Tet3 reads 5-carboxylcytosine through its CXXC domain and is a potential guardian against neurodegeneration SG Jin, ZM Zhang, TL Dunwell, MR Harter, X Wu, J Johnson, Z Li, J Liu, ... Cell reports 14 (3), 493-505, 2016 | 156 | 2016 |
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells SW Paugh, EJ Bonten, D Savic, LB Ramsey, WE Thierfelder, P Gurung, ... Nature genetics 47 (6), 607-614, 2015 | 156 | 2015 |
Epigenetic analysis of childhood acute lymphoblastic leukemia TL Dunwell, LB Hesson, TV Pavlova, V Zabarovska, VI Kashuba, ... Epigenetics 4 (3), 185-193, 2009 | 149 | 2009 |
A genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers T Dunwell, L Hesson, TA Rauch, L Wang, RE Clark, A Dallol, D Gentle, ... Molecular cancer 9, 1-12, 2010 | 126 | 2010 |
The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias LB Hesson, TL Dunwell, WN Cooper, D Catchpoole, AT Brini, ... Molecular cancer 8, 1-10, 2009 | 126 | 2009 |
New genes from old: asymmetric divergence of gene duplicates and the evolution of development PWH Holland, F Marlétaz, I Maeso, TL Dunwell, J Paps Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017 | 109 | 2017 |
The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-κB signaling pathways FE Lock, N Underhill-Day, T Dunwell, D Matallanas, W Cooper, L Hesson, ... Oncogene 29 (30), 4307-4316, 2010 | 94 | 2010 |
Frequent epigenetic inactivation of the SLIT2 gene in chronic and acute lymphocytic leukemia TL Dunwell, RE Dickinson, T Stankovic, A Dallol, V Weston, B Austen, ... Epigenetics 4 (4), 265-269, 2009 | 69 | 2009 |
Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell … VK Hill, TL Dunwell, D Catchpoole, D Krex, AT Brini, M Griffiths, ... Epigenetics 6 (3), 326-332, 2011 | 55 | 2011 |
Salvador protein is a tumor suppressor effector of RASSF1A with hippo pathway-independent functions H Donninger, N Allen, A Henson, J Pogue, A Williams, L Gordon, ... Journal of Biological Chemistry 286 (21), 18483-18491, 2011 | 49 | 2011 |
The mysterious presence of a 5-methylcytosine oxidase in the Drosophila genome: Possible explanations TL Dunwell, LJ McGuffin, JM Dunwell, GP Pfeifer Cell cycle 12 (21), 3357-3365, 2013 | 44 | 2013 |
Drosophila genomic methylation: new evidence and new questions TL Dunwell, GP Pfeifer Epigenomics 6 (5), 459-461, 2014 | 43 | 2014 |
Evolutionary origin and functional divergence of totipotent cell homeobox genes in eutherian mammals I Maeso, TL Dunwell, CDR Wyatt, F Marlétaz, B Vető, JA Bernal, S Quah, ... BMC biology 14, 1-14, 2016 | 42 | 2016 |
High expression of new genes in trochophore enlightening the ontogeny and evolution of trochozoans F Xu, T Domazet-Lošo, D Fan, TL Dunwell, L Li, X Fang, G Zhang Scientific reports 6 (1), 34664, 2016 | 41 | 2016 |
Detection of oxidation products of 5-methyl-2′-deoxycytidine in Arabidopsis DNA S Liu, TL Dunwell, GP Pfeifer, JM Dunwell, I Ullah, Y Wang PLoS One 8 (12), e84620, 2013 | 35 | 2013 |
Novel and divergent genes in the evolution of placental mammals TL Dunwell, J Paps, PWH Holland Proceedings of the Royal Society B: Biological Sciences 284 (1864), 20171357, 2017 | 31 | 2017 |
Diversity of human and mouse homeobox gene expression in development and adult tissues TL Dunwell, PWH Holland BMC developmental biology 16, 1-9, 2016 | 28 | 2016 |
Genome-wide mapping of 5-hydroxymethylcytosine in three rice cultivars reveals its preferential localization in transcriptionally silent transposable element genes X Wang, S Song, YS Wu, YL Li, T Chen, Z Huang, S Liu, TL Dunwell, ... Journal of Experimental Botany 66 (21), 6651-6663, 2015 | 28 | 2015 |
Nano-scale gene delivery systems: current technology, obstacles, and future directions A Garcia-Guerra, TL Dunwell, S Trigueros Current medicinal chemistry 25 (21), 2448-2464, 2018 | 21 | 2018 |
Mouse Obox and Crxos modulate preimplantation transcriptional profiles revealing similarity between paralogous mouse and human homeobox genes AH Royall, I Maeso, TL Dunwell, PWH Holland Evodevo 9, 1-14, 2018 | 16 | 2018 |