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Natasha M. Kablaoui
Natasha M. Kablaoui
E-mail confirmado em novartis.com
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Titanocene-catalyzed cyclocarbonylation of enynes to cyclopentenones
FA Hicks, NM Kablaoui, SL Buchwald
Journal of the American Chemical Society 118 (39), 9450-9451, 1996
1841996
Scope of the Intramolecular Titanocene-Catalyzed Pauson−Khand Type Reaction1
FA Hicks, NM Kablaoui, SL Buchwald
Journal of the American Chemical Society 121 (25), 5881-5898, 1999
1521999
A titanocene-catalyzed intramolecular ene reaction: Cycloisomerization of enynes and dienynes
SJ Sturla, NM Kablaoui, SL Buchwald
Journal of the American Chemical Society 121 (9), 1976-1977, 1999
1441999
Reductive cyclization of enones by a titanium catalyst
NM Kablaoui, SL Buchwald
Journal of the American Chemical Society 117 (25), 6785-6786, 1995
1251995
Titanocene-Catalyzed Cyclocarbonylation of o-Allyl Aryl Ketones to γ-Butyrolactones
NM Kablaoui, FA Hicks, SL Buchwald
Journal of the American Chemical Society 119 (19), 4424-4431, 1997
1181997
Diastereoselective synthesis of γ-butyrolactones from enones mediated or catalyzed by a titanocene complex
NM Kablaoui, FA Hicks, SL Buchwald
Journal of the American Chemical Society 118 (24), 5818-5819, 1996
1171996
Development of a Method for the Reductive Cyclization of Enones by a Titanium Catalyst
NM Kablaoui, SL Buchwald
Journal of the American Chemical Society 118 (13), 3182-3191, 1996
1161996
Identification of small-molecule inhibitors of the JIP–JNK interaction
T Chen, N Kablaoui, J Little, S Timofeevski, WR Tschantz, P Chen, J Feng, ...
Biochemical Journal 420 (2), 283-296, 2009
672009
Quinazolin-4-piperidin-4-methyl sulfamide PC-1 inhibitors: Alleviating hERG interactions through structure based design
SD Patel, WM Habeski, AC Cheng, E de la Cruz, C Loh, NM Kablaoui
Bioorganic & medicinal chemistry letters 19 (12), 3339-3343, 2009
592009
Discovery of novel, potent, and selective inhibitors of 3-phosphoinositide-dependent kinase (PDK1)
ST Murphy, G Alton, S Bailey, SM Baxi, BJ Burke, TA Chappie, J Ermolieff, ...
Journal of medicinal chemistry 54 (24), 8490-8500, 2011
382011
Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design
DP Walker, GB Arhancet, HF Lu, SE Heasley, S Metz, NM Kablaoui, ...
Bioorganic & medicinal chemistry letters 23 (4), 1120-1126, 2013
312013
Systematic N-methylation of oxytocin: Impact on pharmacology and intramolecular hydrogen bonding network
S Sciabola, GH Goetz, G Bai, BN Rogers, DL Gray, A Duplantier, ...
Bioorganic & Medicinal Chemistry 24 (16), 3513-3520, 2016
302016
Novel benzoxazole inhibitors of mPGES-1
N Kablaoui, S Patel, J Shao, D Demian, K Hoffmaster, F Berlioz, ...
Bioorganic & medicinal chemistry letters 23 (3), 907-911, 2013
292013
Peripheral administration of a long-acting peptide oxytocin receptor agonist inhibits fear-induced freezing
ME Modi, MJ Majchrzak, KR Fonseca, A Doran, S Osgood, ...
Journal of Pharmacology and Experimental Therapeutics 358 (2), 164-172, 2016
282016
Comparative pharmacokinetic profile of cyclosporine (CsA) with a decapeptide and a linear analogue
DA Price, H Eng, KA Farley, GH Goetz, Y Huang, Z Jiao, AS Kalgutkar, ...
Organic & Biomolecular Chemistry 15 (12), 2501-2506, 2017
222017
Potent and selective thiophene urea-templated inhibitors of S6K
P Ye, C Kuhn, M Juan, R Sharma, B Connolly, G Alton, H Liu, R Stanton, ...
Bioorganic & medicinal chemistry letters 21 (2), 849-852, 2011
192011
Identification and SAR around N-{2-[4-(2, 3-dihydro-benzo [1, 4] dioxin-2-ylmethyl)-[1, 4] diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective α2C adrenergic receptor …
SD Patel, WM Habeski, H Min, J Zhang, R Roof, B Snyder, G Bora, ...
Bioorganic & medicinal chemistry letters 18 (20), 5689-5693, 2008
122008
Hybrid peptide-small molecule oxytocin analogs are potent and selective agonists of the oxytocin receptor
N Kablaoui, M Vanase-Frawley, S Sciabola
Bioorganic & Medicinal Chemistry Letters 28 (3), 415-419, 2018
112018
Discovery of selective M4 muscarinic acetylcholine receptor agonists with novel carbamate isosteres
Q Yang, EA Lachapelle, NM Kablaoui, D Webb, M Popiolek, S Grimwood, ...
ACS Medicinal Chemistry Letters 10 (6), 941-948, 2019
72019
Piperazine azaspiro derivatives
L Zhang, EA LaChapelle, CR Butler, NM Kablaoui, MA Brodney, ...
US Patent 11,524,954, 2022
12022
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