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Una O'Doherty
Una O'Doherty
Associate Professor, Upenn
E-mail confirmado em mail.med.upenn.edu
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Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature.
U O'doherty, M Peng, S Gezelter, WJ Swiggard, M Betjes, N Bhardwaj, ...
Immunology 82 (3), 487, 1994
8771994
Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
U O'Doherty, WJ Swiggard, MH Malim
Journal of virology 74 (21), 10074-10080, 2000
8552000
Clinical use of lentiviral vectors
MC Milone, U O’Doherty
Leukemia 32 (7), 1529-1541, 2018
7772018
Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies
S Eriksson, EH Graf, V Dahl, MC Strain, SA Yukl, ES Lysenko, RJ Bosch, ...
PLoS pathogens 9 (2), e1003174, 2013
6652013
Towards an HIV cure: a global scientific strategy
Nature reviews Immunology 12 (8), 607-614, 2012
6062012
Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.
U O'doherty, RM Steinman, M Peng, PU Cameron, S Gezelter, I Kopeloff, ...
The Journal of experimental medicine 178 (3), 1067-1076, 1993
4881993
Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy
H Imamichi, RL Dewar, JW Adelsberger, CA Rehm, U O’doherty, ...
Proceedings of the National Academy of Sciences 113 (31), 8783-8788, 2016
3542016
A novel assay to measure the magnitude of the inducible viral reservoir in HIV-infected individuals
FA Procopio, R Fromentin, DA Kulpa, JH Brehm, AG Bebin, MC Strain, ...
EBioMedicine 2 (8), 874-883, 2015
3052015
Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors
A Granelli-Piperno, B Moser, M Pope, D Chen, Y Wei, F Isdell, ...
The Journal of experimental medicine 184 (6), 2433-2438, 1996
3011996
A sensitive, quantitative assay for human immunodeficiency virus type 1 integration
U O'Doherty, WJ Swiggard, D Jeyakumar, D McGain, MH Malim
Journal of virology 76 (21), 10942-10950, 2002
2932002
cis Expression of DC-SIGN Allows for More Efficient Entry of Human and Simian Immunodeficiency Viruses via CD4 and a Coreceptor
B Lee, G Leslie, E Soilleux, U O'Doherty, S Baik, E Levroney, ...
Journal of virology 75 (24), 12028-12038, 2001
2572001
Human Immunodeficiency Virus Type 1 Can Establish Latent Infection in Resting CD4+ T Cells in the Absence of Activating Stimuli
WJ Swiggard, C Baytop, JJ Yu, J Dai, C Li, R Schretzenmair, ...
Journal of virology 79 (22), 14179-14188, 2005
2432005
Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration
L Azzoni, AS Foulkes, E Papasavvas, AM Mexas, KM Lynn, K Mounzer, ...
The Journal of infectious diseases 207 (2), 213-222, 2013
2202013
Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR
MK Liszewski, JY Jianqing, U O’Doherty
Methods 47 (4), 254-260, 2009
1932009
HIV integration site distributions in resting and activated CD4+ T cells infected in culture
T Brady, LM Agosto, N Malani, CC Berry, U O'Doherty, F Bushman
Aids 23 (12), 1461-1471, 2009
1822009
Directly infected resting CD4+ T cells can produce HIV Gag without spreading infection in a model of HIV latency
MJ Pace, EH Graf, LM Agosto, AM Mexas, F Male, T Brady, FD Bushman, ...
PLoS pathogens 8 (7), e1002818, 2012
1632012
Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART
EH Graf, AM Mexas, JJ Yu, F Shaheen, MK Liszewski, M Di Mascio, ...
PLoS pathogens 7 (2), e1001300, 2011
1602011
Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion
MR Pinzone, DJ VanBelzen, S Weissman, MP Bertuccio, LM Cannon, ...
Nature communications 10 (1), 728, 2019
1552019
HIV reservoirs and latency models
MJ Pace, L Agosto, EH Graf, U O'Doherty
Virology 411 (2), 344-354, 2011
1492011
A novel monoclonal antibody against human Argonaute proteins reveals unexpected characteristics of miRNAs in human blood cells
PT Nelson, M De Planell-Saguer, S Lamprinaki, M Kiriakidou, P Zhang, ...
Rna 13 (10), 1787-1792, 2007
1472007
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