Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration V Talman, H Ruskoaho Cell and tissue research 365, 563-581, 2016 | 917 | 2016 |
Cardiomyocyte—endothelial cell interactions in cardiac remodeling and regeneration V Talman, R Kivelä Frontiers in cardiovascular medicine 5, 101, 2018 | 163 | 2018 |
Drug‐loaded multifunctional nanoparticles targeted to the endocardial layer of the injured heart modulate hypertrophic Signaling MPA Ferreira, S Ranjan, S Kinnunen, A Correia, V Talman, E Mäkilä, ... Small 13 (33), 1701276, 2017 | 110 | 2017 |
Dual‐drug delivery using dextran‐functionalized nanoparticles targeting cardiac fibroblasts for cellular reprogramming MPA Ferreira, V Talman, G Torrieri, D Liu, G Marques, K Moslova, Z Liu, ... Advanced Functional Materials 28 (15), 1705134, 2018 | 76 | 2018 |
Design, synthesis, and biological activity of isophthalic acid derivatives targeted to the C1 domain of protein kinase C GB af Gennas, V Talman, O Aitio, E Ekokoski, M Finel, RK Tuominen, ... Journal of medicinal chemistry 52 (13), 3969-3981, 2009 | 74 | 2009 |
Molecular atlas of postnatal mouse heart development V Talman, J Teppo, P Pöhö, P Movahedi, A Vaikkinen, ST Karhu, K Trošt, ... Journal of the American Heart Association 7 (20), e010378, 2018 | 71 | 2018 |
Protein kinase C activation as a potential therapeutic strategy in Alzheimer's disease: is there a role for embryonic lethal abnormal vision‐like proteins? V Talman, A Pascale, M Jäntti, M Amadio, RK Tuominen Basic & clinical pharmacology & toxicology 119 (2), 149-160, 2016 | 64 | 2016 |
Cell adhesion and proliferation on common 3D printing materials used in stereolithography of microfluidic devices K Piironen, M Haapala, V Talman, P Järvinen, T Sikanen Lab on a Chip 20 (13), 2372-2382, 2020 | 60 | 2020 |
Discovery of small molecules targeting the synergy of cardiac transcription factors GATA4 and NKX2-5 MJ Välimäki, MA Tölli, SM Kinnunen, J Aro, R Serpi, L Pohjolainen, ... Journal of Medicinal Chemistry 60 (18), 7781-7798, 2017 | 56 | 2017 |
Dual-peptide functionalized acetalated dextran-based nanoparticles for sequential targeting of macrophages during myocardial infarction G Torrieri, F Fontana, P Figueiredo, Z Liu, MPA Ferreira, V Talman, ... Nanoscale 12 (4), 2350-2358, 2020 | 50 | 2020 |
Current status and future prospects of C1 domain ligands as drug candidates G Boije af Gennas, V Talman, J Yli-Kauhaluoma, R K Tuominen, ... Current topics in medicinal chemistry 11 (11), 1370-1392, 2011 | 42 | 2011 |
Screening of natural compounds and their derivatives as potential protein kinase C inhibitors P Tammela, E Ekokoski, A García‐Horsman, V Talman, M Finel, ... Drug development research 63 (2), 76-87, 2004 | 38 | 2004 |
The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells V Talman, M Amadio, C Osera, S Sorvari, GB af Gennäs, ... Pharmacological Research 73, 44-54, 2013 | 31 | 2013 |
Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds ST Karhu, MJ Välimäki, M Jumppanen, SM Kinnunen, L Pohjolainen, ... Archives of Toxicology 92, 2897-2911, 2018 | 30 | 2018 |
C1 Domain-targeted isophthalate derivatives induce cell elongation and cell cycle arrest in HeLa cells V Talman, RK Tuominen, GB Gennäs, J Yli-Kauhaluoma, E Ekokoski PLoS One 6 (5), e20053, 2011 | 29 | 2011 |
Synthesis, identification, and structure–activity relationship analysis of GATA4 and NKX2-5 protein–protein interaction modulators M Jumppanen, SM Kinnunen, MJ Välimäki, V Talman, S Auno, ... Journal of Medicinal Chemistry 62 (17), 8284-8310, 2019 | 24 | 2019 |
GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human … ST Karhu, SM Kinnunen, M Tölli, MJ Välimäki, Z Szabó, V Talman, ... Archives of toxicology 94 (6), 2113-2130, 2020 | 22 | 2020 |
In Vitro Evaluation of the Therapeutic Effects of Dual‐Drug Loaded Spermine‐Acetalated Dextran Nanoparticles Coated with Tannic Acid for Cardiac Applications G Torrieri, MPA Ferreira, MA Shahbazi, V Talman, ST Karhu, ... Advanced Functional Materials 32 (5), 2109032, 2022 | 17 | 2022 |
Stereoselective synthesis of (3-aminodecahydro-1, 4-methanonaphthalen-2-yl) methanols targeted to the C1 domain of protein kinase C A Kiriazis, GB af Gennäs, V Talman, E Ekokoski, T Ruotsalainen, ... Tetrahedron 67 (45), 8665-8670, 2011 | 17 | 2011 |
Protein kinase C-activating isophthalate derivatives mitigate Alzheimer's disease-related cellular alterations T Sarajärvi, M Jäntti, KMA Paldanius, T Natunen, JC Wu, P Mäkinen, ... Neuropharmacology 141, 76-88, 2018 | 15 | 2018 |