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Andrew M James
Andrew M James
E-mail confirmado em mrc-mbu.cam.ac.uk
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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ...
Nature 515 (7527), 431-435, 2014
24332014
Targeting an antioxidant to mitochondria decreases cardiac ischemia‐reperfusion injury
VJ Adlam, JC Harrison, CM Porteous, AM James, RAJ Smith, MP Murphy, ...
The FASEB Journal 19 (9), 1088-1095, 2005
7102005
A unifying mechanism for mitochondrial superoxide production during ischemia-reperfusion injury
ET Chouchani, VR Pell, AM James, LM Work, K Saeb-Parsy, C Frezza, ...
Cell metabolism 23 (2), 254-263, 2016
6712016
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I
ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ...
Nature medicine 19 (6), 753-759, 2013
6422013
Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology
MF Ross, GF Kelso, FH Blaikie, AM James, HM Cocheme, A Filipovska, ...
Biochemistry (Moscow) 70, 222-230, 2005
5482005
Interactions of Mitochondria-targeted and Untargeted Ubiquinones with the Mitochondrial Respiratory Chain and Reactive Oxygen Species: IMPLICATIONS FOR THE USE OF EXOGENOUS …
AM James, HM Cochemé, RAJ Smith, MP Murphy
Journal of Biological Chemistry 280 (22), 21295-21312, 2005
4522005
Antioxidant and prooxidant properties of mitochondrial Coenzyme Q
AM James, RAJ Smith, MP Murphy
Archives of biochemistry and biophysics 423 (1), 47-56, 2004
3712004
Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes
I Lopez-Fabuel, J Le Douce, A Logan, AM James, G Bonvento, ...
Proceedings of the National Academy of Sciences 113 (46), 13063-13068, 2016
3642016
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix
HM Cochemé, C Quin, SJ McQuaker, F Cabreiro, A Logan, TA Prime, ...
Cell metabolism 13 (3), 340-350, 2011
3192011
Mitochondrial redox signalling at a glance
Y Collins, ET Chouchani, AM James, KE Menger, HM Cochemé, ...
Journal of cell science 125 (4), 801-806, 2012
3142012
Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases
AM James, MS Sharpley, ARB Manas, FE Frerman, J Hirst, RAJ Smith, ...
Journal of Biological Chemistry 282 (20), 14708-14718, 2007
2672007
Fine-tuning the hydrophobicity of a mitochondria-targeted antioxidant
J Asin-Cayuela, ARB Manas, AM James, RAJ Smith, MP Murphy
FEBS letters 571 (1-3), 9-16, 2004
2512004
Control of mitochondrial superoxide production by reverse electron transport at complex I
EL Robb, AR Hall, TA Prime, S Eaton, M Szibor, C Viscomi, AM James, ...
Journal of Biological Chemistry 293 (25), 9869-9879, 2018
2502018
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice
S Rodriguez-Cuenca, HM Cochemé, A Logan, I Abakumova, TA Prime, ...
Free Radical Biology and Medicine 48 (1), 161-172, 2010
2392010
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury
TA Prime, FH Blaikie, C Evans, SM Nadtochiy, AM James, CC Dahm, ...
Proceedings of the National Academy of Sciences 106 (26), 10764-10769, 2009
2382009
How mitochondrial damage affects cell function
AM James, MP Murphy
Journal of biomedical science 9, 475-487, 2002
2312002
Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cells
MF Ross, TA Prime, I Abakumova, AM James, CM Porteous, RAJ Smith, ...
Biochemical Journal 411 (3), 633-645, 2008
2142008
Bioenergetic consequences of accumulating the common 4977‐bp mitochondrial DNA deletion
WK Porteous, AM James, PW Sheard, CM Porteous, MA Packer, ...
European Journal of Biochemistry 257 (1), 192-201, 1998
1961998
Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations
AM JAMES, YH WEI, CY PANG, MP MURPHY
Biochemical Journal 318 (2), 401-407, 1996
1951996
Quantitation and origin of the mitochondrial membrane potential in human cells lacking mitochondrial DNA
RD Appleby, WK Porteous, G Hughes, AM James, D Shannon, YH Wei, ...
European journal of biochemistry 262 (1), 108-116, 1999
1821999
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Artigos 1–20