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Virpi Talman
Virpi Talman
PhD (Pharm) & docent, University of Helsinki, Finland
E-mail confirmado em helsinki.fi
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Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration
V Talman, H Ruskoaho
Cell and tissue research 365, 563-581, 2016
9172016
Cardiomyocyte—endothelial cell interactions in cardiac remodeling and regeneration
V Talman, R Kivelä
Frontiers in cardiovascular medicine 5, 101, 2018
1632018
Drug‐loaded multifunctional nanoparticles targeted to the endocardial layer of the injured heart modulate hypertrophic Signaling
MPA Ferreira, S Ranjan, S Kinnunen, A Correia, V Talman, E Mäkilä, ...
Small 13 (33), 1701276, 2017
1102017
Dual‐drug delivery using dextran‐functionalized nanoparticles targeting cardiac fibroblasts for cellular reprogramming
MPA Ferreira, V Talman, G Torrieri, D Liu, G Marques, K Moslova, Z Liu, ...
Advanced Functional Materials 28 (15), 1705134, 2018
762018
Design, synthesis, and biological activity of isophthalic acid derivatives targeted to the C1 domain of protein kinase C
GB af Gennas, V Talman, O Aitio, E Ekokoski, M Finel, RK Tuominen, ...
Journal of medicinal chemistry 52 (13), 3969-3981, 2009
742009
Molecular atlas of postnatal mouse heart development
V Talman, J Teppo, P Pöhö, P Movahedi, A Vaikkinen, ST Karhu, K Trošt, ...
Journal of the American Heart Association 7 (20), e010378, 2018
712018
Protein kinase C activation as a potential therapeutic strategy in Alzheimer's disease: is there a role for embryonic lethal abnormal vision‐like proteins?
V Talman, A Pascale, M Jäntti, M Amadio, RK Tuominen
Basic & clinical pharmacology & toxicology 119 (2), 149-160, 2016
642016
Cell adhesion and proliferation on common 3D printing materials used in stereolithography of microfluidic devices
K Piironen, M Haapala, V Talman, P Järvinen, T Sikanen
Lab on a Chip 20 (13), 2372-2382, 2020
602020
Discovery of small molecules targeting the synergy of cardiac transcription factors GATA4 and NKX2-5
MJ Välimäki, MA Tölli, SM Kinnunen, J Aro, R Serpi, L Pohjolainen, ...
Journal of Medicinal Chemistry 60 (18), 7781-7798, 2017
562017
Dual-peptide functionalized acetalated dextran-based nanoparticles for sequential targeting of macrophages during myocardial infarction
G Torrieri, F Fontana, P Figueiredo, Z Liu, MPA Ferreira, V Talman, ...
Nanoscale 12 (4), 2350-2358, 2020
502020
Current status and future prospects of C1 domain ligands as drug candidates
G Boije af Gennas, V Talman, J Yli-Kauhaluoma, R K Tuominen, ...
Current topics in medicinal chemistry 11 (11), 1370-1392, 2011
422011
Screening of natural compounds and their derivatives as potential protein kinase C inhibitors
P Tammela, E Ekokoski, A García‐Horsman, V Talman, M Finel, ...
Drug development research 63 (2), 76-87, 2004
382004
The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells
V Talman, M Amadio, C Osera, S Sorvari, GB af Gennäs, ...
Pharmacological Research 73, 44-54, 2013
312013
Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds
ST Karhu, MJ Välimäki, M Jumppanen, SM Kinnunen, L Pohjolainen, ...
Archives of Toxicology 92, 2897-2911, 2018
302018
C1 Domain-targeted isophthalate derivatives induce cell elongation and cell cycle arrest in HeLa cells
V Talman, RK Tuominen, GB Gennäs, J Yli-Kauhaluoma, E Ekokoski
PLoS One 6 (5), e20053, 2011
292011
Synthesis, identification, and structure–activity relationship analysis of GATA4 and NKX2-5 protein–protein interaction modulators
M Jumppanen, SM Kinnunen, MJ Välimäki, V Talman, S Auno, ...
Journal of Medicinal Chemistry 62 (17), 8284-8310, 2019
242019
GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human …
ST Karhu, SM Kinnunen, M Tölli, MJ Välimäki, Z Szabó, V Talman, ...
Archives of toxicology 94 (6), 2113-2130, 2020
222020
In Vitro Evaluation of the Therapeutic Effects of Dual‐Drug Loaded Spermine‐Acetalated Dextran Nanoparticles Coated with Tannic Acid for Cardiac Applications
G Torrieri, MPA Ferreira, MA Shahbazi, V Talman, ST Karhu, ...
Advanced Functional Materials 32 (5), 2109032, 2022
172022
Stereoselective synthesis of (3-aminodecahydro-1, 4-methanonaphthalen-2-yl) methanols targeted to the C1 domain of protein kinase C
A Kiriazis, GB af Gennäs, V Talman, E Ekokoski, T Ruotsalainen, ...
Tetrahedron 67 (45), 8665-8670, 2011
172011
Protein kinase C-activating isophthalate derivatives mitigate Alzheimer's disease-related cellular alterations
T Sarajärvi, M Jäntti, KMA Paldanius, T Natunen, JC Wu, P Mäkinen, ...
Neuropharmacology 141, 76-88, 2018
152018
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