| Novel 1,2,3-Triazole Derivatives for Use against Mycobacterium tuberculosis H37Rv (ATCC 27294) Strain N Boechat, VF Ferreira, SB Ferreira, MLG Ferreira, FC da Silva, ... Journal of Medicinal Chemistry 54 (17), 5988-5999, 2011 | 310 | 2011 |
| Chloroquine analogs as antimalarial candidates with potent in vitro and in vivo activity ACC Aguiar, E Murce, WA Cortopassi, AS Pimentel, MMFS Almeida, ... International Journal for Parasitology: Drugs and Drug Resistance 8 (3), 459-464, 2018 | 104 | 2018 |
| New approaches in antimalarial drug discovery and development: a review ACC Aguiar, EMM da Rocha, NB de Souza, TCC França, AU Krettli Memorias do Instituto Oswaldo Cruz 107, 831-845, 2012 | 103 | 2012 |
| New Compounds Hybrids 1H‐1,2,3‐Triazole‐Quinoline Against Plasmodium falciparum N Boechat, MLG Ferreira, LCS Pinheiro, AML Jesus, MMM Leite, ... Chemical Biology & Drug Design 84 (3), 325-332, 2014 | 81 | 2014 |
| Ethnopharmacological evaluation of medicinal plants used against malaria by quilombola communities from Oriximiná, Brazil DR Oliveira, AU Krettli, ACC Aguiar, GG Leitão, MN Vieira, KS Martins, ... Journal of ethnopharmacology 173, 424-434, 2015 | 71 | 2015 |
| New Trifluoromethyl Triazolopyrimidines as Anti-Plasmodiumfalciparum Agents N Boechat, LCS Pinheiro, TS Silva, ACC Aguiar, AS Carvalho, MM Bastos, ... Molecules 17 (7), 8285-8302, 2012 | 70 | 2012 |
| Antimalarial activity and mechanisms of action of two novel 4-aminoquinolines against chloroquine-resistant parasites ACC Aguiar, RM Santos, FJB Figueiredo, WA Cortopassi, AS Pimentel, ... PLoS One 7 (5), e37259, 2012 | 70 | 2012 |
| Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum TPC Chierrito, ACC Aguiar, IM de Andrade, IP Ceravolo, RAC Gonçalves, ... Malaria journal 13, 1-10, 2014 | 66 | 2014 |
| Isolation, Derivative Synthesis, and Structure–Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis LLL Parra, AF Bertonha, IRM Severo, ACC Aguiar, GE de Souza, G Oliva, ... Journal of natural products 81 (1), 188-202, 2018 | 53 | 2018 |
| Discovery of Marinoquinolines as Potent and Fast-Acting Plasmodium falciparum Inhibitors with in Vivo Activity ACC Aguiar, M Panciera, EF Simao dos Santos, MK Singh, ML Garcia, ... Journal of medicinal chemistry 61 (13), 5547-5568, 2018 | 52 | 2018 |
| Distinctive genetic structure and selection patterns in Plasmodium vivax from South Asia and East Africa ED Benavente, E Manko, J Phelan, M Campos, D Nolder, D Fernandez, ... Nature communications 12 (1), 3160, 2021 | 39 | 2021 |
| Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti-malarials and gene characterization in Rondônia, West Amazon, Brazil ACC Aguiar, DB Pereira, NS Amaral, L De Marco, AU Krettli Malaria journal 13, 1-7, 2014 | 39 | 2014 |
| Aspidosperma (Apocynaceae) plant cytotoxicity and activity towards malaria parasites. Part I: Aspidosperma nitidum (Benth) used as a remedy to treat fever and malaria in the Amazon JP Coutinho, ACC Aguiar, PA Santos, JC Lima, MGL Rocha, CL Zani, ... Memórias do Instituto Oswaldo Cruz 108, 974-982, 2013 | 32 | 2013 |
| Antimalarial Activity of Cocos nucifera Husk Fibre: Further Studies JO Adebayo, EA Balogun, SO Malomo, AO Soladoye, LA Olatunji, ... Evidence-Based Complementary and Alternative Medicine 2013, 2013 | 31 | 2013 |
| Chemical composition, antiprotozoal and cytotoxic activities of indole alkaloids and benzofuran neolignan of Aristolochia cordigera MDP Pereira, T da Silva, ACC Aguiar, G Oliva, RVC Guido, ... Planta medica 83 (11), 912-920, 2017 | 30 | 2017 |
| Evaluation of antimalarial activity and toxicity of a new primaquine prodrug MG Davanco, ACC Aguiar, LA Dos Santos, EC Padilha, ML Campos, ... Plos one 9 (8), e105217, 2014 | 30 | 2014 |
| Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series MJ Palmer, X Deng, S Watts, G Krilov, A Gerasyuto, S Kokkonda, ... Journal of medicinal chemistry 64 (9), 6085-6136, 2021 | 29 | 2021 |
| Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors FF Silveira, JO de Souza, LVB Hoelz, VR Campos, VAP Jabor, ... European Journal of Medicinal Chemistry 209, 112941, 2021 | 27 | 2021 |
| New hybrid trifluoromethylquinolines as antiplasmodium agents RMRJ da Silva, MO Gandi, JS Mendonça, AS Carvalho, JP Coutinho, ... Bioorganic & Medicinal Chemistry 27 (6), 1002-1008, 2019 | 26 | 2019 |
| BbMP-1, a new metalloproteinase isolated from Bothrops brazili snake venom with in vitro antiplasmodial properties AM Kayano, R Simoes-Silva, PSM Medeiros, VG Maltarollo, KM Honorio, ... Toxicon 106, 30-41, 2015 | 26 | 2015 |
