Fe-catalysed oxidative C–H functionalization/C–S bond formation H Wang, L Wang, J Shang, X Li, H Wang, J Gui, A Lei Chemical communications 48 (1), 76-78, 2012 | 239 | 2012 |
REV-ERBα regulates TH17 cell development and autoimmunity M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, ... Cell reports 25 (13), 3733-3749. e8, 2018 | 90 | 2018 |
Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ J Shang, R Brust, SA Mosure, J Bass, P Munoz-Tello, H Lin, TS Hughes, ... Elife 7, e43320, 2018 | 69 | 2018 |
Identification of a binding site for unsaturated fatty acids in the orphan nuclear receptor Nurr1 IMS de Vera, PK Giri, P Munoz-Tello, R Brust, J Fuhrmann, ... ACS chemical biology 11 (7), 1795-1799, 2016 | 66 | 2016 |
Defining a conformational ensemble that directs activation of PPARγ IM Chrisman, MD Nemetchek, IMS De Vera, J Shang, Z Heidari, Y Long, ... Nature communications 9 (1), 1794, 2018 | 63 | 2018 |
A structural mechanism for directing corepressor-selective inverse agonism of PPARγ R Brust, J Shang, J Fuhrmann, SA Mosure, J Bass, A Cano, Z Heidari, ... Nature communications 9 (1), 4687, 2018 | 58 | 2018 |
A molecular switch regulating transcriptional repression and activation of PPARγ J Shang, SA Mosure, J Zheng, R Brust, J Bass, A Nichols, LA Solt, ... Nature Communications 11 (1), 956, 2020 | 52 | 2020 |
Synergistic regulation of coregulator/nuclear receptor interaction by ligand and DNA IMS de Vera, J Zheng, S Novick, J Shang, TS Hughes, R Brust, ... Structure 25 (10), 1506-1518. e4, 2017 | 51 | 2017 |
Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1 IMS de Vera, P Munoz-Tello, J Zheng, V Dharmarajan, DP Marciano, ... Structure 27 (1), 66-77. e5, 2019 | 45 | 2019 |
CAR directs T cell adaptation to bile acids in the small intestine ML Chen, X Huang, H Wang, C Hegner, Y Liu, J Shang, A Eliason, H Diao, ... Nature 593 (7857), 147-151, 2021 | 41 | 2021 |
Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the antidiabetic PPARγ drug pioglitazone SA Mosure, J Shang, J Eberhardt, R Brust, J Zheng, PR Griffin, S Forli, ... Journal of medicinal chemistry 62 (4), 2008-2023, 2019 | 31 | 2019 |
Chemical crosslinking mass spectrometry reveals the conformational landscape of the activation helix of PPARγ; a model for ligand-dependent antagonism J Zheng, C Corzo, MR Chang, J Shang, VQ Lam, R Brust, AL Blayo, ... Structure 26 (11), 1431-1439. e6, 2018 | 29 | 2018 |
Structural mechanism underlying ligand binding and activation of PPARγ J Shang, DJ Kojetin Structure 29 (9), 940-950. e4, 2021 | 24 | 2021 |
Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl … TS Hughes, J Shang, R Brust, IMS de Vera, J Fuhrmann, C Ruiz, ... Journal of medicinal chemistry 59 (22), 10335-10341, 2016 | 24 | 2016 |
Quantitative structural assessment of graded receptor agonism J Shang, R Brust, PR Griffin, TM Kameneck, DJ Kojetin Proceedings of the National Academy of Sciences 116 (44), 22179-22188, 2019 | 22 | 2019 |
Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ SA Mosure, TS Strutzenberg, J Shang, P Munoz-Tello, LA Solt, PR Griffin, ... Science advances 7 (5), eabc6479, 2021 | 18 | 2021 |
Structure of the FP domain of Fbxo7 reveals a novel mode of protein–protein interaction J Shang, G Wang, Y Yang, X Huang, Z Du Acta Crystallographica Section D: Biological Crystallography 70 (1), 155-164, 2014 | 11 | 2014 |
The FP Domains of PI31 and Fbxo7 have the same Protein Fold but very Different Modes of Protein–Protein Interaction ZD Jinsai Shang, Xiaolan Huang The FASEB Journal 29 (1), Supplement 883.4, 2015 | 8* | 2015 |
Expression, purification and crystallization of the FP domain of the human F-box protein Fbxo7 J Shang, G Wang, Y Yang, X Huang, Z Du Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 5 | 2013 |
Molecular basis of ligand-dependent Nurr1-RXRα activation X Yu, J Shang, DJ Kojetin Elife 12, e85039, 2023 | 3 | 2023 |