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Adam Boxer
Adam Boxer
UCSF Memory and Aging Center
E-mail confirmado em ucsf.edu
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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
M DeJesus-Hernandez, IR Mackenzie, BF Boeve, AL Boxer, M Baker, ...
Neuron 72 (2), 245-256, 2011
52712011
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
21662019
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ...
Nature genetics 43 (5), 436-441, 2011
21342011
Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria
GU Höglinger, G Respondek, M Stamelou, C Kurz, KA Josephs, AE Lang, ...
Movement disorders 32 (6), 853-864, 2017
16642017
Criteria for the diagnosis of corticobasal degeneration
MJ Armstrong, I Litvan, AE Lang, TH Bak, KP Bhatia, B Borroni, AL Boxer, ...
Neurology 80 (5), 496-503, 2013
16592013
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
S Ray, M Britschgi, C Herbert, Y Takeda-Uchimura, A Boxer, K Blennow, ...
Nature medicine 13 (11), 1359-1362, 2007
12772007
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
Y Shi, K Yamada, SA Liddelow, ST Smith, L Zhao, W Luo, RM Tsai, ...
Nature 549 (7673), 523-527, 2017
9772017
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
8982017
Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: a case‐control study
MS Fiandaca, D Kapogiannis, M Mapstone, A Boxer, E Eitan, JB Schwartz, ...
Alzheimer's & Dementia 11 (6), 600-607. e1, 2015
7962015
At the interface of sensory and motor dysfunctions and Alzheimer's disease
MW Albers, GC Gilmore, J Kaye, C Murphy, A Wingfield, DA Bennett, ...
Alzheimer's & Dementia 11 (1), 70-98, 2015
5572015
Diagnostic value of cerebrospinal fluid neurofilament light protein in neurology: a systematic review and meta-analysis
C Bridel, WN Van Wieringen, H Zetterberg, BM Tijms, CE Teunissen, ...
JAMA neurology 76 (9), 1035-1048, 2019
5422019
Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration
EH Thijssen, R La Joie, A Wolf, A Strom, P Wang, L Iaccarino, ...
Nature medicine 26 (3), 387-397, 2020
5202020
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes
G Jun, AC Naj, GW Beecham, LS Wang, J Buros, PJ Gallins, JD Buxbaum, ...
Archives of neurology 67 (12), 1473-1484, 2010
4962010
Clinicopathological correlations in corticobasal degeneration
SE Lee, GD Rabinovici, MC Mayo, SM Wilson, WW Seeley, SJ DeArmond, ...
Annals of neurology 70 (2), 327-340, 2011
4502011
Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease
EJ Goetzl, A Boxer, JB Schwartz, EL Abner, RC Petersen, BL Miller, ...
Neurology 85 (1), 40-47, 2015
4222015
Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
S Almeida, E Gascon, H Tran, HJ Chou, TF Gendron, S DeGroot, ...
Acta neuropathologica 126, 385-399, 2013
3942013
Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy
AL Boxer, MD Geschwind, N Belfor, ML Gorno-Tempini, GF Schauer, ...
Archives of neurology 63 (1), 81-86, 2006
3692006
Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation
S Villeneuve, GD Rabinovici, BI Cohn-Sheehy, C Madison, N Ayakta, ...
Brain 138 (7), 2020-2033, 2015
3682015
Advances in progressive supranuclear palsy: new diagnostic criteria, biomarkers, and therapeutic approaches
AL Boxer, JT Yu, LI Golbe, I Litvan, AE Lang, GU Höglinger
The Lancet Neurology 16 (7), 552-563, 2017
3562017
Discriminative accuracy of [18F] flortaucipir positron emission tomography for Alzheimer disease vs other neurodegenerative disorders
R Ossenkoppele, GD Rabinovici, R Smith, H Cho, M Schöll, O Strandberg, ...
Jama 320 (11), 1151-1162, 2018
3532018
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