Marcia Gallacci
Marcia Gallacci
Professor de Farmacologia, UNESP
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Neutralization of snake venom phospholipase A2 toxins by aqueous extract of Casearia sylvestris (Flacourtiaceae) in mouse neuromuscular preparation
WLG Cavalcante, TO Campos, M Dal Pai-Silva, PS Pereira, CZ Oliveira, ...
Journal of Ethnopharmacology 112 (3), 490-497, 2007
Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA2 Inhibition
JI Dos Santos, FF Cardoso, AM Soares, M dal Pai Silva, M Gallacci, ...
PloS one 6 (12), e28521, 2011
Biochemical and biological evaluation of gyroxin isolated from Crotalus durissus terrificus venom
LC Barros, AM Soares, FL Costa, VM Rodrigues, AL Fuly, JR Giglio, ...
Journal of Venomous Animals and Toxins including Tropical Diseases 17, 23-33, 2011
Farmacologia integrada
R Delucia
Clube de Autores, 2012
Understanding the in vitro neuromuscular activity of snake venom Lys49 phospholipase A2 homologues
M Gallacci, WLG Cavalcante
Toxicon 55 (1), 1-11, 2010
Antagonism of myotoxic and paralyzing activities of bothropstoxin-I by suramin
M de Oliveira, WLG Cavalcante, EZ Arruda, PA Melo, MDP Silva, ...
Toxicon 42 (4), 373-379, 2003
Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids
CAH Fernandes, FF Cardoso, WGL Cavalcante, AM Soares, M Dal-Pai, ...
PLoS One 10 (7), e0133370, 2015
Biological characterization of the Amazon coral Micrurus spixii snake venom: Isolation of a new neurotoxic phospholipase A2
ALC Terra, LS Moreira-Dill, R Simoes-Silva, JRN Monteiro, ...
Toxicon 103, 1-11, 2015
Neuromuscular paralysis by the basic phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit …
WLG Cavalcante, JB Noronha-Matos, MA Timóteo, MRM Fontes, ...
Toxicology and applied pharmacology 334, 8-17, 2017
Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin
GHM Salvador, TR Dreyer, WLG Cavalcante, FF Matioli, JI Dos Santos, ...
Acta Crystallographica Section D: Biological Crystallography 71 (10), 2066-2078, 2015
Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches
GHM Salvador, FF Cardoso, AA Gomes, WLG Cavalcante, M Gallacci, ...
Scientific Reports 9 (1), 510, 2019
60Co gamma irradiation prevents Bothrops jararacussu venom neurotoxicity and myotoxicity in isolated mouse neuromuscular junction
FAD Souza, PJ Spencer, JR Rogero, N Nascimento, M Dal Pai-Silva, ...
Toxicon 40 (8), 1101-1106, 2002
Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism
GHM Salvador, TR Dreyer, AAS Gomes, WLG Cavalcante, JI Dos Santos, ...
Scientific reports 8 (1), 10317, 2018
Physicochemical parameters involved in the lethal toxicity of N, N-[(dimethylamino) ethyl]-4-substituted benzoate hydrochlorides: a QSAR study
AT Do Amaral, AC Oliveira, R Neidlein, M Gallacci, L Caprara, Y Miyazaki
European journal of medicinal chemistry 32 (5), 433-443, 1997
Neuromuscular effects of venoms and crotoxin-like proteins from Crotalus durissus ruruima and Crotalus durissus cumanensis
WLG Cavalcante, LA Ponce-Soto, S Marangoni, M Gallacci
Toxicon 96, 46-49, 2015
Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases …
GHM Salvador, WLG Cavalcante, JI Dos Santos, M Gallacci, AM Soares, ...
Toxicon 72, 52-63, 2013
Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins
FF Cardoso, RJ Borges, TR Dreyer, GHM Salvador, WLG Cavalcante, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (12), 2728-2737, 2018
Paralyzing and myotoxic effects of a recombinant bothropstoxin-I (BthTX-I) on mouse neuromuscular preparations
M Gallacci, M Oliveira, M Dal Pai-Silva, WLG Cavalcante, PJ Spencer
Experimental and Toxicologic Pathology 57 (3), 239-245, 2006
Neutralization of a bothropic PLA2-like protein by caftaric acid, a novel potent inhibitor of ophidian myotoxicity
FF Cardoso, AAS Gomes, TR Dreyer, WLG Cavalcante, M Dal Pai, ...
Biochimie 170, 163-172, 2020
Biochemical, functional, structural and phylogenetic studies on Intercro, a new isoform phospholipase A2 from Crotalus durissus terrificus snake venom
LF Vieira, AJ Magro, CAH Fernandes, BM de Souza, WLG Cavalcante, ...
Biochimie 95 (12), 2365-2375, 2013
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