein kinase B (PKB/Akt)–a key regulator of glucose transport?
E Hajduch, GJ Litherland, HS Hundal
FEBS letters 492 (3), 199-203, 2001
3882001
New insights into ER stress-induced insulin resistance
M Flamment, E Hajduch, P Ferré, F Foufelle
Trends in Endocrinology & Metabolism 23 (8), 381-390, 2012
3642012
Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells
DJ Powell, S Turban, A Gray, E Hajduch, HS Hundal
Biochemical Journal 382 (2), 619-629, 2004
3282004
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
E Hajduch, A Balendran, IH Batty, GJ Litherland, AS Blair, CP Downes, ...
Diabetologia 44, 173-183, 2001
2882001
L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the …
K PEYROLLIER, E HAJDUCH, AS BLAIR, R HYDE, HS HUNDAL
Biochemical Journal 350 (2), 361-368, 2000
2452000
Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase.
LG Fryer, E Hajduch, F Rencurel, IP Salt, HS Hundal, DG Hardie, ...
Diabetes 49 (12), 1978-1985, 2000
2362000
Cholesterol‐induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis
S Le Lay, E Hajduch, MR Lindsay, X Le Lièpvre, C Thiele, P Ferré, ...
Traffic 7 (5), 549-561, 2006
2152006
IL-1 receptor antagonist in metabolic diseases: Dr Jekyll or Mr Hyde?
S Perrier, F Darakhshan, E Hajduch
FEBS letters 580 (27), 6289-6294, 2006
2082006
Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress: evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated …
AS Blair, E Hajduch, GJ Litherland, HS Hundal
Journal of Biological Chemistry 274 (51), 36293-36299, 1999
2061999
Serotonin (5-hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle
E Hajduch, F Rencurel, A Balendran, IH Batty, CP Downes, HS Hundal
Journal of Biological Chemistry 274 (19), 13563-13568, 1999
1581999
Ceramide down‐regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells
R Hyde, E Hajduch, DJ Powell, PM Taylor, HS Hundal
The FASEB journal 19 (3), 1-24, 2005
1542005
Protein kinase C isoforms: mediators of reactive lipid metabolites in the development of insulin resistance
S Turban, E Hajduch
FEBS letters 585 (2), 269-274, 2011
1492011
Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner
GR Christie, E Hajduch, HS Hundal, CG Proud, PM Taylor
Journal of Biological Chemistry 277 (12), 9952-9957, 2002
1472002
Plasma membrane subdomain compartmentalization contributes to distinct mechanisms of ceramide action on insulin signaling
CM Blouin, C Prado, KK Takane, F Lasnier, A Garcia-Ocana, P Ferré, ...
Diabetes 59 (3), 600-610, 2010
1362010
Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide
E Hajduch, S Turban, X Le Liepvre, S Le Lay, C Lipina, N Dimopoulos, ...
Biochemical Journal 410 (2), 369-379, 2008
1352008
Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects [S]
CM Blouin, S Le Lay, A Eberl, HC Köfeler, IC Guerrera, C Klein, ...
Journal of lipid research 51 (5), 945-956, 2010
1322010
Fish oil in a high lard diet prevents obesity, hyperlipemia, and adipocyte insulin resistance in rats.
I Hainault, M Carlotti, E Hajduch, C Guichard, M Lavau
1281993
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