| Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen LJ Sigal, S Crotty, R Andino, KL Rock Nature 402 (Suppl 6763), 25-29, 1999 | 808 | 1999 |
| Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo L Shen, LJ Sigal, M Boes, KL Rock Immunity 21 (2), 155-165, 2004 | 540 | 2004 |
| DAI senses influenza A virus genomic RNA and activates RIPK3-dependent cell death RJ Thapa, JP Ingram, KB Ragan, S Nogusa, DF Boyd, AA Benitez, ... Cell host & microbe 20 (5), 674-681, 2016 | 344 | 2016 |
| A role for NKG2D in NK cell–mediated resistance to poxvirus disease M Fang, LL Lanier, LJ Sigal PLoS pathogens 4 (2), e30, 2008 | 193 | 2008 |
| Bone marrow–derived antigen-presenting cells are required for the generation of cytotoxic T lymphocyte responses to viruses and use transporter associated with antigen … LJ Sigal, KL Rock The Journal of experimental medicine 192 (8), 1143-1150, 2000 | 176 | 2000 |
| CD94 is essential for NK cell-mediated resistance to a lethal viral disease M Fang, MT Orr, P Spee, T Egebjerg, LL Lanier, LJ Sigal Immunity 34 (4), 579-589, 2011 | 140 | 2011 |
| Antibodies and CD8+ T cells are complementary and essential for natural resistance to a highly lethal cytopathic virus M Fang, LJ Sigal The Journal of Immunology 175 (10), 6829-6836, 2005 | 139 | 2005 |
| Macrophages and dendritic cells use the cytosolic pathway to rapidly cross-present antigen from live, vaccinia-infected cells MC Ramirez, LJ Sigal The Journal of Immunology 169 (12), 6733-6742, 2002 | 137 | 2002 |
| Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking M Fang, F Roscoe, LJ Sigal Journal of Experimental Medicine 207 (11), 2369-2381, 2010 | 120 | 2010 |
| Perforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection M Fang, NA Siciliano, AR Hersperger, F Roscoe, A Hu, X Ma, ... Proceedings of the National Academy of Sciences 109 (25), 9983-9988, 2012 | 101 | 2012 |
| Poliovirus vaccine vectors elicit antigen-specific cytotoxic T cells and protect mice against lethal challenge with malignant melanoma cells expressing a model antigen S Mandl, LJ Sigal, KL Rock, R Andino Proceedings of the National Academy of Sciences 95 (14), 8216-8221, 1998 | 101 | 1998 |
| The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination RH Xu, M Cohen, Y Tang, E Lazear, JC Whitbeck, RJ Eisenberg, ... The Journal of experimental medicine 205 (4), 981-992, 2008 | 100 | 2008 |
| Targeted blockade of JAK/STAT3 signaling inhibits ovarian carcinoma growth G Gritsina, F Xiao, SW O'Brien, R Gabbasov, MA Maglaty, RH Xu, ... Molecular cancer therapeutics 14 (4), 1035-1047, 2015 | 98 | 2015 |
| The role of B7-1 and B7-2 costimulation for the generation of CTL responses in vivo LJ Sigal, H Reiser, KL Rock The Journal of Immunology 161 (6), 2740-2745, 1998 | 97 | 1998 |
| Poliovirus pathogenesis in a new poliovirus receptor transgenic mouse model: age-dependent paralysis and a mucosal route of infection S Crotty, L Hix, LJ Sigal, R Andino Journal of general virology 83 (7), 1707-1720, 2002 | 95 | 2002 |
| Replication of the human hepatitis delta virus genome is initiated in mouse hepatocytes following intravenous injection of naked DNA or RNA sequences J Chang, LJ Sigal, A Lerro, J Taylor Journal of virology 75 (7), 3469-3473, 2001 | 95 | 2001 |
| Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection D Rubio, RH Xu, S Remakus, TE Krouse, ME Truckenmiller, RJ Thapa, ... Cell host & microbe 13 (6), 701-710, 2013 | 94 | 2013 |
| Immunization with a single extracellular enveloped virus protein produced in bacteria provides partial protection from a lethal orthopoxvirus infection in a natural host M Fang, H Cheng, Z Dai, Z Bu, LJ Sigal Virology 345 (1), 231-243, 2006 | 86 | 2006 |
| Direct CD28 costimulation is required for CD8+ T cell-mediated resistance to an acute viral disease in a natural host M Fang, LJ Sigal The Journal of Immunology 177 (11), 8027-8036, 2006 | 76 | 2006 |
| Cutting edge: efficient MHC class I cross-presentation during early vaccinia infection requires the transfer of proteasomal intermediates between antigen donor and presenting cells A Serna, MC Ramirez, A Soukhanova, LJ Sigal The Journal of Immunology 171 (11), 5668-5672, 2003 | 75 | 2003 |
