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David Gordon
David Gordon
E-mail confirmado em ndcn.ox.ac.uk
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Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltration
D Gordon, G Pavlovska, CP Glover, JB Uney, D Wraith, NJ Scolding
Neuroscience letters 448 (1), 71-73, 2008
1582008
Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesis
BL Conway-Campbell, JW Wooh, AJ Brooks, D Gordon, RJ Brown, ...
Proceedings of the National Academy of Sciences 104 (33), 13331-13336, 2007
1262007
Human mesenchymal stem cells infiltrate the spinal cord, reduce demyelination, and localize to white matter lesions in experimental autoimmune encephalomyelitis
D Gordon, G Pavlovska, JB Uney, DC Wraith, NJ Scolding
Journal of Neuropathology & Experimental Neurology 69 (11), 1087-1095, 2010
1172010
Fusion between human mesenchymal stem cells and rodent cerebellar Purkinje cells
K Kemp, D Gordon, DC Wraith, E Mallam, E Hartfield, J Uney, A Wilkins, ...
Neuropathology and applied neurobiology 37 (2), 166-178, 2011
1002011
TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca2+ signaling in motor neurons
R Mutihac, J Alegre-Abarrategui, D Gordon, L Farrimond, ...
Neurobiology of disease 75, 64-77, 2015
662015
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor …
D Gordon, R Dafinca, J Scaber, J Alegre-Abarrategui, L Farrimond, ...
Neurobiology of disease 121, 148-162, 2019
602019
Mice carrying ALS mutant TDP-43, but not mutant FUS, display in vivo defects in axonal transport of signaling endosomes
JN Sleigh, AP Tosolini, D Gordon, A Devoy, P Fratta, EMC Fisher, ...
Cell Reports 30 (11), 3655-3662. e2, 2020
532020
An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress
E Feneberg, D Gordon, AG Thompson, MJ Finelli, R Dafinca, A Candalija, ...
Neurobiology of disease 144, 105050, 2020
252020
Human mesenchymal stem cell culture for neural transplantation
D Gordon, NJ Scolding
Neural Cell Transplantation: Methods and Protocols, 103-118, 2009
242009
Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo
MG Williamson, MJ Finelli, JN Sleigh, A Reddington, D Gordon, K Talbot, ...
Human Molecular Genetics 28 (21), 3584-3599, 2019
222019
Enhanced green fluorescent protein-expressing human mesenchymal stem cells retain neural marker expression
D Gordon, CP Glover, AM Merrison, JB Uney, NJ Scolding
Journal of neuroimmunology 193 (1-2), 59-67, 2008
222008
Antisense suppression of tau in cultured rat oligodendrocytes inhibits process formation
D Gordon, GJ Kidd, R Smith
Journal of neuroscience research 86 (12), 2591-2601, 2008
172008
Stress granule assembly in vivo is deficient in the CNS of mutant TDP-43 ALS mice
A Dubinski, M Gagné, S Peyrard, D Gordon, K Talbot, C Vande Velde
Human Molecular Genetics 32 (2), 319-332, 2023
82023
ALS mice carrying pathological mutant TDP-43, but not mutant FUS, display axonal transport defects in vivo
JN Sleigh, AP Tosolini, D Gordon, A Devoy, P Fratta, EMC Fisher, ...
BioRxiv, 438812, 2018
72018
TDP-43 is cytoplasmically mislocalized and associated with impaired stress responses and survival of primary neurons from symptomatic amyotrophic lateral sclerosis (ALS) mice
L Farrimond, D Gordon, R Mutihac, J Alegre-Abarrategui, B Davies, ...
EUROPEAN JOURNAL OF NEUROLOGY 23, 390-391, 2016
2016
Absence of wide-spread mis-splicing in the preclinical phase of a native promoter driven TDP-43 mouse model of ALS
J Scaber, D Gordon, R Mutihac, J Alegre-Abarrategui, J Riancho, D Sims, ...
NEUROMUSCULAR DISORDERS 26, S31-S31, 2016
2016
Motor disorders
D Gordon, K Talbot
Behavioral Genetics of the Mouse: Volume 2, Genetic Mouse Models of …, 2014
2014
Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis (P3. 012)
K Talbot, D Gordon, R Mutihac, J Alegre-Abarrategui, L Farrimond, ...
Neurology 82 (10_supplement), P3. 012, 2014
2014
Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis (I11-1.007)
K Talbot, D Gordon, R Mutihac, J Alegre-Abarrategui, L Farrimond, ...
Neurology 82 (10 Supplement), 2014
2014
Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis (I11-1.007)
K Talbot, D Gordon, R Mutihac, J Alegre-Abarrategui, L Farrimond, ...
Neurology 82 (10 Supplement), 2014
2014
O sistema não pode executar a operação agora. Tente novamente mais tarde.
Artigos 1–20